2-Pyridone: monoclinic polymorph [PDF]
The asymmetric unit in the title compound, C5H5NO, comprises two independent but virtually identical molecules of 2-pyridone, and represents a monoclinic polymorph of the previously reported orthorhombic (P212121) form [Penfold (1953). Acta Cryst. 6, 591&
Edward R. T. Tiekink+2 more
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The crystal structure of the title compound, C6H7NO, is stabilized by intermolecular N—H...O hydrogen bonds, resulting in inversion dimers. The structure is further consolidated by weak C—H...O hydrogen bonds.
Shulin Mao, Luo Yanghui, Pan Meiling
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Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands [PDF]
2-Pyridone ligand-facilitated palladium-catalyzed direct C–H bond functionalization via the transient directing group strategy has become an attractive topic.
Ziting Xu+4 more
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Enzymatic synthesis of vitamin B6 precursor [PDF]
3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Prlainović Nevena Ž.+4 more
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catena-Poly[[[(2-pyridone-κO)silver(I)]-μ-2-pyridone-κ2O:O] hexafluoridophosphate] [PDF]
The asymmetric unit of the polymeric title salt, {[Ag(C5H5NO)2]PF6}n, comprises an AgI cation (located on a twofold axis), two 2-pyridone ligands (with distinct coordination modes), and half a PF6− anion (situated on a centre of inversion). The
Edward R. T. Tiekink+2 more
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New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies [PDF]
Various sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in ...
Heba M. Metwally+3 more
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A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis. [PDF]
UnlabelledIn a screen for compounds that inhibit infectivity of the obligate intracellular pathogen Chlamydia trachomatis, we identified the 2-pyridone amide KSK120.
Engström P+12 more
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Dichlorido[1-(1,10-phenanthrolin-2-yl)-2-pyridone]copper(II) [PDF]
In the title mononuclear complex, [CuCl2(C17H11N3O)], the CuII ion is in a distorted square-pyramidal coordination environment. The crystal structure is stabilized by various π–π stacking interactions in which the benzene ring, a pyridine
Jin Min Li
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Crystal structures of three hydrogen-bonded 1:2 compounds of chloranilic acid with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine [PDF]
The crystal structures of the 1:2 compounds of chloranilic acid (systematic name: 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone) with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine, namely, bis(2-pyridone) chloranilic acid, 2C5H5NO·C6H2Cl2O4, (I), bis ...
Kazuma Gotoh, Hiroyuki Ishida
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Synthesis and Evaluation of Antitumor and Anti-Angiogenesis Activity of Pyrone- or Pyridone-Embedded Analogs of Cortistatin A [PDF]
Simplified analogs of cortistatin A were synthesized and biologically evaluated to develop novel antitumor substances that target angiogenesis. To analyze the effect of substituents at positions corresponding to C-2 and/or C-4 of the A-ring, various ...
Yuri Fujimoto+4 more
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