Results 41 to 50 of about 186,280 (286)

Physical mapping integrated with syntenic analysis to characterize the gene space of the long arm of wheat chromosome 1A [PDF]

, 2013
Background: Bread wheat (Triticum aestivum L.) is one of the most important crops worldwide and its production faces pressing challenges, the solution of which demands genome information. However, the large, highly repetitive hexaploid wheat genome has
Akpınar, Bala Anı, Aydınoğlu, Fatma, Bellec, Arnaud, Berges, Helene, Budak, Hikmet, Cattonaro, Federica, Dolezel, Jaroslav, Frenkel, Zeev, Kantar, Melda, Korol, Abraham, Lucas, Stuart J., Magni, Federica, Safar, Jan, Simkova, Hana, Vautrin, Sonia, Weinstein, Zohar Bat-El   +15 more
core   +10 more sources

Inference of chromosome 3D structures from GAM data by a physics computational approach

Methods, 2020
The combination of modelling and experimental advances can provide deep insights for understanding chromatin 3D organization and ultimately its underlying mechanisms. In particular, models of polymer physics can help comprehend the complexity of genomic contact maps, as those emerging from technologies such as Hi-C, GAM or SPRITE.
Fiorillo L., Bianco S., Chiariello A. M., Barbieri M., Esposito A., Annunziatella C., Conte M., Corrado A., Prisco A., Pombo A., Nicodemi M.   +10 more
openaire   +5 more sources

Applications of image analysis in plant chromosome and chromatin structure study

Quantitative Biology, 2022
Background The use of image analysis to understand the structure of chromosome and chromatin is critical to the study of genetic evolution and diversification.
Nobuko Ohmido, Astari Dwiranti, Seiji Kato, Kiichi Fukui   +3 more
doaj   +1 more source

Towards many colors in FISH on 3D-preserved interphase nuclei [PDF]

, 2006
The article reviews the existing methods of multicolor FISH on nuclear targets, first of all, interphase chromosomes. FISH proper and image acquisition are considered as two related components of a single process.
Albiez, H., Benecletti, P. A., Bolzer, A., Cremer, M., Cremer, T., Joffe, B., Müller, Stefan, Solovei, Irina, Speicher, Michael R., Walter, J.   +9 more
core   +1 more source

Large-scale 3D chromatin reconstruction from chromosomal contacts

BMC Genomics, 2019
Background Recent advances in genome analysis have established that chromatin has preferred 3D conformations, which bring distant loci into contact. Identifying these contacts is important for us to understand possible interactions between these loci ...
Yanlin Zhang, Weiwei Liu, Yu Lin, Yen Kaow Ng, Shuaicheng Li   +4 more
doaj   +1 more source

Dynamic interplay between structural variations and 3D chromosome organization in pancreatic cancer [PDF]

, 2021
Summary Structural variations (SVs) are the greatest source of variation in the genome and can lead to oncogenesis. However, the identification and interpretation of SVs in human pancreatic cancer remain largely undefined due to technological limitations.
Yongxing Du, Zongting Gu, Zongze Li, Zan Yuan, Yue Zhao, Xiaohao Zheng, Xiaochen Bo, Hebing Chen, Chengfeng Wang   +8 more
openaire   +1 more source

Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]

, 2019
Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate ...
Bai, Fan, Chen, Hengyu, Li, Ruoyan, Taft, David A., Xing, Jianhua, Yao, Guang, Zhang, Jingyu   +6 more
core   +3 more sources

Correction to: GSDB: a database of 3D chromosome and genome structures reconstructed from Hi-C data [PDF]

BMC Molecular and Cell Biology, 2020
An amendment to this paper has been published and can be accessed via the original article.
Oluwatosin Oluwadare, Max Highsmith, Douglass Turner, Erez Lieberman Aiden, Jianlin Cheng   +4 more
openaire   +3 more sources

The radial arrangement of the human chromosome 7 in the lymphocyte cell nucleus is associated with chromosomal band gene density [PDF]

, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ Springer-Verlag 2008.In the nuclei of human lymphocytes, chromosome territories are distributed according to the average gene density of ...
A Bolzer, A Ono, AM Boutanaev, B Dutrillaux, BA Boggs, C Federico, C Federico, C Federico, C Federico, C Federico, Catia Daniela Cantarella, CM Clemson, Concetta Federico, D Zink, E Lukasova, ED Andrulis, EV Volpi, G Bernardi, G D’Onofrio, H Tanabe, H Tanabe, HA Foster, I Solovei, IHGSC (International Human Genome Sequencing Consortium), J Ferreira, J Strouboulis, J Zhou, JA Croft, JJ Roix, JM Bridger, K Kupper, KE Brown, L Andreozzi, M Cockell, M Costantini, M Neusser, N Gilbert, N Sadoni, NV Petrova, Patrizia Di Mare, PS Masny, S Boyle, S D’Antoni, S Saccone, S Saccone, S Saccone, S Saccone, Sabrina Tosi, Salvatore Saccone, SW Scherer, T Cremer, TS Furey, U Francke, WA Bickmore   +53 more
core   +1 more source

HiCognition: a visual exploration and hypothesis testing tool for 3D genomics

Genome Biology, 2023
Genome browsers facilitate integrated analysis of multiple genomics datasets yet visualize only a few regions at a time and lack statistical functions for extracting meaningful information.
Christoph C. H. Langer, Michael Mitter, Roman R. Stocsits, Daniel W. Gerlich   +3 more
doaj   +1 more source