Results 21 to 30 of about 4,980,683 (248)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Multiple biotin-containing proteins in 3T3-L1 cells [PDF]
Biochemical Journal, 1986 Extracts of 3T3-L1 cells prepared after labelling the monolayer cultures with [3H]biotin contained numerous protein bands that were detected by fluorography of dried SDS/polyacrylamide electrophoresis gels. All labelled proteins in the extracts could be removed by avidin affinity chromatography. The biotin-containing subunits of acetyl-CoA carboxylase,
C S, Chandler, F J, Ballard
openaire +2 more sources
Oleate induces apoptosis in 3T3-L1 adipocytes [PDF]
, 2011 Oleic acid (C18:1) play an important role in proliferation of fat cells. In this study, the effect of oleate on cells viability in 3T3-L1 cells (fat cells) was investigated.
Rohana, Abu +2 more
core +2 more sources
The 3T3-L1 cell under optical microscope.
, 2022 The figure of 3T3-L1 cells in pre-staining. (A) Normal group. (B) 3T3-L1 cells were treated with differentiation medium. (C) 3T3-L1 cells were treated with cistanche of Boiled. (D) 3T3-L1 cells were treated with cistanche of Enzymed.
Le Su (276777) +9 more
core +1 more source
Adipocyte, 2021 Cell lines recapitulating physiological processes can represent alternatives to animal or human studies. The 3T3-L1 cell line is used to mimic adipocyte function and differentiation. Since transfection of 3T3-L1 cells is difficult, we used a modified 3T3-
Tomás Suchý +6 more
doaj +1 more source
Overexpression of AFF4 in 3T3-L1 cells.
, 2022 (A, B) Western blot and RT-qPCR analysis of AFF4 expression in Ctrl, oeScram and oeAFF4 in 3T3-L1 cells. (C) CCK8 assay of 3T3-L1 cells proliferation. n = 6. All quantified data are presented by as mean ± SD. The P values were calculated by one-way ANOVA
Weimin Lin (2117626) +11 more
core +1 more source
Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells
FEBS Open Bio, 2020 Dysregulation of adipocyte differentiation and dysfunction play key roles in the pathogenesis of obesity and associated disorders such as diabetes and metabolic syndrome, and as such, a better understanding of the molecular mechanism of adipogenesis may ...
Tomiyasu Murata +7 more
doaj +1 more source
Simple Analysis of Lipid Inhibition Activity on an Adipocyte Micro-Cell Pattern Chip
Biomolecules, 2018 Polydimethyl-siloxane (PDMS) is often applied to fabricate cell chips. In this study, we fabricated an adipocyte microcell pattern chips using PDMS to analyze the inhibition activity of lipid droplets in mouse embryo fibroblast cells (3T3-L1) with anti ...
Gi Yong Kim +5 more
doaj +1 more source
High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells. [PDF]
PLoS ONE, 2011 BACKGROUND: High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insulin secretion in type 2 diabetes patients. This investigation was designed to determine the effects and mechanisms of HDL on glucose uptake in adipocytes ...
Qichun Zhang +8 more
doaj +1 more source
Increased Oxidative Stress in Cultured 3T3-L1 Cells was Attenuated by Berberine Treatment
Natural Product Communications, 2015 The 3T3-L1 cell line is one of the most well-characterized and reliable models for studying adipocytes. Increased oxidative stress in accumulated fat was found in 3T3-L1 cells.
Shi-Fen Dong +5 more
doaj +1 more source