Results 141 to 150 of about 4,980,683 (248)

SL-176 significantly reduced the size of lipid droplets in 3T3-L1 cells.

open access: yes, 2019
After treatment of SL-176 during adipocyte differentiation (from Day0 to Day8), lipid droplets in differentiated 3T3-L1 cells on Day 8 were stained by Monodansylpentane. Scale bar = 10 μm.
Kazuyasu Sakaguchi (1272375)   +4 more
core   +1 more source

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

open access: yesCancer Science, Volume 117, Issue 11, Page 3007-3021, November 2026.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon   +6 more
wiley   +1 more source

Inhibition of fats accumulation in 3T3-L1 cells via suppression of adipogenesis and lipogenesis by AnT Fr.

open access: yes, 2018
3T3-L1 pre-mature cells were allowed to proliferate in DMEM media in the presence (various concentrations) and absence (control) of ELECk. the lipid droplets accumulated in mature 3T3-L1 cell were observed with the help of a phase contrast inverted ...
Jin Hyuk Shin (6058469)   +5 more
core   +1 more source

Cargo Stability of Extracellular Vesicles Derived From Non‐Diseased Sources: Effects of Storage and Handling Conditions

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi   +7 more
wiley   +1 more source

Effects of demethylation on leptin expression in 3T3-L1 cells.

open access: yes, 2016
A, B: Promoter methylation (A) and leptin expression (B) in 3T3-L1 pre-adipocytes treated with 0.5 or 5 μM 5-azacytidine for 7 days. C, D: Promoter methylation (C) and leptin expression (D) in adipocytes derived from 3T3-L1 precursors treated with or ...
Yumiko Miyatake (3142293)   +10 more
core   +1 more source

Nicotinamide inhibits adipocyte differentiation of 3T3‐L1 cells

open access: yesFEBS Letters, 1982
Lewis, Janet E.   +2 more
openaire   +2 more sources

IL-33 regulates adipogenesis via Wnt/β-catenin/PPAR-γ signaling pathway in preadipocytes

open access: yesJournal of Translational Medicine
Interleukin-33 (IL-33), an emerging cytokine within the IL-1 family, assumes a pivotal function in the control of obesity. However, the specific mechanism of its regulation of obesity formation remains unclear. In this study, we found that the expression
Danning Xu   +9 more
doaj   +1 more source

Representative immunoblots of NF-κB activation in 3T3-L1 preadipocytes and mature adipocytes.

open access: yes, 2014
3T3-L1 cells were treated with LPS (10 ng/ml); Palmitic acid (0.5 mM); Myristic acid (0.5 mM); and Oleic acid (0.5 mM) for 0, 1 and 2 h. Phosphorylation levels of p65 (Ser536) relative to total p65; and total levels of IκBα relative to α-tubulin were ...
Aimee L. Dordevic (575119)   +2 more
core   +1 more source

Representative immunoblots of MAPK phosphorylation in 3T3-L1 preadipocytes and mature adipocytes.

open access: yes, 2014
3T3-L1 cells were treated with LPS (10 ng/ml); Palmitic acid (0.5 mM); Myristic acid (0.5 mM); and Oleic acid (0.5 mM) for 0, 1 and 2 h. Phosphorylation levels of p38 (Thr180/Tyr182) relative to total p38; and phosphor-JNK (Thr183/Tyr185) relative to ...
Aimee L. Dordevic (575119)   +2 more
core   +1 more source

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