Results 11 to 20 of about 19,839 (264)
photodegradation of 1 4 dihydropyridine antihypertensive drugs an updated review [PDF]
International Journal of Pharmacy and Pharmaceutical Sciences, 2018 1, 4-dihydropyridine calcium channels blockers (DHPs) are the most commonly used antihypertensive drugs. Unfortunately, these compounds have a significant degradability to light.
Claudia Spatari +3 more
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Molecules, 2012 Isothiazolopyridines, pyridothiazines and pyridothiazepines are important compounds that possess valuable biological activities. This paper reports on the synthesis of these compounds using both conventional chemical methods and modern microwave ...
Ayman M. S. Youssef +2 more
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Synthesis of 1, 4-Dihydropyridine Derivatives using FeCl3 as Catalyst under Solvent-free Condition
Oriental Journal Of Chemistry, 2013 Chemistry of dihydropyridines in 1882 with Ar thur Hansh reports the β-keto ester, aldehydes and ammonia can be combined to form 1, 4-dihydropyridine was developed. Because of the many benefits of 1, 4-dihydropridine is presented and now as vital medicines to treat angina, high blood pressure and allergies have been introduced.
ABDORRAHMAN KEYHANI, Farhad Hatamjafari
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Ethyl 4-oxo-1,4-dihydropyridine-3-carboxylate
IUCrData, 2021 The title compound, C8H9NO3, likely generated through hydrolysis and esterification of 3′-carboxy-3-methyl-(1,4′-bipyridin)-1-ium chloride by ethanol, which contained water, has a nearly planar conformation.
Jun Gao, Sihui Long
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Synthesis and assessment of the cytotoxic effect of some of 1,4-dihydropyridine derivatives which contain azole moiety [PDF]
Journal of the Serbian Chemical Society, 2021 A number of 1,4-dihydropyridine derivatives (9a–d, 10a–d and 11a–d) were designed and synthesized by the reaction of 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones to 2,6-dibromomethyl-3,5-diethoxycarbonyl-4-(3- -nitrophenyl)-1,4-dihydropyridine.
Ghoorbannejad Saeed +2 more
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Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity. [PDF]
Drug Dev ResABSTRACT Hexahydroquinoline (HHQ) is a widely recognized scaffold that has garnered considerable attention owing to its diverse pharmacological properties. The structure of HHQ includes a 1,4‐dihydropyridine (DHP) ring, which serves as the pharmacophore for the predominant class of drugs known as calcium channel blockers.
Koçak Aslan E +13 more
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10-Benzyl-9-(4-ethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione
Acta Crystallographica Section E, 2012 In the title compound, C32H37NO3, the central dihydropyridine ring adopts a nearly planar flattened-boat conformation, whereas both cyclohexenone rings adopt half-chair conformations.
V. Sughanya, N. Sureshbabu
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Data in Brief, 2020 In this data file the synthetic procedures for preparation of the original 4-pyridinium-1,4-dihydropyridines (4-Py-1,4-DHP) and their parent compounds – dialkyl 2,6-dimethyl-4-(3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylates were described. In total, 5
Klavs Pajuste +8 more
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Scientific Reports, 2021 The present work aims to study 6-amino-4-aryl-2-oxo-1-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives namely: 6-Amino-2-oxo-1,4-diphenyl-1,2-dihydropyridine-3,5-dicarbonitrile (PdC-H), 6-Amino-2-oxo-1-phenyl-4-(p-tolyl)-1,2-dihydropyridine-3,5 ...
Abd El-Aziz S. Fouda +4 more
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Hypertension in hemodialysis patients treated with atenolol or lisinopril: a randomized controlled trial [PDF]
, 2014 Background The purpose of this study was to determine among maintenance hemodialysis patients with echocardiographic left ventricular hypertrophy and hypertension whether in comparison with a β-blocker-based antihypertensive therapy, an angiotensin ...
Abraham, Terri N. +4 more
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