Results 1 to 10 of about 26,508 (195)

Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment [PDF]

Frontiers in Immunology, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Tom Houben, Tulasi Yadati, Robbin de Kruijf, Marion J. J. Gijbels, Joost J. F. P. Luiken, Marc van Zandvoort, Marc van Zandvoort, Marc van Zandvoort, Dimitris Kapsokalyvas, Dimitris Kapsokalyvas, Dimitris Kapsokalyvas, Dieter Lütjohann, Marit Westerterp, Jogchum Plat, David Leake, Ronit Shiri-Sverdlov   +15 more
doaj   +3 more sources

Formation of inclusion complex of enrofloxacin with 2-hydroxypropyl-β-cyclodextrin [PDF]

Drug Delivery, 2020
Enrofloxacin, a third-generation fluoroquinolone, is a broad-spectrum antimicrobial drug against a lot of veterinary bacterial diseases. However, bactericidal activity of enrofloxacin is concentration-dependent and its poor aqueous solubility and bitter ...
Yili Ding, Yuchang Pang, Chamakura V. N. S. Vara Prasad, Bingyun Wang   +3 more
doaj   +3 more sources

2-Hydroxypropyl-β-cyclodextrin accesses acute and subacute infarcts in a mouse model of ischemic stroke [PDF]

Fluids and Barriers of the CNS
Ischemic stroke is a leading cause of mortality and long-term disability worldwide, with limited pharmacological interventions available. 2-hydroxypropyl-β-cyclodextrin (HPβCD), a cyclic oligosaccharide approved for use as an excipient in pharmaceutical ...
Danielle A. Becktel, Elizabeth H. Le, Jennifer B. Frye, Susan A. Whitman, Rick G. Schnellmann, Kristian P. Doyle   +5 more
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Dual 2-Hydroxypropyl-β-Cyclodextrin and 5,10,15,20-Tetrakis (4-Hydroxyphenyl) Porphyrin System as a Novel Chiral-Achiral Selector Complex for Enantioseparation of Aminoalkanol Derivatives with Anticancer Activity in Capillary Electrophoresis [PDF]

Molecules, 2021
In this study, a complex consisting of 2-hydroxypropyl-β-cyclodextrin and 5,10,15,20-tetrakis (4-hydroxyphenyl) porphyrin, (named dual chiral-achiral selector complex) was used for the determination of two novel potential anticancer agents of (I) and (II)
Błażej Grodner, Mariola Napiórkowska
doaj   +2 more sources

Inclusion complexes of 3-(3-(2-chlorophenyl)prop-2-enoyl)-4-hydroxycoumarin with 2-hydroxypropyl-(-cyclodextrin: solubility and antimicrobial activity [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
The aim of the present study is to improve the solubility and antimicrobial activity of 3-(3-(2-chlorophenyl)prop-2-enoyl)-4-hydroxycoumarin by formulating its inclusion complexes with 2-hydroxypropyl-β-cyclodextrin in solution and in solid state.
Jasmina Hadžiabdić, Selma Špirtović-Halilović, Amar Osmanović, Lejla Zahirović, Amar Elezović   +4 more
doaj   +1 more source

An Optimization Procedure for Preparing Aqueous CAR/HP-CD Aggregate Dispersions

Molecules, 2021
β-Carotene is a very important molecule for human health. It finds a large application in the food industry, especially for the development of functional foods and dietary supplements. However, β-carotene is an unstable compound and is sensitive to light,
Enrika Celitan, Ruta Gruskiene, Jolanta Sereikaite   +2 more
doaj   +1 more source

New Polymorph of β-Cyclodextrin with a Higher Bioavailability

Chemistry, 2023
A new polymorph of anhydrous β-cyclodextrin (polymorph III) was obtained and characterized for the first time using powder X-ray diffraction, infrared spectroscopy, and thermal analysis.
Askar K. Gatiatulin, Ilya S. Balakhontsev, Sofia M. Talashmanova, Marat A. Ziganshin, Valery V. Gorbatchuk   +4 more
doaj   +1 more source

Photostability of piroxicam in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]

Hemijska Industrija, 2014
The aim of this work is the protection of piroxicam from photodegradation by forming inclusion complex with 2-hydroxypropyl-β-cyclodextrin. Piroxicam:2-hydroxypropyl-β-cyclodextrin molecular inclusion complex was prepared by coprecipitation ...
Nikolić Vesna D., Ilić-Stojanović Snežana S., Nikolić Ljubiša B., Cakić Milorad D., Zdravković Aleksandar S., Kapor Agneš J., Popsavin Mirjana M.   +6 more
doaj   +1 more source

A molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin: The production and characterization thereof [PDF]

Journal of the Serbian Chemical Society, 2007
The molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin was synthesized using the coprecipitation method. The complex obtained was characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopy, as well as by DSC and X-ray diffraction ...
Nikolić Vesna, Nikolić Ljubiša, Stanković Mihajlo, Kapor Agneš, Popsavin Mirjana, Cvetković Dragan   +5 more
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Preparation and Properties of Cyclodextrin Inclusion Complexes of Hyperoside

Molecules, 2022
In order to improve the aqueous solubility and enhance the bioavailability of Hyperoside (Hyp), three inclusion complexes (ICs) of Hyp with 2-hydroxypropyl-β-cyclodextrin (2H-β-CD), β-cyclodextrin (β-CD), and methyl-β-cyclodextrin (M-β-CD) were prepared ...
Xinyu Zhang, Jianqing Su, Xiaoya Wang, Xueyan Wang, Ruixue Liu, Xiang Fu, Ying Li, Jiaojiao Xue, Xiaoli Li, Rui Zhang, Xiuling Chu   +10 more
doaj   +1 more source