Recovery and Visualization of 3D Structure of Chromosomes from Tomographic Reconstruction Images [PDF]
EURASIP Journal on Advances in Signal Processing, 2006 The objectives of this work include automatic recovery and visualization of a 3D chromosome structure from a sequence of 2D tomographic reconstruction images taken through the nucleus of a cell.
Tsap Leonid V +3 more
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The “lnc” between 3D chromatin structure and X chromosome inactivation [PDF]
Seminars in Cell & Developmental Biology, 2016 The long non-coding RNA Xist directs a remarkable instance of developmentally regulated, epigenetic change known as X Chromosome Inactivation (XCI). By spreading in cis across the X chromosome from which it is expressed, Xist RNA facilitates the creation
Plath, Kathrin +3 more
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Neocentromeres Provide Chromosome Segregation Accuracy and Centromere Clustering to Multiple Loci along a Candida albicans Chromosome. [PDF]
PLoS Genetics, 2016 Assembly of kinetochore complexes, involving greater than one hundred proteins, is essential for chromosome segregation and genome stability. Neocentromeres, or new centromeres, occur when kinetochores assemble de novo, at DNA loci not previously ...
Laura S Burrack +12 more
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A maximum likelihood algorithm for reconstructing 3D structures of human chromosomes from chromosomal contact data [PDF]
BMC Genomics, 2018 Background The development of chromosomal conformation capture techniques, particularly, the Hi-C technique, has made the analysis and study of the spatial conformation of a genome an important topic in bioinformatics and computational biology.
Oluwatosin Oluwadare +2 more
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GSDB: a database of 3D chromosome and genome structures reconstructed from Hi-C data [PDF]
BMC Molecular and Cell Biology, 2020 Advances in the study of chromosome conformation capture technologies, such as Hi-C technique - capable of capturing chromosomal interactions in a genome-wide scale - have led to the development of three-dimensional chromosome and genome structure ...
Oluwatosin Oluwadare +4 more
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EVR: reconstruction of bacterial chromosome 3D structure models using error-vector resultant algorithm [PDF]
BMC Genomics, 2019 Background More and more 3C/Hi-C experiments on prokaryotes have been published. However, most of the published modeling tools for chromosome 3D structures are targeting at eukaryotes. How to transform prokaryotic experimental chromosome interaction data
Kang-Jian Hua, Bin-Guang Ma
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Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. [PDF]
PLoS Biology, 2005 Studies of higher-order chromatin arrangements are an essential part of ongoing attempts to explore changes in epigenome structure and their functional implications during development and cell differentiation.
Andreas Bolzer +10 more
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Development of Deletion Lines for Chromosome 3D of Bread Wheat
Frontiers in Plant Science, 2020 The identification of genes of agronomic interest in bread wheat (Triticum aestivum L.) is hampered by its allopolyploid nature (2n = 6x = 42; AABBDD) and its very large genome, which is largely covered by transposable elements.
Radim Svačina +7 more
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Orientation-dependent Dxz4 contacts shape the 3D structure of the inactive X chromosome [PDF]
Nature Communications, 2018 The inactive X chromosome condenses into a bipartite structure. Here the authors use cells with allelic deletions or inversions to show that the Dxz4 locus is necessary to maintain the bipartite structure and that Dxz4 orientation controls the ...
G. Bonora +10 more
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3D chromosome structure and chromatin proteomics
, 2016 Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.Cataloged from PDF version of thesis. "May 2016."Includes bibliographical references.The selective interpretation of the genome through transcription enables the ...
Dadon, Daniel Benjamin
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