Results 201 to 210 of about 43,182 (237)

Temperature induced modulation of lipid oxidation and lipid accumulation in palmitate-mediated 3T3-L1 adipocytes and 3T3-L1 adipocytes

Journal of Thermal Biology, 2016
Human skin temperature can vary widely depending on anatomical location and ambient temperature. It is also known that local changes in skin and subcutaneous temperature can affect fat metabolism. This study aimed to explore the potential effects of surrounding thermal environment on fat by investigating cell viability, lipid oxidation, and lipid ...
Lin, Xiaofen, Li, Yi, Leung, Polly Hangmei, Li, Jiashen, Hu, Junyan, Liu, Xuan, Li, Zhi   +6 more
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The Effects of AICAR on Adipocyte Differentiation of 3T3-L1 Cells

Biochemical and Biophysical Research Communications, 2001
The AMP-activated protein kinase (AMPK) activator, 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), has been found to inhibit the differentiation of 3T3-L1 adipocytes, if added at an early phase of differentiation. AICAR blocks the expression of the late adipogenic markers, fatty acid synthase and acetyl-CoA carboxylase, and of the transcription ...
S A, Habinowski, L A, Witters
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Glucosamine-induced insulin resistance in 3T3-L1 adipocytes

American Journal of Physiology-Endocrinology and Metabolism, 2000
To study molecular mechanisms for glucosamine-induced insulin resistance, we induced complete and reversible insulin resistance in 3T3-L1 adipocytes with glucosamine in a dose- and time-dependent manner (maximal effects at 50 mM glucosamine after 6 h). In these cells, glucosamine impaired insulin-stimulated GLUT-4 translocation.
E, Heart, W S, Choi, C K, Sung
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Regulation of adipocyte differentiation of 3T3-L1 cells by PDZRN3

American Journal of Physiology-Cell Physiology, 2013
PDZRN3, a member of the PDZRN (or LNX) family of proteins, is essential for the differentiation of mesenchymal stem cells into myotubes, but it plays an inhibitory role in the differentiation of these cells into osteoblasts. Given that mesenchymal stem cells also differentiate into adipocytes, we examined the possible role of PDZRN3 in adipogenesis in
Takeshi, Honda, Aiko, Ishii, Makoto, Inui   +2 more
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MicroRNA-23a regulates 3T3-L1 adipocyte differentiation

Gene, 2016
MicroRNAs (miRNAs) are small, non-coding RNAs, which are involved in regulation of a variety of biological processes. Since previous studies regarding the role of miRNAs in the regulation of adipogenic differentiation have shown that miRNA-27a, one member of miRNA-23a∼27a∼24 cluster, could suppress adipogenesis.
Linyuan, Shen, Yi, Zhang, Jingjing, Du, Li, Chen, Jia, Luo, Xuewei, Li, Mingzhou, Li, Guoqing, Tang, Shunhua, Zhang, Li, Zhu   +9 more
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Activin B inhibits lipolysis in 3T3-L1 adipocytes

Biochemical and Biophysical Research Communications, 2010
Activin B, consisting of two inhibin betaB (INHBB) subunits, is a hormone known to affect gonadal function, reproduction and fetal development. We have reported that INHBB and activin B receptors are highly expressed in adipocytes suggesting that activin B may have local effects in adipose tissue.
Björn, Magnusson, Per-Arne, Svensson, Lena M S, Carlsson, Kajsa, Sjöholm   +3 more
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Nebivolol stimulates mitochondrial biogenesis in 3T3-L1 adipocytes

Biochemical and Biophysical Research Communications, 2013
Nebivolol is a third-generation β-adrenergic receptor (β-AR) blocker with additional beneficial effects, including the improvement of lipid and glucose metabolism in obese individuals. However, the underlying mechanism of nebivolol's role in regulating the lipid profile remains largely unknown.
Chenglin, Huang, Dongrui, Chen, Qihai, Xie, Ying, Yang, Weili, Shen   +4 more
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Glyburide action in cultured 3T3-L1 adipocytes.

Biochemistry international, 1986
During adipocyte differentiation of 3T3-L1 cells, glyburide increased the specific activity (mU/mg protein) of glycerol-3-P dehydrogenase (by at least 14-fold) and glutamine synthetase (by 5-fold). The glyburide-mediated increases in enzyme activities were greater in the presence than in the absence of insulin.
MILLER, RE, BHANDARI, B
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Effects of Capsaicin on Lipid Catabolism in 3T3‐L1 Adipocytes

Phytotherapy Research, 2010
AbstractCapsaicin (8‐methyl‐N‐vanillyl‐6‐nonenamide) is a pungent ingredient of red peppers, and has been reported to reduce body weight gain and adiposity in rodents. The present study investigated the effects of capsaicin on lipid catabolism in differentiated 3T3‐L1 adipocytes.
Mak-Soon, Lee, Chong-Tai, Kim, In-Hwan, Kim, Yangha, Kim   +3 more
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Effects of leptin on apoptosis and adipogenesis in 3T3-L1 adipocytes

Biochemical Pharmacology, 2007
Leptin has been demonstrated to induce adipose tissue apoptosis, which can contribute to the decrease of adiposity, after either central nervous system or peripheral administration. However, it is not known whether leptin acts only centrally to initiate a signal or can also act directly on adipocytes to induce apoptosis. The objective of this study was
Suresh, Ambati, Hye-Kyeong, Kim, Jeong-Yeh, Yang, Ji, Lin, Mary Anne, Della-Fera, Clifton A, Baile   +5 more
openaire   +2 more sources