Results 31 to 40 of about 1,287 (164)
Treatment of 5-arylidene-2-thiohydantoin (1a-d) with alkyl bromoacetate and chloroacetic acid gave the esters 2a-f and the acids 2g-j, respectively. 2a was refluxed with concentrated hydrochloric acid to give 5-benzylidene hydantoin. 2 was cyclized with acetic anhydride to give the bicyclic product 3. 5-Arylidene-2-thiohydantoin derivatives (1a, b) and
A. F. A. Shalaby +2 more
openaire +1 more source
Different types of 3-substituted 4H-4-oxobenzopyrans were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the aldol condensation of 3-formylchromones with 2-imino-1-methylimidazolidine-
Nada Pronayova +4 more
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A New Polymorph of 2-Thiohydantoin
A new polymorphic crystal of the title compound, C3H4N2OS, belongs to space group P1 with cell dimensions of a = 4.0520(9)A, b = 6.550(1)A, c = 9.170(2)A, α = 100.148(4)°, β = 100.814(4)°, γ = 96.831(4)°, R1 = 0.069. Neighboring molecules are connected to form cyclic dimers via two types of hydrogen bonds, one between the thioamide groups and the other
Toshiakzu OGAWA +7 more
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Synthese von 6-Thioxo-1,2,5-oxadiazinan-3-onen und Umwandlung in 3-Amino-2-thiohydantoine und 3-Hydroxy-2-thiohydantoine / Synthesis of 6-Thioxo-1,2,5-oxadiazinan-3-ones and Transformation into 3-Amino-2-thiohydantoins and 3-Hydroxy-2-thiohydantoins [PDF]
6-Thioxo-1,2,5-oxadiazinan-3-ones 5, easily available by cyclic thiocarbonylation of Nα ,Ndisubstituted α-aminocarbohydroxamic acids 4 with 1,1′-thiocarbonyldiimidazole, are transformed by hydrazine or hydroxylamine into 3-amino-2-thiohydantoins 6 and 3-hydroxy-2-thiohydantoins 7.
Detlef Geffken, Alf Ploetz
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Potensi Senyawa Hidrazon berbasis Turunan 2-Tiohidantoin dan Hidrazida sebagai Inhibitor Protein E6 pada Kanker Serviks secara In Silico [PDF]
Setiap tahun, prevalensi penyakit kanker leher rahim di dunia semakin meningkat. Kanker serviks dapat terjadi akibat infeksi Human Papillomavirus (HPV).
Abidiy, Syafri Izzat +5 more
core +2 more sources
A highly divergent synthesis of regioisomeric thiohydantoins and pseudothiohydantoins spiro-fused to a pharmacologically valuable pyrrole-2-one fragment involving the reaction of [e]-fused 1H-pyrrole-2,3-diones with thioureas was developed.
Aleksandr I. Kobelev +5 more
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A novel series of substituted 2-thiohydantoin incorporated with benzoimidazole, pyrazole, triazole and/or benzoxazole moieties has been synthesized using (E)-3-[1-(4-bromophenyl)ethylideneamino]-2-thioxoimidazolidin-4-one 1 as the key starting material ...
Heba A. Elhady +2 more
doaj +1 more source
In situ acetonitrile/water mixed solvents: An ecofriendly synthesis and structure Explanations of Cu(II), Co(II), and Ni(II) complexes of thioxoimidazolidine [PDF]
. The bidentate oxoacetate derivative of 4-oxo-2-thiazolidine 4ligand (L1) synthesized by the reaction of 1-(1-(Pyridin-3-yl)ethylideneamino)-2-thioxoimidazolidin-4-one 3 with diethyl oxalate with both traditional and microwave irradiation methods.
A. Saad, H. +3 more
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1,3-Dipolar cycloaddition reactions of nitrile imines are a powerful tool for the construction of spirocyclic frameworks, yet controlling chemoselectivity remains challenging when dipolarophiles contain multiple reactive sites.
Maria E. Filkina +4 more
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Advances in Chemistry of Isothiocyanate-derived Colourants
This study is focused on the reactions of isothiocyanates (ITCs) in the presence of amino compounds leading to coloured structures via substituted 2-thiohydantoins.
K. Cejpek, J. Velíšek
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