Cytomolecular identification of individual wheat-wheat chromosome arm associations in wheat-rye hybrids [PDF]
Chromosome pairing in the meiotic metaphase I of wheatrye hybrids has been characterized by sequential genomic and fluorescent in situ hybridization allowing not only the discrimination of wheat and rye chromosomes, but also the identification of the
Badaeva ED +56 more
core +1 more source
Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data
Abstract Chromosomes are not positioned randomly within a nucleus, but instead, they adopt preferred spatial conformations to facilitate necessary long-range gene–gene interactions and regulations. Thus, obtaining the 3D shape of chromosomes of a genome is critical for understanding how the genome folds, functions and how its genes ...
Trieu, Tuan, Cheng, Jianlin
openaire +2 more sources
Inferring chromosome radial organization from Hi-C data
Background The nonrandom radial organization of eukaryotic chromosome territories (CTs) inside the nucleus plays an important role in nuclear functional compartmentalization. Increasingly, chromosome conformation capture (Hi-C) based approaches are being
Priyojit Das +2 more
doaj +1 more source
Contrasting roles of condensin I and condensin II in mitotic chromosome formation [PDF]
© 2012. Published by The Company of Biologists LtdIn vertebrates, two condensin complexes exist, condensin I and condensin II, which have differing but unresolved roles in organizing mitotic chromosomes.
Abe +69 more
core +2 more sources
Calculation of 3D genome structures for comparison of chromosome conformation capture experiments with microscopy: An evaluation of single-cell Hi-C protocols. [PDF]
Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell variability in the organization and packaging of genomes.
Basu, Srinjan +3 more
core +2 more sources
Manifold Based Optimization for Single-Cell 3D Genome Reconstruction. [PDF]
The three-dimensional (3D) structure of the genome is important for orchestration of gene expression and cell differentiation. While mapping genomes in 3D has for a long time been elusive, recent adaptations of high-throughput sequencing to chromosome ...
Jonas Paulsen +2 more
doaj +1 more source
Motion and disparity estimation with self adapted evolutionary strategy in 3D video coding [PDF]
Real world information, obtained by humans is three dimensional (3-D). In experimental user-trials, subjective assessments have clearly demonstrated the increased impact of 3-D pictures compared to conventional flat-picture techniques. It is reasonable,
Adedoyin, S +3 more
core +1 more source
Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework [PDF]
Abstract Any conformational ensemble of biopolymers, whether they are proteins or chromosomes, can be described using contact matrices derived from experimental or computational studies. One powerful approach to extract meaningful information from these contact matrices is to perform principal component analysis (PCA) on the covariance ...
Lindsay, Richard J. +3 more
openaire +2 more sources
Inter- and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys [PDF]
Recently it has been shown that the gene-density correlated radial distribution of human 18 and 19 homologous chromosome territories (CTs) is conserved in higher primates in spite of chromosomal rearrangements that occurred during evolution.
ISHIDA Takafumi +5 more
core +1 more source
The 3D Genome Browser: A web-based browser for visualizing 3D genome organization and long-range chromatin interactions [PDF]
Here, we introduce the 3D Genome Browser, http://3dgenome.org, which allows users to conveniently explore both their own and over 300 publicly available chromatin interaction data of different types.
Choudhary, Mayank N.K. +12 more
core +2 more sources

