Results 41 to 50 of about 4,980,683 (248)

Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells [PDF]

Amino Acids, 2011
Polyamines spermidine and spermine are known to be required for mammalian cell proliferation and for embryonic development. Alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC) a limiting enzyme of polyamine biosynthesis, depleted the cellular polyamines and prevented triglyceride accumulation and differentiation in 3T3 ...
Ishii, Ikumi, Ikeguchi, Yoshihiko, Mano, Hiroshi, Wada, Masahiro, Pegg, Anthony E., Shirahata, Akira   +5 more
openaire   +2 more sources

Antioxidant and Wound Healing Property of Gelsolin in 3T3-L1 Cells [PDF]

Oxidative Medicine and Cellular Longevity, 2020
Delineation of factors which affect wound healing would be of immense value to enable on-time or early healing and reduce comorbidities associated with infections or biochemical stress like diabetes. Plasma gelsolin has been identified earlier to significantly enable injury recovery compared to placebo.
Bhavna Vaid, Bhupinder Singh Chopra, Sachin Raut, Amin Sagar, Maulik D. Badmalia, null Ashish, Neeraj Khatri   +6 more
openaire   +2 more sources

Anti-Obesity Effect of α-Cubebenol Isolated from Schisandra chinensis in 3T3-L1 Adipocytes

Biomolecules, 2021
The efficacy of α-cubebenol isolated from Schisandra chinensis has been studied in several diseases, including cecal ligation, puncture challenge-induced sepsis, and degranulation of neutrophils.
Su Jin Lee, Ji Eun Kim, Yun Ju Choi, Jeong Eun Gong, You Jeong Jin, Da Woon Lee, Young Whan Choi, Dae Youn Hwang   +7 more
doaj   +1 more source

Novel Self-Nanoemulsifying Drug Delivery System of Single Bulb Garlic: Stability, Toxicity, and Antiinflammation in 3T3-L1 Cells

Science and Technology Indonesia, 2022
Single bulb garlic (SBG) has the potential as an immunomodulator; however, it has low solubility and bioavailability. A lipid-based delivery system, that is, the self-nanoemulsifying drug delivery system (SNEDDS), offers a novel opportunity in drug ...
Dewi Sekar Miasih , Yuslinda Annisa, Sri Rahayu Lestari , Hendra Susanto , Sunaryono   +4 more
doaj   +3 more sources

Antidiabetic effect of combination of fractionated-extracts of Andrographis paniculata and Centella asiatica: In vitro study

Asian Pacific Journal of Tropical Biomedicine, 2018
Objective: To examine the effect of combination of Andrographis paniculata herb fraction (AHF) and Centella asiatica herb fraction (CHF) on PPARγ and GLUT4 mRNA expressions in 3T3-L1 adipocyte, and its effect on insulin-stimulated glucose uptake. Methods:
LOM. Fitrawan, R Ariastuti, R R Tjandrawinata, A E Nugroho, S Pramono   +4 more
doaj   +1 more source

Differentiation of 3T3-L1 cells.

, 2016
Lipoprotein lipase (lpl) expression during the differentiation process of 3T3-L1 cells.
Allan Stensballe (293505), Steen B. Pedersen (331604), Toke P. Kroager (3149895), Bjørn Richelsen (844955), Kristian W. Sanggaard (110149), Jan J. Enghild (110183), Anders D. Knudsen (3149898), Mark K. Nøhr (844950), Jens Ølholm (3149892)   +8 more
core   +1 more source

Characteristics of 3T3-L1 cells with overexpressed Brd2.

, 2013
3T3-L1 cells transfected with pmBrd2 and control (pcDNA3.1), respectively. (A) Adipogenic differentiation of 3T3-L1 adipocytes from pre-adipocytes and Oil Red O staining on day 4 of treatment reveals lipids in cells that have undergone differentiation ...
Jingyu Wang (292122), Min Yu (120607), Miaofang Dong (475610), Fangnian Wang (475613), Xiaoxia Liu (294088), Kun Zang (475609), Yuxiong Wang (152709), Yimin Li (475612), Ruixin Sun (475611), Yinong Huang (312166)   +9 more
core   +1 more source

Macrostemonoside A Promotes Visfatin Expression in 3T3-L1 Cells

Biological and Pharmaceutical Bulletin, 2007
The newly identified fat cell-secreted factor, visfatin, is insulin-mimetic and play a positive role in attenuating insulin resistance and diabetes. Natural steroidal saponins including tigogenin saponins have been reported to provide anti-diabetic activity and modulate glucose metabolism, but the mechanism remains unknown.
Zhou, Hua, Yang, Xi, Wang, Nai-li, Zhang, Ya-ou, Cai, Guo-ping   +4 more
openaire   +3 more sources

Characteristics of 3T3-L1 cells with Brd2 knockdown.

, 2013
3T3-L1 cells were transfected with Brd2 shRNA (SiBrd2) or scramble shRNA (SiC) plasmids respectively. (A) Adipogenic differentiation of 3T3-L1 adipocytes from pre-adipocytes and Oil Red O staining on day 4 of treatment reveals lipids in cells that have ...
Jingyu Wang (292122), Min Yu (120607), Miaofang Dong (475610), Fangnian Wang (475613), Xiaoxia Liu (294088), Kun Zang (475609), Yuxiong Wang (152709), Yimin Li (475612), Ruixin Sun (475611), Yinong Huang (312166)   +9 more
core   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source