Results 31 to 40 of about 9,315,415 (239)

Experimental, Molecular Docking and Molecular Dynamics Investigation on Newly Synthesized Diethyl 4-(Anthracen-9-yl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate

, 2022
The novel compound diethyl 4-(anthracen-9-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (DHPA) was synthesized via the Hantzsch method. The synthesized compound was studied through FT-IR, FT-Raman, UV-Vis and NMR studies were compared with ...
Velraj G (13218114), Karthick R (13218111), Karuppusamy A (13218117), Karthikeyan S (13218120)   +3 more
core   +1 more source

Tissue-specific expression of calcium channels [PDF]

, 1993
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit, Biel, Martin, Hullin, Roger, Hofmann, Franz   +3 more
core   +1 more source

1,4-Dihydropyridine Anions as Potent Single-Electron Photoreductants

, 2023
Organic anions offer a promising route for promoting difficult single-electron reductions, owing to their strongly reducing excit-ed states that can be accessed under visible light irradiation.
Spencer, Pitre, Mary, McKee, Prasadi, Gallage   +2 more
core   +1 more source

Data for the cytotoxicity, self-assembling properties and synthesis of 4-pyridinium-1,4-dihydropyridines

Data in Brief, 2020
In this data file the synthetic procedures for preparation of the original 4-pyridinium-1,4-dihydropyridines (4-Py-1,4-DHP) and their parent compounds – dialkyl 2,6-dimethyl-4-(3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylates were described. In total, 5
Klavs Pajuste, Martins Rucins, Ilona Domracheva, Arkadij Sobolev, Nadiia Pikun, Mara Plotniece, Gunars Duburs, Karlis Pajuste, Aiva Plotniece   +8 more
doaj   +1 more source

Experimental and computational chemical studies on the corrosion inhibitive properties of carbonitrile compounds for carbon steel in aqueous solutions

Scientific Reports, 2021
The present work aims to study 6-amino-4-aryl-2-oxo-1-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives namely: 6-Amino-2-oxo-1,4-diphenyl-1,2-dihydropyridine-3,5-dicarbonitrile (PdC-H), 6-Amino-2-oxo-1-phenyl-4-(p-tolyl)-1,2-dihydropyridine-3,5 ...
Abd El-Aziz S. Fouda, Abdelmonem H. El-Askalany, Ahmed F. S. Molouk, Niveen S. Elsheikh, Ashraf S. Abousalem   +4 more
doaj   +1 more source

Antihypertensive effects of new dihydropyridine derivatives on phenylephrine-raised blood pressure in rats

Research in Pharmaceutical Sciences, 2016
Changes in the substitutions at C-3 and C-5 positions of 4-(1-methyl-5-nitro-2-imidazolyl) dihydropyridine analogs of nifedipine have led to changes in potency of the compounds. The objective of the present study was to examine the hypotensive effects of
Sara Rowghani Haghighi Fard, Ramin Miri, Ali Akbar Nekooeian   +2 more
doaj   +1 more source

Study of novel 1,4-dihydropyridine derivatives as prospective anti-inflammatory remedies: a randomised controlled trial

Кубанский научный медицинский вестник, 2022
Background. Over the past decades, scientific community is motivated on finding new anti-inflammatory agents with a safe and high-effective profile to manage pathology.Objectives. A study of the anti-inflammatory action of novel compounds, 1,4-dihydropyridine
E. Yu. Bibik, D. S. Krivokolysko, G. A. Batishcheva, A. A. Samokish, Yu. S. Venidiktova, A. V. Myazina, A. A. Pankov, K. A. Frolov, V. V. Dotsenko, S. G. Krivokolysko   +9 more
doaj   +1 more source

Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity [PDF]

Scientific Reports, 2017
AbstractThe present study, we design and synthesize the novel dihydropyridine derivatives, i.e., 3 (a-e) and 5 (a-e) and evaluated, anticonvulsant activity. Initially due to the lacuna of LCC, we modeled the protein through modeller 9.15v and evaluated through servers.
Saddala, Madhu, Kandimalla, Ramesh, Adi, Pradeepkiran, Bhashyam, Sainath, Asupatri, Usha   +4 more
openaire   +5 more sources

Data for characterisation of nanoformulations formed by cationic 1,4-dihydopyridine and calix[4]arene compositions

Data in Brief, 2022
In this data file the characterisation of nanoformulations obtained from calix[4]arene/1,4-dihydropyridine (1,4-DHP) compositions in the various component ratio in an aqueous medium was performed by dynamic light scattering (DLS) technique.
Martins Rucins, Roman Rodik, Aiva Plotniece, Nadiia Pikun, Mara Plotniece, Arkadij Sobolev, Vitaly Kalchenko, Karlis Pajuste   +7 more
doaj   +1 more source

Diethyl 4-(4-cyanophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Acta Crystallographica Section E, 2010
In the title compound, C20H22N2O4, the dihedral angle between the roughly planar dihydropyridine ring (r.m.s. deviation = 0.092 Å) and the benzene ring is 87.09 (6)°.
Peng Zhang, Weiqun Zhu
doaj   +1 more source