Results 141 to 150 of about 1,842,116 (207)

Proteomic analysis reveals inhibition of mevalonate and glycolysis pathways in hepatocytes by 27-hydroxycholesterol. [PDF]

Biochem J
Shim WS, Lee S, Azamov B, Lee C, Kang Y, Lee KM, Hong C, Kwon SM, Kim K, Lee D, Yoon JH, Song P.   +11 more
europepmc   +1 more source

24-Hydroxycholesterol is a substrate for hepatic cholesterol 7 alpha-hydroxylase (CYP7A)

, 2000
(24S)-Hydroxycholesterol is formed from cholesterol in the brain and is important for cholesterol homeostasis in this organ. Elimination of (24S)-hydroxycholesterol has been suggested to occur in the liver but little is known about the metabolism of this
Toll, Anders,, Bjorkhem, Ingemar, Wikvall, Kjell,, Norlin, Maria,   +3 more
core  

ZMYND8 is a master regulator of 27-hydroxycholesterol that promotes tumorigenicity of breast cancer stem cells. [PDF]

Sci Adv, 2022
Luo M, Bao L, Chen Y, Xue Y, Wang Y, Zhang B, Wang C, Corley CD, McDonald JG, Kumar A, Xing C, Fang Y, Nelson ER, Wang JE, Wang Y, Luo W.   +15 more
europepmc   +1 more source

27-Hydroxycholesterol triggers microglial senescence subsequent to iron over-loading contributes to brain aging, suppressed by Deferoxamine. [PDF]

NPJ Aging
Yu C, Wang W, Shi L, Ma R, Zhang Y, Zhang C, Wang X, Wang T, Zheng Y, Tian J.   +9 more
europepmc   +1 more source

27-Hydroxycholesterol-Induced Dysregulation of Cholesterol Metabolism Impairs Learning and Memory Ability in ApoE ε4 Transgenic Mice. [PDF]

Int J Mol Sci, 2022
Wang Y, Hao L, Wang T, Liu W, Wang L, Ju M, Feng W, Xiao R.   +7 more
europepmc   +1 more source

Association Between Rest-Activity Rhythm and 27-Hydroxycholesterol (27-OH) in Patients with Amnestic Mild Cognitive Impairment (aMCI). [PDF]

J Clin Med
Kim SJ, Lee JH, Jang JW, Choi M, Suh IB.
europepmc   +1 more source

Role of reactive oxygen species in regulating 27-hydroxycholesterol-induced apoptosis of hematopoietic progenitor cells and myeloid cell lines. [PDF]

Cell Death Dis, 2022
Woo SY, Lee H, Park SM, Choi HS, Kim J, Kwon M, Sohn J, Nam JH, Kim HS, Song P, Baryawno N, Kim YH, Kim K, Lee D.   +13 more
europepmc   +1 more source

27-Hydroxycholesterol Binds GPER and Induces Progression of Estrogen Receptor-Negative Breast Cancer. [PDF]

Cancers (Basel), 2022
Avena P, Casaburi I, Zavaglia L, Nocito MC, La Padula D, Rago V, Dong J, Thomas P, Mineo C, Sirianni R, Shaul PW.   +10 more
europepmc   +1 more source

NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss. [PDF]

FASEB Bioadv
Li B, Zhou W, Yu Y, Chen B, Lv Z, Zhang J, Zhang T, Sun S, Zhou L, Wang M.   +9 more
europepmc   +1 more source

27-Hydroxycholesterol induces expression of zonula occludens-1 in monocytic cells via multiple kinases pathways. [PDF]

Sci Rep, 2022
Cho HR, Kim BY, Kim K, Lee D, Eo SK, Son Y.   +5 more
europepmc   +1 more source