Results 31 to 40 of about 90,592,261 (228)

Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity [PDF]

open access: yesScientific Reports, 2017
AbstractThe present study, we design and synthesize the novel dihydropyridine derivatives, i.e., 3 (a-e) and 5 (a-e) and evaluated, anticonvulsant activity. Initially due to the lacuna of LCC, we modeled the protein through modeller 9.15v and evaluated through servers.
Saddala, Madhu   +4 more
openaire   +5 more sources

Diethyl 4-(4-cyanophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesActa Crystallographica Section E, 2010
In the title compound, C20H22N2O4, the dihedral angle between the roughly planar dihydropyridine ring (r.m.s. deviation = 0.092 Å) and the benzene ring is 87.09 (6)°.
Peng Zhang, Weiqun Zhu
doaj   +1 more source

Data for characterisation of nanoformulations formed by cationic 1,4-dihydopyridine and calix[4]arene compositions

open access: yesData in Brief, 2022
In this data file the characterisation of nanoformulations obtained from calix[4]arene/1,4-dihydropyridine (1,4-DHP) compositions in the various component ratio in an aqueous medium was performed by dynamic light scattering (DLS) technique.
Martins Rucins   +7 more
doaj   +1 more source

Synthesis and antimicrobial activity of a new series of 1,4-dihydropyridine derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
A series of 1,4-dihydropyridine derivatives (1a–g) were prepared from Hantzsch syntheses. The compounds 1a–g were reacted with thiosemicarbazide to give the new series of compounds 2a–g. IR, 1H-NMR, 13C-NMR, mass spectral and elemental analysis confirmed
RADHAKRISHNAN SURENDRA KUMAR   +3 more
doaj  

Antibacterial and antileishmanial activity of 1,4-dihydropyridine derivatives [PDF]

open access: yes
We have synthesized twenty-three 1,4-dihydropyridine derivatives (1,4-DHPs) by using a microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their antibacterial activity against a representative panel of cariogenic bacteria and their ...
Thaís, Oliveira   +7 more
core   +2 more sources

Synthesis of 4-(2-Methylthiazol-4-yl)-Hexahydroquinoline and 1,4-Dihydropyrimidin Derivatives [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2011
A series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. Condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline
A. Shafiee
doaj  

Dihydropyridine-Based Multicomponent Reactions. Efficient Entry into New Tetrahydroquinoline Systems through Lewis Acid-Catalyzed Formal [4 + 2] Cycloadditions

open access: yes, 2016
The three-component reaction of dihydropyridines, aldehydes, and p-methylaniline efficiently forms highly substituted tetrahydroquinolines in a stereoselective manner through a Lewis acid-catalyzed formal [4 + 2] cycloaddition. InCl3 and Sc(OTf)3 are the
José Luis Díaz (2516782)   +3 more
core   +1 more source

Facile and rapid synthesis of piperidinium-6-amino-4-aryl-3, 5-dicyano-1,4-dihydropyridine-2-thiolate

open access: yes, 2019
A fast and convenient protocol for the synthesis of a new class of piperidin-1-ium 6-amino-4-aryl-3,5-dicyano-1,4-dihydropyridine-2-thiolate (piperidinium salt) derivatives is developed by the one-pot, three-component reactions of cyanothioacetamide ...
Milad Masoumi (5771438)   +2 more
core   +1 more source

Dimethyl 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesActa Crystallographica Section E, 2011
The title molecule, C17H19NO5, was prepared by a Hantzsch dihydropyridine synthesis from 4-hydroxybenzaldehyde, methyl acetoacetate and NH4HCO3.
Chun-Hua Zhang   +2 more
doaj   +1 more source

Rapid, Greener and One-pot Four Component Synthesis of 1, 4-Dihydropyridine Derivatives

open access: yesAnalytical Chemistry Letters, 2022
In this current research framework, an efficient greener synthesis has been developed for new pyridine derivatives using one-pot four-component reaction. We have synthesized a new series of 1,4-dihydropyridine derivatives in excellent yield via telescopic multicomponent reaction among the aldehyde, malononitrile, anilines and diethyl ...
Jadeja, Kiranba F., Joshi, Hitendra S.
openaire   +1 more source

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