Acceleration of hemiacetal cleavage through hydrogen bonding : a new synthetic catalyst with balanced conformational flexibility and preorganization [PDF]
, 1991 Hemiacetal cleavage catalyst 1 was designed, synthesized, and shown to be effective in promoting glycolaldehyde dimer dissociation and tetramethylglucose ...
Bartoletti M. +4 more
core +1 more source
Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands
Crystals, 2018 Substitution of methanol in [Zn(quin)2(CH3OH)2] (quin− denotes an anionic form of quinoline-2-carboxylic acid, also known as quinaldinic acid) with pyridine (Py) or its substituted derivatives, 3,5-lutidine (3,5-Lut), nicotinamide (Nia), 3 ...
Barbara Modec
doaj +1 more source
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. [PDF]
, 2017 Pericyclic reactions-which proceed in a concerted fashion through a cyclic transition state-are among the most powerful synthetic transformations used to make multiple regioselective and stereoselective carbon-carbon bonds.
Chen, Mengbin +9 more
core +1 more source
Synthesis, structure and solvatochromic properties of 3-cyano-4,6-diphenyl-5-(3- and 4-substituted phenylazo)-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2010 A series of some new pyridone arylazo dyes was synthesized from the corresponding diazonium salts and 3-cyano-4,6-diphenyl-2-pyridone using the classical reaction for the synthesis of the azo compounds.
NINA TODOROVIĆ +5 more
doaj
rac-2-Methyl-3,4,5,6-tetrahydro-2H-2,6-methano-1,3-benzoxazocin-4-one
Acta Crystallographica Section E, 2010 The title compound, C12H13NO2, represents a conformationally restricted 2-pyridone analogue of 1,4-dihydropyridine-type calcium antagonists and was selected for a crystal structure determination in order to explore some aspects of drug-receptor ...
Viktor Kettmann +2 more
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Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. [PDF]
, 2014 Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA receptor responses but the mode of block has not been characterized.
Chen, Chao-Yin +3 more
core +3 more sources
Gas-phase Lifetimes of Nucleobase Analogues by Picosecond Pumpionization and Streak Techniques
CHIMIA, 2014 The picosecond (ps) timescale is relevant for the investigation of many molecular dynamical processes such as fluorescence, nonradiative relaxation, intramolecular vibrational relaxation, molecular rotation and intermolecular energy transfer, to
Susan Blaser +3 more
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Rapid changes in Atlantic grey seal milk from birth to weaning – immune factors and indicators of metabolic strain [PDF]
, 2017 True seals have the shortest lactation periods of any group of placental mammal. Most are capital breeders that undergo short, intense lactations, during which they fast while transferring substantial proportions of their body reserves to their pups ...
Bawazeer, Sami +6 more
core +3 more sources
Metabolomics application in maternal-fetal medicine [PDF]
, 2013 Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L +4 more
core +4 more sources
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, EarlyView.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source