Results 21 to 30 of about 19,839 (264)
Research in Pharmaceutical Sciences, 2016 Changes in the substitutions at C-3 and C-5 positions of 4-(1-methyl-5-nitro-2-imidazolyl) dihydropyridine analogs of nifedipine have led to changes in potency of the compounds. The objective of the present study was to examine the hypotensive effects of
Sara Rowghani Haghighi Fard +2 more
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Кубанский научный медицинский вестник, 2022 Background. Over the past decades, scientific community is motivated on finding new anti-inflammatory agents with a safe and high-effective profile to manage pathology.Objectives. A study of the anti-inflammatory action of novel compounds, 1,4-dihydropyridine
E. Yu. Bibik +9 more
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Oxidative medicine and cellular longevity, 2016 Many 1, 4-dihydropyridines (DHPs) possess redox properties. In this review DHPs are surveyed as protectors against oxidative stress (OS) and related disorders, considering the DHPs as specific group of potential antioxidants with bioprotective capacities. They have several peculiarities related to antioxidant activity (AOA).
Žarković, Neven +1 more
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Design, Synthesis and Biological Evaluation of New 1, 4-Dihydropyridine (DHP) Derivatives as Selective Cyclooxygenase-2 Inhibitors. [PDF]
Iran J Pharm Res, 2015 Sabakhi I +5 more
europepmc +2 more sources
Simple Bronsted acid catalyzed C-H functionalization: efficient access to poly-substituted pyridines [PDF]
, 2016 An exceptionally simple and environmentally friendly methodology has been developed for directly functionalizing the benzylic C-H bond of the poly-substituted pyridines with aromatic imines.
Lai, SJ +6 more
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Rapid, Greener and One-pot Four Component Synthesis of 1, 4-Dihydropyridine Derivatives
Analytical Chemistry Letters, 2022 In this current research framework, an efficient greener synthesis has been developed for new pyridine derivatives using one-pot four-component reaction. We have synthesized a new series of 1,4-dihydropyridine derivatives in excellent yield via telescopic multicomponent reaction among the aldehyde, malononitrile, anilines and diethyl ...
Jadeja, Kiranba F., Joshi, Hitendra S.
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Water Extract of Dragon Fruit Peel Catalyzed Synthesis of Dihydropyridines By Hantzsch Condensation [PDF]
, 2021 Nowadays, natural substances are increasingly used in organic synthesis for their safety aspects towards the environment. That is why we identified a natural substance through which it promoted the organic reaction, and it could be sustainable and ...
Al-horaibi, Sultan Abduh +1 more
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Diethyl 2,6-dimethyl-4-(4-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylate
Acta Crystallographica Section E, 2010 In the title compound, C18H22N2O4, the dihedral angle between the two rings is 87.90 (6)°. The mean devation of the atoms in the dihydropyridine plane is 0.082 (3) Å. In the crystal, molecules are linked by
Yumei Li
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Data in Brief, 2022 In this data file the characterisation of nanoformulations obtained from calix[4]arene/1,4-dihydropyridine (1,4-DHP) compositions in the various component ratio in an aqueous medium was performed by dynamic light scattering (DLS) technique.
Martins Rucins +7 more
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Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators [PDF]
, 2004 A major problem in cancer treatment is the development of resistance to multiple chemotherapeutic agents in tumor cells. A major mechanism of this multidrug resistance (MDR) is overexpression of the MDR1 product P-glycoprotein, known to bind to and ...
Safa, Ahmad R.
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