Results 141 to 150 of about 12,744 (156)

25-hydroxycholesterol triggers antioxidant signaling in mouse atria

Prostaglandins & Other Lipid Mediators
Oxysterol, 25-hydroxycholesterol (25HC), is a potent regulator of immune reactions, its synthesis greatly increases by macrophages during inflammation. We hypothesize that 25HC can have cardioprotective effects by limiting consequences of excessive β-adrenoceptor (βAR) stimulation, particularly reactive oxygen species (ROS) production, in mouse atria ...
Julia G, Odnoshivkina, Alexey M, Petrov
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Esterification of cholesterol and 25-hydroxycholesterol by rat liver microsomes

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1983
The properties of an enzyme in rat liver microsomes was described that catalyzed the formation of 25-hydroxycholesteryl ester in the presence of labeled sterol and oleoyl-CoA. The reaction was similar in several respects to that of cholesteryl ester formation by acyl-CoA: cholesterol acyltransferase.
A H, Lichtenstein, P, Brecher
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Diminution of L cell microvilli following exposure to 25-hydroxycholesterol

Cell Biology International Reports, 1979
The effect of sterol depletion on the topology of mouse L cells was studied by scanning electron microscopy. Treatment of cells with 25-hydroxycholesterol inhibited the synthesis of cellular sterol and diminished the number of microvilli on the cell surface.
P S, Lin, H W, Chen
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The effect of 25-hydroxycholesterol on accumulation of intracellular calcium

Cell Calcium, 1991
Liposomes prepared with 25-hydroxycholesterol and egg phosphatidylcholine (PC) were incubated with bovine arterial smooth muscle cells for 8 h at 37 degrees C. Cells incubated in the absence of liposomes or with liposomes containing cholesterol and PC were used as controls.
Q, Zhou, S, Jimi, T L, Smith, F A, Kummerow   +3 more
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25-Hydroxycholesterol Activates a Cytochrome c Release-Mediated Caspase Cascade

Biochemical and Biophysical Research Communications, 2000
We have previously shown that 25-hydroxycholesterol (25-OHC) treated CHO-K1 cells could be used as a model to investigate the signaling pathway of apoptosis induced by oxidized LDL in vascular cells. In the present study, we examine the execution phase of the apoptotic pathway in CHO-K1 cell death induced by 25-OHC.
Yang, Lin, Sinensky, Michael S.
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25-Hydroxycholesterol inhibits Hantavirus infection by reprogramming cholesterol metabolism

Free Radical Biology and Medicine
Hantavirus causes two types of acute diseases: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. It is a major health concern due to its high mortality and lack of effective treatment. Type I interferon treatment has been suggested to be effective against hantavirus when treated in advance.
Yamei Dang, Yuan Wang, Jing Wei, Hui Zhang, Qiqi Yang, Bin Wang, Jia Li, Chuantao Ye, Yang Chen, Peijun Han, Xiaolei Jin, Jia Wang, Xiaohui Bao, He Liu, Hongwei Ma, Liang Zhang, Linfeng Cheng, Yangchao Dong, Yinlan Bai, Yinghui Li, Yingfeng Lei, Zhikai Xu, Fanglin Zhang, Wei Ye   +23 more
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25-Hydroxycholesterol promotes migration and invasion of lung adenocarcinoma cells

Biochemical and Biophysical Research Communications, 2017
25-hydroxycholesterol (25-HC) is enzymatically produced by cholesterol 25-hydorxylase in various organs and is involved in many processes, including lipid metabolism, inflammation and the immune response. However, the role of 25-HC in the migration and invasion of lung adenocarcinoma (ADC) cells remains largely unknown.
Li, Chen, Lishan, Zhang, Guozhe, Xian, Yinping, Lv, Yanliang, Lin, Yibing, Wang   +5 more
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Cytosolic 25-hydroxycholesterol binding activity of Chinese hamster ovary cells

Archives of Biochemistry and Biophysics, 1981
Abstract DEAE-Sephadex chromatography of cytosols of Chinese hamster ovary cells incubated with tritium-labeled 25-hydroxycholesterol shows a peak of specific binding activity. This binding activity can be assayed by determining the amount of labeled 25-hydroxycholesterol in cytosol which is refractory to adsorption to activated charcoal at high ...
M, Sinensky, G, Mueller
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A comparison of solution properties of cholesterol and 25-hydroxycholesterol

Archives of Biochemistry and Biophysics, 1981
Abstract Although 25-hydroxycholesterol is a potent effector of mammalian cellular cholesterol biosynthesis, cholesterol itself is not. In an effort to explain this difference, the critical micellar concentration, liposome-water partition coefficient, and capacity for acyl chain ordering of 25-hydroxycholesterol are measured and compared to those of ...
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A synthesis of 25-hydroxycholesterol

Tetrahedron Letters, 1977
William G. Salmond, Marie C. Sobala, Keith D. Maisto   +2 more
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