Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands [PDF]
Molecules2-Pyridone ligand-facilitated palladium-catalyzed direct C–H bond functionalization via the transient directing group strategy has become an attractive topic.
Ziting Xu +4 more
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A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes [PDF]
mBio, 2023 Listeria monocytogenes is a facultative Gram-positive bacterium that causes listeriosis, a severe foodborne disease. We previously discovered that ring-fused 2-pyridone compounds can decrease virulence factor expression in Listeria by binding and ...
Hasan Tükenmez +10 more
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New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies [PDF]
BMC ChemistryVarious sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in ...
Heba M. Metwally +3 more
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Dichlorido[1-(1,10-phenanthrolin-2-yl)-2-pyridone]copper(II) [PDF]
Acta Crystallographica Section E, 2008 In the title mononuclear complex, [CuCl2(C17H11N3O)], the CuII ion is in a distorted square-pyramidal coordination environment. The crystal structure is stabilized by various π–π stacking interactions in which the benzene ring, a pyridine
Jin Min Li
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Crystal structures of three hydrogen-bonded 1:2 compounds of chloranilic acid with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2017 The crystal structures of the 1:2 compounds of chloranilic acid (systematic name: 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone) with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine, namely, bis(2-pyridone) chloranilic acid, 2C5H5NO·C6H2Cl2O4, (I), bis ...
Kazuma Gotoh, Hiroyuki Ishida
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2-Bromopyridines as Versatile Synthons for Heteroarylated 2-Pyridones via Ru(II)-Mediated Domino C–O/C–N/C–C Bond Formation Reactions [PDF]
MoleculesA novel methodology for the synthesis of 2-pyridones bearing a 2-pyridyl group on nitrogen and carbon atoms, starting from 2-bromopyridines, was developed employing a simple Ru(II)–KOPiv–Na2CO3 catalytic system.
Miha Drev +6 more
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Arabian Journal of Chemistry, 2015 A series of eleven new 5-arylazo-6-hydroxy-4-(4-methoxyphenyl)-3-cyano-2-pyridone dyes was synthesized and their absorption spectra were recorded in twenty solvents in the range 300–600 nm.
Adel Alimmari +5 more
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Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones [PDF]
Molecules, 2012 Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao +9 more
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Synthesis and characterization of Cu and Fe (1:2) metal complexes based on their substituted pyridones acid dyes and their application on wool fabrics [PDF]
Journal of Chemistry Letters, 2022 In this study, the investigation deals with synthesis of acid dyes from 4-amino-1-(4-sulfophenyl)- 3-methyl-5-pyrazolone and their pyridone derivatives and their metal complexes (Cu (II)and Fe (II)).
Olamide Ajani +2 more
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Solid-Phase Synthesis of Diverse Macrocycles by Regiospecific 2‑Pyridone Formation: Scope and Applications [PDF]
JACS AuSkander A. Abboud, Thomas Kodadek
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