Results 121 to 130 of about 4,980,683 (248)

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, Volume 46, Issue 12, Page 4264-4287, December 2026.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Phosphatidylcholine causes adipocyte-specific lipolysis and apoptosis in adipose and muscle tissues.

PLoS ONE, 2019
Phosphatidylcholine (PPC) formula has been therapeutically used to reduce areas of localized fat. However, no single research has been carried out on its effect on a variety of cells in adipose and muscle tissues.
Tae Woo Jung, Taekwang Park, Jinwoo Park, Uiseok Kim, Hyun Dong Je, Hyeong-Dong Kim, Seong-Wan Cho, A M Abd El-Aty, Jin-Ho Song, Hyoung-Chun Kim, Yong Kyoo Shin, Ji Hoon Jeong   +11 more
doaj   +1 more source

Efectos de la modulación de los receptores PPAR? y de Glucocorticoides en la expresión de Caveolina-1 en células 3T3-L1 [PDF]

, 2011
Caveolina-1es una proteína con un importante papel en el tejido adiposo, donde participa en la respuesta a insulina y el metabolismo de lípidos. La expresión de Caveolina-1 aumenta durante la adipogénesis de células 3T3-L1, pero se desconocen los ...
Domínguez Moré, Gina Paola
core  

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, Volume 27, Issue 12, December 2026.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

3T3-L1 adipocytes display phenotypic characteristics of multiple adipocyte lineages

, 2015
Differentiated 3T3-L1 adipocytes are a widely used in vitro model of white adipocytes. In addition to classical white and brown adipocytes that are derived from different cell lineages, beige adipocytes have also been identified, which have ...
Sean Mcgee (13095276), Shona Morrison (13094544)   +1 more
core  

MTP location in differentiated 3T3-L1 cells.

, 2015
(A) 3T3-L1 cells were differentiated for 6 days, fixed and stained with antibodies to MTP (red) and perilipin (PLIN) 2 (green) and appropriate secondary antibodies and examined by confocal microscopy.
Carla M. Harris (782761), Larry L. Swift (782762), Delia B. Robinson (782760), Peter J. Mohler (35301), Takashi Suzuki (8491), W. Gray Jerome (278551), Joyce E. Johnson (483069), Joseph D. Love (782759)   +7 more
core   +1 more source

Marine‐Derived Type I Collagen From Scyliorhinus canicula : Extraction, Characterization, and Biomedical Applications

Journal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
Marine‐derived type I collagen is extracted from Scyliorhinus canicula skin and characterized by physicochemical and morphological analyses. The collagen exhibits excellent biocompatibility, promotes wound healing, reduces inflammatory mediators, and inhibits melanogenesis.
Marwa Rejeb, Aida Lahmar, Arem Selmi, Tahsine Kosksi, Nawres Debbabi, Ghania Hamdi‐Degobert, Leila Chekir‐Ghedira   +6 more
wiley   +1 more source

Change of expression of proteins associated with adipogenesis in baicalein-treated 3T3-L1 cells.

, 2016
3T3-L1 cells were differentiated as described in Fig 2A. Protein levels were detected by Western blot analysis using cell extracts (15 μg/lane).
Hideto Yoshihara (3138798), Ko Fujimori (308511), Yukari Nakao (3138795)   +2 more
core   +1 more source

Shikonin: From Biosynthesis and Pharmacological Mechanisms to Translational Safety and Drug Delivery

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
Shikonin, biosynthesised in Boraginaceae roots from phenylalanine‐derived PHB and isoprenoid GPP, modulates redox balance, cellular stress, signalling pathways, and regulated cell death. Preclinical studies support diverse pharmacological activities, while nanocarriers improve dispersion and delivery.
Namini Joshi, Prabhakar Semwal, Balwant Rawat, Ravendra Kumar, Mozaniel Santana de Oliveira, Nishant Rai, Janhvi Mishra Rawat   +6 more
wiley   +1 more source

Effect of PHB knockdown on the morphology of mitochondria in 3T3-L1 cells.

, 2012
3T3-L1 cells were transfected with siRNA targeting PHB1 or PHB2, and cultured for three days. siControl was used as the control. A. The cristae morphology of mitochondria (arrows) in 3T3-L1 cells, transfected with the indicated siRNAs, was assessed by ...
Ting Kang (174410), Yiming Lin (174403), Wei Xu (28953), Y. Eugene Chen (122573), Winston E. Thompson (174423), Bo Huang (30906), Moshood Olatinwo (174418), Minerva Garcia-Barrio (174416), Roland Matthews (174421), Dong Liu (115204)   +9 more
core   +1 more source