Results 51 to 60 of about 4,980,683 (248)
Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells [PDF]
, 2018 Start domain-containing protein 3 (Stard3) plays roles in intracellular cholesterol distribution, however, the role of Stard3 in the adipogenesis of 3T3-L1 preadipocytes remains unclear.
Ruan, XZ +4 more
core +1 more source
TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activitys⃞
Journal of Lipid Research, 2008 In the course of an effort to identify the regulators for peroxisome proliferator-activated receptor γ (PPARγ)-dependent perilipin gene expression, we found that tribbles homolog 3 (TRB3), containing a single kinase domain without enzymatic activity ...
Yu Takahashi +3 more
doaj +1 more source
Advanced Science, EarlyView.As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia +13 more
wiley +1 more source
Brd2 inhibits adipogenesis via the ERK1/2 signaling pathway in 3T3-L1 adipocytes.
PLoS ONE, 2013 Bromodomain-containing protein 2 (Brd2) is a nuclear serine/threonine kinase involved in transcriptional regulation. In 3T3-L1 adipocytes, Brd2 normally co-represses PPARγ (peroxisome proliferator-activated receptor gamma) and inhibits adipogenesis. Here,
Kun Zang +9 more
doaj +1 more source
Expression of VPAC/PAC receptors in 3T3-L1 cells during differentiation of 3T3-L1 cells.
, 2013 A. qPCR analysis of the mRNA expression of VPAC/PAC receptors in 3T3-L1 two days post-confluent cells (day 0) and during differentiation till day 9.
Elodie Courtequisse (455776) +6 more
core +1 more source
Representative images of ORO-stained and Nile Red-stained 3T3-L1 cells differentiated.
, 2022 (A) ORO staining of differentiated 3T3-L1 adipocytes. (a) Normal group. (b) 3T3-L1 cells were treated with differentiation medium. (c) 3T3-L1 cells were treated with cistanche of Boiled. (d) 3T3-L1 cells were treated with cistanche of Enzymed. (e) 3T3-L1
Le Su (276777) +9 more
core +1 more source
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
Aspirin Breaks the Crosstalk between 3T3-L1 Adipocytes and 4T1 Breast Cancer Cells by Regulating Cytokine Production. [PDF]
PLoS ONE, 2016 Breast cancer is one of the most common cancers in women worldwide. The obesity process is normally accompanied by chronic, low-grade inflammation. Infiltration by inflammatory cytokines and immune cells provides a favorable microenvironment for tumor ...
Chia-Chien Hsieh, Yu-Shan Huang
doaj +1 more source
Advanced Science, EarlyView.A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian +14 more
wiley +1 more source
Induction of Beige-Like Adipocytes in 3T3-L1 Cells
Journal of Veterinary Medical Science, 2014 There are two types of brown adipocytes: classical brown adipocytes that form the brown fat depots and beige adipocytes that emerge in the white fat depots. Beige adipocytes have a low level of uncoupling protein 1 (Ucp1) expression in the basal state, but Ucp1 expression is increased in response to β adrenergic receptor activation.
ASANO, Hiroki +6 more
openaire +3 more sources