Results 211 to 220 of about 259,851 (238)
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Effects of Capsaicin on Lipid Catabolism in 3T3‐L1 Adipocytes
Phytotherapy Research, 2010AbstractCapsaicin (8‐methyl‐N‐vanillyl‐6‐nonenamide) is a pungent ingredient of red peppers, and has been reported to reduce body weight gain and adiposity in rodents. The present study investigated the effects of capsaicin on lipid catabolism in differentiated 3T3‐L1 adipocytes.
Mak-Soon, Lee +3 more
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Effects of leptin on apoptosis and adipogenesis in 3T3-L1 adipocytes
Biochemical Pharmacology, 2007Leptin has been demonstrated to induce adipose tissue apoptosis, which can contribute to the decrease of adiposity, after either central nervous system or peripheral administration. However, it is not known whether leptin acts only centrally to initiate a signal or can also act directly on adipocytes to induce apoptosis. The objective of this study was
Suresh, Ambati +5 more
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Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes
The Journal of Nutritional Biochemistry, 2010Phosphorylated glucosamine (glucosamine-6-phosphate, PGlc) was synthesized using methanesulfonic acid, phosphorus pentoxide (P(2)O(5)), NH(2)NH(2) and DMF. Its inhibitory effect on lipid accumulation in cultured 3T3-L1 adipocytes was investigated by measuring triglyceride contents and Oil Red O staining.
Chang-Suk, Kong +3 more
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Salacia reticulata inhibits differentiation of 3T3-L1 adipocytes
Journal of Ethnopharmacology, 2011ETHOPARMACOLOGICAL RELEVANCE: Salacia reticulata, a herbal medicine which has been used for the treatment of early diabetes in Ayurvedic medicine, is reported to have an anti-obesity effect and to be useful in the treatment of diabetes mellitus, insulin resistance and other metabolic diseases.The present study was performed to elucidate the mechanism ...
Tsutomu, Shimada +8 more
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3T3-L1 Adipocytes promote the growth of mammary epithelium
Experimental Cell Research, 1984Murine mammary epithelium grows in association with predominantly adipocyte stroma in vivo. To investigate potential growth-promoting effects of adipocytes on mammary epithelium, we developed a co-culture system of mammary epithelium and adipocytes by taking advantage of the 3T3-L1 cell line.
Levine, J F, Stockdale, F E
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Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes
Biochemical and Biophysical Research Communications, 2007Nobiletin is a polymethoxylated flavone found in certain citrus fruits. Here we demonstrate that nobiletin enhance differentiation of 3T3-L1 preadipocytes. Nobiletin dose-dependently increased accumulation of lipid droplets in adipocytes. Quantitative RT-PCR analyses indicated that nobiletin increased the expression of genes critical for acquisition of
Takeshi, Saito +2 more
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ATF3 inhibits adipocyte differentiation of 3T3-L1 cells
Biochemical and Biophysical Research Communications, 2012ATF3 is a stress-adaptive gene that regulates proliferation or apoptosis under stress conditions. However, the role of ATF3 is unknown in adipocyte cells. Therefore, in this study, we investigated the functional role of ATF3 in adipocytes. Both lentivirus-mediated overexpression of ATF3 and stably-overexpressed ATF3 inhibited adipocyte differentiation ...
Min Kyung, Jang +3 more
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Endothelin-1 induces lipolysis in 3T3-L1 adipocytes
American Journal of Physiology-Endocrinology and Metabolism, 2005Endothelin-1 (ET-1) affects glucose uptake in adipocytes and may play an important role in adipose physiology. One of the principal functions of adipose tissue is the provision of energy substrate through lipolysis. In the present study, we investigated the effects of ET-1 on lipolysis in 3T3-L1 adipocytes.
Chi-Chang, Juan +3 more
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Raloxifene promotes adipocyte differentiation of 3T3-L1 cells
European Journal of Pharmacology, 2006To explore the possibility that raloxifene might influence an adipocyte differentiation and lipogenesis, we studied the effects of raloxifene on the expression of adiponectin and other peroxisome proliferator-activated receptor gamma targeting genes using the 3T3-L1 adipocytes. With standard adipogenic inducers, we added raloxifene at various doses for
Yuko, Murase +7 more
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Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes
American Journal of Physiology-Cell Physiology, 1984The role of polyamines in the differentiation of 3T3-L1 fibroblasts into adipose cells was studied. This conversion was blocked by the addition of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, which prevented a rise in spermidine content in the differentiating cells.
B G, Erwin, D R, Bethell, A E, Pegg
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