Results 41 to 50 of about 26,508 (195)
Journal of Pharmacy and Bioallied Sciences, 2012 The objectives of this research were to prepare and characterize inclusion complexes of Nitrazepam with Hydroxypropyl-β-cyclodextrin (HPβCD) and Sulfobutyl ether β-cyclodextrin (SBEβCD) to study the effect of complexation on the dissolution rate of ...
J S Patel, R P Patel
doaj +1 more source
The mechanism of bensulfuron-methyl complexation with β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin and effect on soil adsorption and bio-activity. [PDF]
Sci Rep, 2019 In this work, the inclusion complexes of hydrophobic herbicide bensulfuron-methyl (BSM) with β-cyclodextrin (β-CD) and (2-hydroxypropyl)-β-CD (2-HP-β-CD) were prepared and characterized.
Geng Q +6 more
europepmc +2 more sources
Attachment of β-Cyclodextrins on Cotton and Influence of β-Cyclodextrin on Ester Formation with BTCA on Cotton [PDF]
, 2014 Cotton was treated with β-cyclodextrin (BCD) and two derivatives of β-cyclodextrin (2-hydroxypropyl-β-cyclodextrin and monochlorotriazinyl-B-cyclodextrin) to assess the optimal type for fixation with cotton. The experimental results showed that treatment
Bhaskara, Usha Rashmi +3 more
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2-Hydroxypropyl-β-cyclodextrin reduces retinal cholesterol in wild-type and Cyp27a1<sup>-/-</sup> Cyp46a1<sup>-/-</sup> mice with deficiency in the oxysterol production. [PDF]
Br J Pharmacol, 2021 2‐Hydroxypropyl‐β‐cyclodextrin (HPCD) is an FDA approved vehicle for drug delivery and an efficient cholesterol‐lowering agent. HPCD was proposed to lower tissue cholesterol via multiple mechanisms including those mediated by oxysterols.
El-Darzi N +3 more
europepmc +2 more sources
Molecules, 2023 Rutin is a natural flavonoid that carries out a variety of biological activities, but its application in medicine and food is limited by its water solubility.
Chaokang Chang +5 more
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Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles [PDF]
, 2016 Camptothecin (CPT), a molecule that shows powerful anticancer activity, is still not used in clinic due to its high hydrophobicity and poor active form's stability.
Espuelas, Socorro +5 more
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Beilstein Journal of Organic Chemistry, 2016 Since several years the inclusion of organic compounds (guests) within the hydrophobic cavity (host) of cyclodextrins (CDs) has been the subject of many investigations.
Vito Rizzi +4 more
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Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling. [PDF]
, 2016 The tumor microenvironment (TME) exerts critical pro-tumorigenic effects through cytokines and growth factors that support cancer cell proliferation, survival, motility and invasion.
Flashner-Abramson, E +6 more
core +1 more source
Results in Chemistry, 2020 This study explores the molecular association between 4-(thiophen-2-yl)-1-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)butan-1-one (RTC1), an antidiabetic compound recently reported by our research group with challenging aqueous solubility, and 2 ...
R. Devine +4 more
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Pharmaceutics, 2023 Antihistamines such as levocetirizine dihydrochloride (LC) are commercially used in oral tablets and oral drops to reduce allergic symptoms. In this study, LC was nano-spray-dried using three mucoadhesive polymers and four cyclodextrin species to form ...
Mirella Mirankó +4 more
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