Results 91 to 100 of about 5,043,774 (177)
Conservatoire des Données 3D SHS
, 2020 ” Le Conservatoire National des Données 3D SHS est un environnement de sauvegarde sécurisé pour les données 3D, soutenu par Huma-Num.. …
Consortium 3D SHS Team
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The Effect of Nuclear Perturbations on the 3D Organization of the Genome [PDF]
, 2020 Cells in our body experience constant mechanical forces that influence biological functions such as growth and development. The nucleus has been implicated as a key mechanosensor and can directly influence chromatin organization and epigenetic ...
Golloshi, Rosela
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3D-FISH analysis of the spatial genome organization in skin cells in situ
, 2020 NoSpatial genome organization in the cell nucleus plays a crucial role in the control of genome functions. Our knowledge about spatial genome organization is relying on the advances in gene imaging technologies and the biochemical approaches based on the
Fessing, Michael Y. +4 more
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Modeling and analysis of spatial genome organization
, 2019 Development of chromosome conformation capture (3C) and its derivative techniques such as Hi-C and ChIA-PET allow to capture the details of the genome organization on multiple scales and led to many new insights into the mechanisms of genome functioning.
SZALAJ, Przemek
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, 2020 Organization of chromatin in three-dimensional (3D) space impacts DNA-templated events by controlling the accessibility of transcriptional machinery to the underlying DNA sequence.
Robin Armstrong (8219674) +5 more
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3D GENOMIC ORGANIZATION OF MOUSE MACROPHAGES
, 2015 The spatial organization of the genome and its biological function are intimately linked. It is becoming evident that transcription regulation often involves multiple long-range regulatory elements and it?s influenced both by the genomic environment and by the shape of the genome.
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Dynamic Changes in DNA Replication Timing and 3D Genome Organization During Cardiac Differentiation
, 2023 University of Minnesota M.S. thesis. March 2023. Major: Biochemistry, Molecular Bio, and Biophysics. Advisor: Juan Carlos Rivera-Mulia. 1 computer file (PDF); vii, 35 pages.Genome architecture has emerged as a key factor of gene regulation and is tightly
Martinez Cifuentes, Santiago
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Inferential analysis of genomic 3D organization.
, 2014 DNA inside the nuclei of cells is folded into an intricate three-dimensional (3D) structure that influences how and when genes are turned on and off. For example, 3D interactions between distal regulatory elements, such as enhancers and their promoter targets are known to be responsible for regulating a range of genes with cell-type specific functions.
openaire +2 more sources
GeneRHi-C : 3D GENomE Reconstruction from Hi-C data
, 2019 Background: Many computational methods have been developedthat leverage the results from biological experiments (such as Hi-C)to infer the 3D organization of the genome. Formally, this is referredto as the 3D genome reconstruction problem (3D-GRP).
Kusalik, Anthony +2 more
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Genome MedicineBackground Three-dimensional (3D) chromatin architecture undergoes dynamic reorganization during mammalian gametogenesis and early embryogenesis.
Changliang Hou +25 more
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