Results 231 to 240 of about 4,897,037 (304)

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8298-8314, November 2026.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

LSD1-mediated demethylation of the DNA damage response factor ATM promotes senescence and organ aging. [PDF]

J Clin Invest
Zhang Y, Yu C, Zhang X, Li LX, Cheng AS, Li X.   +5 more
europepmc   +1 more source

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

Obesity, Volume 34, Issue 11, Page 2124-2134, November 2026.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi, Celeste Lauriola, Cristina Caccioppoli, Rossella D'Oria, Nicola Marrano, Giuseppina Biondi, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino, Angelo Cignarelli   +10 more
wiley   +1 more source

Adipocyte-derived estrogen signaling influences TROP2 expression in ERα-positive breast cancer. [PDF]

Front Endocrinol (Lausanne)
Gelsomino L, Manna L, Marchio V, Del Console P, Augimeri G, Giordano C, Győrffy B, Bonofiglio D, De Angelis C, Catalano S, Barone I.   +10 more
europepmc   +1 more source

Graphitic Carbon Nitride‐Based Microrobots: Progress and Prospects in Environmental and Biomedical Applications

Small, Volume 22, Issue 62, 6 November 2026.
This Review summarizes recent progress in g‐C3N4‐based microrobots, including fabrication strategies for different morphologies and their main propulsion mechanisms. Their applications in environmental remediation and biomedicine, including water purification, antibacterial therapy, and drug delivery, are discussed.
Yunhuan Yuan, Martin Pumera
wiley   +1 more source

<i>S</i>-HPABA, a marine fungal-derived bioactive compound, exhibits potent lipid-lowering efficacy and safety in modulating lipid dysregulation revealed by integrative lipidomics and molecular biology approaches. [PDF]

Front Nutr
Jia X, Yu M, Shen D, Fu H, Wang Y, Wang X, Huang J, Sun S, Yu Z, Chen Y, Zhao Y.   +10 more
europepmc   +1 more source

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

Cancer Science, Volume 117, Issue 11, Page 3007-3021, November 2026.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon, Min Young Lee, Jiwon Koh, Ki Yong Hong, Junji Fukuda, Sung Joon Kim, Yang‐Sook Chun   +6 more
wiley   +1 more source

Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties.

Cell
Prus G, Satpathy S, Weinert BT, Narita T, Choudhary C.   +4 more
europepmc   +1 more source

Cargo Stability of Extracellular Vesicles Derived From Non‐Diseased Sources: Effects of Storage and Handling Conditions

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi, Mina Mohammadinasr, Roza Motavalli, Narges Arianfar, Attabak Toofani‐Milani, Moein Shirzad, Vahid Hosseini, Masoud Darabi   +7 more
wiley   +1 more source

Quercetin Reduces Lipid Accumulation During Adipogenic Differentiation in Association with Stage-Dependent Mitochondrial-Redox and Metabolic Alterations Revealed by Time-Resolved ¹H NMR Metabolomics. [PDF]

Life (Basel)
Moe ATM, Htun KT, Pan J, Jaikumkao K, Intachai N, Lungkaphin A, Tapanya M, Pasanta D, Udomtanakunchai C, Tungjai M, Kaewjaeng S, Kim HJ, Kaewkhao J, Lai C, Kothan S.   +14 more
europepmc   +1 more source