Results 11 to 20 of about 4,980,683 (248)
Adenovirus transduction of 3T3-L1 cells [PDF]
Journal of Lipid Research, 2001 3T3-L1 cells offer an excellent model system for studies of differentiation and biochemistry of fat cells. However, these cells are limited in their utility by the low efficiency with which DNA can be introduced by transfection.
David J. Orlicky, Jerome Schaack
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Angiotensinogen gene expression in 3T3-L1 cells
American Journal of Physiology-Cell Physiology, 1989 It has previously been established that angiotensinogen mRNA is present in brown and white adipose tissue of the rat. To determine whether angiotensinogen gene expression is present in adipocytes as compared with other cell elements, we have examined angiotensinogen mRNA in 3T3-L1 cells.
J A, Saye +4 more
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Biomedical PapersBackground. Obesity and related metabolic diseases are becoming a worldwide epidemic, leading to increased mortality and heavy medical costs. Our Chinese herbal formula Xiao-Gao-Jiang-Zhuo (XGJZ) has remarkable effects on curing obese patients in the ...
Liang Chen +5 more
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Phosphatidylcholine induces apoptosis of 3T3-L1 adipocytes [PDF]
Journal of Biomedical Science, 2011 Background Phosphatidylcholine (PPC) formulation is used for lipolytic injection, even though its mechanism of action is not well understood. Methods The viability of 3T3-L1 pre-adipocytes and differentiated 3T3-L1 cells was measured after treatment of ...
Li Hailan +8 more
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European Journal of Histochemistry, 2013 The 3T3-L1 cell line, derived from 3T3 cells, is widely used in biological research on adipose tissue. 3T3-L1 cells have a fibroblast-like morphology, but, under appropriate conditions, they differentiate into an adipocyte-like phenotype.
V. Rizzatti +5 more
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Isorhamnetin Represses Adipogenesis in 3T3‐L1 Cells [PDF]
Obesity, 2009 Adipocyte dysfunction is strongly associated with the development of obesity, which is a major risk factor for many disorders including diabetes, hypertension, and heart disease. It is generally accepted that the regulation of adipogenesis or adipokines expression prevents obesity.
Jongsung, Lee +9 more
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Inhibition of adipogenesis by Tempol in 3T3-L1 cells [PDF]
Free Radical Biology and Medicine, 2010 Obesity is highly associated with an increased risk of serious health conditions including hypertension, cardiovascular disease, diabetes, and cancer. Changes in redox status with increased oxidative stress have been linked with obesity. Previous studies have shown that administration of the antioxidant Tempol in the food of mice prevents obesity ...
Yuval, Samuni +6 more
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Regulation of pyruvate carboxylase in 3T3-L1 cells [PDF]
Biochemical Journal, 1995 When 3T3-L1 fibroblasts differentiate to adipocytes, the specific activity of pyruvate carboxylase (PC) increases about 25-fold in parallel with its intracellular protein concentration. The increase in PC protein concentration is accompanied by a 9-10-fold increase in the relative abundance of 4.2 kb PC mRNA measured by Northern-blot analysis using a ...
J, Zhang, W L, Xia, F, Ahmad
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Sclerostin Enhances Adipocyte Differentiation in 3T3‐L1 Cells [PDF]
Journal of Cellular Biochemistry, 2016 ABSTRACTSclerostin, a secreted protein encoded by the Sost gene, is produced by osteocytes and is inhibited by osteoblast differentiation and bone formation. Recently, a functional association between bone and fat tissue has been suggested, and a correlation between circulating sclerostin levels and lipid metabolism has been reported in humans. However,
Ukita, Mayumi +3 more
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EPAS1 Promotes Adipose Differentiation in 3T3-L1 Cells [PDF]
Journal of Biological Chemistry, 2004 Adipose differentiation is regulated by several transcription factors, such as the CAAT/enhancer-binding protein family and peroxisome proliferator activator (PPAR) gamma2. Several recent studies have shown that the basic helix-loop-helix-PAS superfamily is also involved in the regulation of adipose differentiation.
Shigeki, Shimba +3 more
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