Results 41 to 50 of about 6,997 (207)

Synthesis of Some New Enaminoketones, Analogous of Milrinone, 4,Pyrones and Related 4-Pyridones [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1996
Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.
Aziz Shahrisa, Salar Hemmati
doaj  

Self‐Assembly of a Customizable Library of Nickel Trifluoromethylation Catalysts via Selective C‒F and C‒O Bond Cleavage

Angewandte Chemie International Edition, Accepted Article.
Using a combination of metal‐promoted reactivity, in‐situ covalent bond modification, and hydrogen bonding‐promoted fluorine labilization, a unified approach was developed to self‐assemble a library of customizable ligand architectures directly at the nickel center via selective cleavage of C‒F or C‒O bonds and the formation of C‒C or C‒N bonds.
Aleksandr Sorvanov, Shubham Deolka, Eugene Khaskin, Robert R. Fayzullin, Serhii Vasylevskyi, Julia Khusnutdinova   +5 more
wiley   +1 more source

Electronic Conductive Metal–Organic Frameworks for Aqueous Rechargeable Zinc‐Ion Battery Cathodes: Design, Progress, and Prospects

Carbon Energy, EarlyView.
Schematic of the working principle of aqueous ZIBs and the benefits of electronic conductive metal–organic frameworks (EC‐MOFs) as cathode materials. ABSTRACT Zinc‐ion batteries (ZIBs) have significant potential for advancements in energy storage systems owing to their high level of safety and theoretical capacity. However, ZIBs face several challenges,
Chuntao Yang, Youlin Xiang, Yingjian Yu
wiley   +1 more source

6-Methyl-2-pyridone pentahydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2004
Crystals of the title compound, C6H7NO·5H2O, were grown over a period of several weeks from an aqueous solution of the commercial compound. The mol­ecule crystallizes in space group P\overline 1 and there are two independent 6-methyl-2-pyridone (Hmhp) mol­ecules in the asymmetric unit, together with ten mol­ecules of water.
Clegg W, Nichol GS
openaire   +2 more sources

Crystal structure of N-[6-amino-5-(benzo[d]thiazol-2-yl)-3-cyano-4-methylsulfanyl-2-oxo-1,2-dihydropyridin-1-yl]-4-methylbenzenesulfonamide dimethylformamide monosolvate

Acta Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, C21H17N5O3S3·C3H7NO, the toluenesulfonamide ring and the combined ring system involving the pyridone and benzothiazole rings subtend an interplanar angle of 39.86 (4)°.
Rasha A. Azzam, Galal H. Elgemeie, Rasha E. Elsayed, Peter G. Jones   +3 more
doaj   +1 more source

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

ChemMedChem, EarlyView.
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet, Laurent Maveyraud, David Rengel, Valérie Guillet, Gabriel Publicola, Frédéric Rodriguez, Christian Lherbet, Lionel Mourey   +7 more
wiley   +1 more source

Synthesis of Functionalized Bicyclic Pyridones Containing the Dithiocarbamate Group Using Thioazlactones, Diamines, and Nitroketene Dithioacetal

SynOpen, 2021
An efficient method for the synthesis of highly substituted bicyclic pyridone derivatives containing the dithiocarbamate group is reported via a one-pot three-component reaction of 2-(alkylthio)thio­azlactones, diamines, and nitroketene dithioacetal in ...
Marziyeh Saeedi, Maryam Khoshdoun, Salman Taheri, Azim Ziyaei Halimehjani, Aliasghar Mohammadi, Mohammad Reza Halvagar, Vahid Amani   +6 more
doaj   +1 more source

Deferasirox Derivatives as Inhibitors of Kallikrein‐Related Peptidases Associated to Neurodegenerative Diseases

ChemMedChem, EarlyView.
Dysregulated proteolysis mediated by kallikrein‐related peptidases (KLKs) and iron overload are involved in the progression of neurodegenerative diseases. Deferasirox, an clinically‐approved iron chelator, and its newly synthesized derivatives have been identified as inhibitors of major central nervous system KLKs with low cytotoxicity and effective ...
Rilès Boumali, Elodie David, Nancy Chaaya, Morane Lucas, Sabrina Aït Amiri, Valérie Lefort, Anthony Nina‐Diogo, Michèle Salmain, Isabelle Petropoulos, Vincent Corcé, Chahrazade El Amri, Candice Botuha   +11 more
wiley   +1 more source

Indirect Anti‐Markovnikov Hydrofunctionalization of Terminal Alkenes via an Alkenyl Thianthrenium Intermediate

Angewandte Chemie, Volume 137, Issue 21, May 19, 2025.
A two‐stage dication pool strategy using alkenyl thianthrenium intermediates has been developed for anti‐Markovnikov hydrofunctionalization. This method differs from previous approaches in its reaction mechanism and addresses their most significant limitation, namely, the restricted generality of the nucleophile. The approach has been extended to other
Bence Sóvári, Péter Angyal, István J. Babcsányi, András M. Kotschy, Ádám Dudás, Gábor Turczel, Szilárd Varga, Tibor Soós   +7 more
wiley   +2 more sources

catena-Poly[[(nitrato-κ2O,O′)silver(I)]-μ3-4-pyridone-κ3O:O:O]

Acta Crystallographica Section E, 2009
In the title complex, [Ag(NO3)(C5H5NO)]n, the AgI atom is coordinated by two O atoms from two different 4-pyridone ligands and two O atoms from one nitrate anion, displaying a nearly planar coordination geometry.
Xian-Ge Wu, Jun-Xia Xiao, Liang Qin
doaj   +1 more source