Results 71 to 80 of about 4,980,683 (248)

3T3-L1 adipocyte differentiation.

open access: yes, 2016
(A) Phase contrast images of 3T3-L1 cells from induction (day 0) to ten days post-induction. Cells initially display a fibroblast phenotype. Over the course of differentiation, cell morphology changes and cells accumulate lipid droplets internally.
Nicholas Marze (841739)   +2 more
core   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

open access: yesJSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed   +5 more
wiley   +1 more source

Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation

open access: yesJournal of Lipid Research, 2011
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that exerts insulinotropic and growth and survival effects on pancreatic β-cells.
Su-Jin Kim   +2 more
doaj   +1 more source

Inhibitory effects of Porphyra dentata extract on 3T3-L1 adipocyte differentiation

open access: yesJournal of Animal Science and Technology, 2020
This study was aimed to investigate the inhibitory effects of Porphyra dentata (P. dentata) extract on the adipogenesis of 3T3-L1 cells and evaluate its anti-obesity effect. The proliferation of
Su-Young Choi   +5 more
doaj   +1 more source

Suppression of inflammatory response by adenovirus-mediated overexpression of Ephrin-B1 in 3T3-L1 adipocytes.

open access: yes, 2013
CAR-3T3-L1 preadipocytes and adipocytes were infected with adenovirus expressing Ephrin-B1 (Ad-EfnB1) or β-galactosidase (Ad-βgal). CAR-3T3-L1 adipocytes were transfected with Ad-EfnB1 or Ad-βgal on day 7 after differentiation and cocultured with RAW264 ...
Yu Tsushima (465409)   +11 more
core   +1 more source

Anti‐hypercholesterolemic effects of barley and its role in the management of metabolic disorders: A comprehensive review

open access: yesJSFA reports, EarlyView.
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid   +8 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Preliminary Evidence for Adipocytokine Signals in Skeletal Muscle Glucose Uptake

open access: yesFrontiers in Endocrinology, 2018
The cross talk between the adipose tissue and insulin target tissues is a key mechanism for obesity-associated insulin resistance. However, the precise role of the interaction between the skeletal muscle and adipose tissue for insulin signaling and ...
Akihiro Kudoh   +4 more
doaj   +1 more source

Seipin-A212P inhibits adipogenesis in 3T3-L1 cells.

open access: yes, 2013
(A) A schematic diagram of the constructs used in generating the two stable 3T3-L1 cell lines expressing wild type Seipin (3T3-WT) or A212P mutant (3T3-A212P).
Kenneth Wee (387154)   +6 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

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