Results 91 to 100 of about 4,980,683 (248)
Phytotherapy Research, EarlyView.CA directly binds to and activates AMPK to suppress NLRP3/GSDMD signaling, thereby alleviating hepatocyte pyroptosis in T2DM mice. ABSTRACT Type 2 diabetes mellitus (T2DM) is frequently accompanied by chronic ethanol (ET) consumption, which worsens metabolic dysregulation and organ damage.
Huaiying Tang +13 more
wiley +1 more source
Current Issues in Molecular BiologyHomeodomain-interacting protein kinase 2 (HIPK2) is an important regulator of various transcription factors and cofactors, which are involved in cell growth, cell death, and embryonic development.
Anil Kumar Yadav +3 more
doaj +1 more source
Inhibitory Effects of Ethyl Acetate-Soluble Fraction from on Lipid Accumulation in 3T3-L1 Cells
Natural Product Communications, 2013 Fruits of mulberry ( Morus alba ) have been widely used for therapeutic purposes in Asian countries for centuries. Treatment of 3T3-L1 cells with ethanolic extracts of M. alba decreased adipocyte differentiation at 100 μg/mL by 18.6%.
Hee-Sook Park, Soon-Mi Shim, Gun-Hee Kim
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Phytotherapy Research, EarlyView.Magnoflorine ameliorates metabolic dysfunction‐associated steatohepatitis by promoting AMPKα‐mediated lipophagy and fatty acid oxidation. ABSTRACT Emerging as a significant clinical burden, metabolic dysfunction‐associated steatohepatitis (MASH) continues to challenge global healthcare systems due to limited effective interventions.
Zhengjie Lu +6 more
wiley +1 more source
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells
Diabetes, Metabolic Syndrome and Obesity, 2021 Rensiqin Wu,1 Hui Wang,1 Jian Huangfu,1 Rui Xiao2 1Department of Endocrinology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, Inner Mongolia, People’s Republic of China; 2Key Laboratory of Molecular Pathology, Inner ...
Wu R, Wang H, Huangfu J, Xiao R
doaj
Smart Molecules, EarlyView.Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li +10 more
wiley +1 more source
Cellular location of MTP in basal 3T3-L1 cells.
, 2015 (A) 3T3-L1 cells were grown in chamber slides and prior to reaching confluence, the cells were fixed and stained as indicated. MTP staining in the juxtanuclear region of the cells co-localizes with GBF1, but does not co-localize with the ER marker GRP78.
Carla M. Harris (782761) +7 more
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Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Frontiers in Physiology, 2019 ObjectiveGhrelin is a 28-amino-acid peptide that regulates energy hemostasis, glucose and lipid metabolism. We aimed to explore the effects of ghrelin on the proliferation and differentiation of 3T3-L1 and human primary preadipocytes.Methods3-(4,5 ...
Hui Miao +5 more
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Adipocyte, 2020 Hyperinsulinemia is the hallmark of the development of insulin resistance and precedes the diagnosis of type 2 diabetes. Here we evaluated the effects of prolonged exposure (≥4 days) to high insulin doses (150 nM) in vitro in two adipose cell types ...
A. Rossi +7 more
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