Results 131 to 140 of about 4,980,683 (248)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, Volume 38, Issue 61, 2 November 2026.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Effect of MGO on inflammation in 3T3-L1 cells

MaRBLe, 2016
Advanced Glycation Endproducts (AGEs) play a major role in inducing adipose tissue inflammation associated with obesity-associated insulin resistance. MGO, a precursor for AGEs is accumulated during obesity. Therefore we hypothesized that increased MGO-derived AGEs induce inflammation in adipose tissue via the interaction with RAGE.
openaire   +2 more sources

INFLUENCE OF 5,7-DIMETHOXY COUMARIN ON ADIPOGENESIS IN HIGH GLUCOSE INDUCED INSULIN RESISTANT 3T3-L1 ADIPOCYTES [PDF]

Insulin resistance in adipocytes disrupts whole-body metabolic homeostasis contributing to various complications. This study investigates the adipogenic potential of 5,7-dimethoxy Coumarin (5,7-DMC) in high glucose-induced insulin resistance in 3T3-L1 ...
J. JOHN ROBERT, C. SANKARANARAYANAN, R. SARUMATHI   +2 more
core   +1 more source

Optical‐Field Engineering and Instrumentation in Brillouin Microscopy

Advanced Photonics Research, Volume 7, Issue 11, November 2026.
Brillouin microscopy provides label‐free mechanical contrast through gigahertz light–acoustic interactions. This Review examines how optical‐field engineering and instrument architecture shape spectral precision, acquisition throughput, background rejection, spatial performance, and optical exposure.
Kangwen Tong, Feihong Lin, Xiaoyu Yang, Emiliano Descrovi, Xu Liu, Qing Yang   +5 more
wiley   +1 more source

Notch-1 expression levels in 3T3-L1 cells influences ras signaling and transformation by oncogenic ras

, 1999
Notch proteins participate in interactions between several cell types involved on the specification of numerous cell fates during development. We previously showed that enforced downregulation of Notch-1 expression prevented adipogenesis of 3T3-L1 cells.
Ruiz Hidalgo, María José, Garcés, Carmen, Laborda Fernández, Jorge   +2 more
core   +1 more source

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang, Jinqin Wei, Zhao Jiang, Yingming Luo, Yan Zhou, Jiafan Yang, Hui Cui   +6 more
wiley   +1 more source

Coculture with BJ fibroblast cells inhibits the adipogenesis and lipogenesis in 3T3-L1 cells

, 2010
Mouse or human fibroblasts are commonly used as feeder cells to prevent differentiation in stem or primary cell culture. In the present study, we addressed whether fibroblasts can affect the differentiation of adipocytes.
박상욱, Sang-Kyu Park, Hyun Jeong Jeong, Dojun Yoon, Sahng Wook Park, Hojeong Kim   +5 more
core   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8298-8314, November 2026.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Expression of T1Rs during differentiation of 3T3-L1 cells.

, 2013
A. The total RNAs prepared from 3T3-L1 cells at the indicated time points during differentiation were subjected to quantitative RT-PCR using mouse ribosomal protein S18 as an internal control as described in`Materials and Methods'.
Yoritsuna Yamamoto (288678), Hiroshi Shibata (288684), Tadahiro Kitamura (288676), Itaru Kojima (288682), Tsutomu Sasaki (161991), Yosuke Masubuchi (288668), Yuko Nakagawa (288670), Jinhui Ma (288674), Hitoshi Kurose (288680)   +8 more
core   +1 more source

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

Obesity, Volume 34, Issue 11, Page 2124-2134, November 2026.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi, Celeste Lauriola, Cristina Caccioppoli, Rossella D'Oria, Nicola Marrano, Giuseppina Biondi, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino, Angelo Cignarelli   +10 more
wiley   +1 more source