Acta Crystallographica Section E, 2011 The crystal structure of the title compound, C6H7NO, is stabilized by intermolecular N—H...O hydrogen bonds, resulting in inversion dimers. The structure is further consolidated by weak C—H...O hydrogen bonds.
Shulin Mao, Luo Yanghui, Pan Meiling
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Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds [PDF]
Hemijska Industrija, 2014 2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications.
Mijin Dušan Ž. +3 more
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2-Pyridone: monoclinic polymorph [PDF]
Acta Crystallographica Section E, 2009 The asymmetric unit in the title compound, C5H5NO, comprises two independent but virtually identical molecules of 2-pyridone, and represents a monoclinic polymorph of the previously reported orthorhombic (P212121) form [Penfold (1953). Acta Cryst. 6, 591&
Edward R. T. Tiekink +2 more
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Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands [PDF]
Molecules2-Pyridone ligand-facilitated palladium-catalyzed direct C–H bond functionalization via the transient directing group strategy has become an attractive topic.
Ziting Xu +4 more
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Diversity-oriented functionalization of 2-pyridones and uracils [PDF]
Nature Communications, 2021 Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of ...
Yong Shang +8 more
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New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies [PDF]
BMC ChemistryVarious sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in ...
Heba M. Metwally +3 more
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Dichlorido[1-(1,10-phenanthrolin-2-yl)-2-pyridone]copper(II) [PDF]
Acta Crystallographica Section E, 2008 In the title mononuclear complex, [CuCl2(C17H11N3O)], the CuII ion is in a distorted square-pyramidal coordination environment. The crystal structure is stabilized by various π–π stacking interactions in which the benzene ring, a pyridine
Jin Min Li
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Crystal structures of three hydrogen-bonded 1:2 compounds of chloranilic acid with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2017 The crystal structures of the 1:2 compounds of chloranilic acid (systematic name: 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone) with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine, namely, bis(2-pyridone) chloranilic acid, 2C5H5NO·C6H2Cl2O4, (I), bis ...
Kazuma Gotoh, Hiroyuki Ishida
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Synthesis and Evaluation of Antitumor and Anti-Angiogenesis Activity of Pyrone- or Pyridone-Embedded Analogs of Cortistatin A [PDF]
Marine DrugsSimplified analogs of cortistatin A were synthesized and biologically evaluated to develop novel antitumor substances that target angiogenesis. To analyze the effect of substituents at positions corresponding to C-2 and/or C-4 of the A-ring, various ...
Yuri Fujimoto +4 more
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2-Bromopyridines as Versatile Synthons for Heteroarylated 2-Pyridones via Ru(II)-Mediated Domino C–O/C–N/C–C Bond Formation Reactions [PDF]
MoleculesA novel methodology for the synthesis of 2-pyridones bearing a 2-pyridyl group on nitrogen and carbon atoms, starting from 2-bromopyridines, was developed employing a simple Ru(II)–KOPiv–Na2CO3 catalytic system.
Miha Drev +6 more
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