Results 91 to 100 of about 4,825,767 (247)
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Analysis of expressed sequence tags (ESTs) from cat cerebrum and cerebellum cDNA librariesv
, 2005 The cat is an attractive candidate for an animal model for human disease, genome evolution, comparative research for several reasons. Although mouse and rat have been powerful models to examine molecular mechanisms of human hereditary disorders.
N. Yhuki, 김충곤, S. Obrien
core +1 more source
Advanced Engineering Materials, EarlyView.The OntOMat ontology establishes a structured framework for polymer matrix fiber reinforced composite materials, integrating manufacturing processes, characterization methods, and multiscale design through the VDI/VDE 3682 formalized process description standard.
Nicolas Christ +19 more
wiley +1 more source
Inter-chromosomal transcription hubs shape the 3D genome architecture of African trypanosomes
Nature CommunicationsThe eukaryotic nucleus exhibits a highly organized 3D genome architecture, with RNA transcription and processing confined to specific nuclear structures. While intra-chromosomal interactions, such as promoter-enhancer dynamics, are well-studied, the role
Claudia Rabuffo +10 more
doaj +1 more source
Analysis of 3D Genome Organization in 4-Cell Mouse Embryos
, 2023 Cell fate determination, which refers to how distinct types of signals interact with a cell to determine its fate and differentiation into a particular cell type, is a fundamental questions lying at the heart of developmental biology. Given that the type
Davarmanesh, Parmida
core
Physics‐Grounded Materials Artificial Intelligence for Reliable Materials Discovery
Advanced Functional Materials, EarlyView.Physics‐Grounded Materials AI (PhysMat AI) integrates physical priors, descriptors, constraints, verification, and data infrastructure into a unified full‐stack framework, enabling reliable, interpretable, and autonomous AI‐driven materials discovery.
Yuhang Wang +3 more
wiley +1 more source
[Article] 3D digital recording of archaeological, architectural and artistic heritage
, 2020 3D DIGITAL RECORDING OF ARCHAEOLOGICAL, ARCHITECTURAL AND ARTISTIC HERITAGE
Consortium 3D SHS Team
core
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
Nature Communications, 2019 Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.
Kyle Xiong, Jian Ma
doaj +1 more source