Results 41 to 50 of about 19,839 (264)
First organocatalytic asymmetric synthesis of 1-Benzamido-1, 4-Dihydropyridine Derivatives [PDF]
Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1, 4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles in the presence of ß-isocupreidine catalyst are reported. The
Auria-Luna, F. +2 more
core +1 more source
Cytotoxic effect of some 1, 4-dihydropyridine derivatives containing nitroimidazole moiety.
The 1,4-dihydropyridine (DHP) derivatives are a known class of calcium channel blockers. Some derivatives of DHP showed significant cytotoxicity. It was shown that this effect may not be the result of interaction with Ca(2+) channels. In this study, we performed an investigation about the intrinsic cytotoxicity of some derivatives of DHP containing ...
Miri, Ramin +6 more
openaire +2 more sources
Dimethyl 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
The title molecule, C17H19NO5, was prepared by a Hantzsch dihydropyridine synthesis from 4-hydroxybenzaldehyde, methyl acetoacetate and NH4HCO3.
Chun-Hua Zhang +2 more
doaj +1 more source
One-Pot Synthesis of 1, 4-Dihydropyridines in PEG Under Catalyst-Free Conditions [PDF]
A simple, inexpensive, and efficient one-pot synthesis of 1,4-dihydropyridine via Hantzsch reaction was achieved in good to excellent yields under catalyst free conditions by using PEG400 as solvent. In this reaction, PEG-400 was used as the solvent, which has such advantages: absolutely nontoxic, inexpensive, thermally stable, recoverable and easy to ...
Shuwei Zhang +5 more
openaire +1 more source
This data file describes the synthetic protocol for preparation of the original 2,6-di(bromomethyl)-3,5-bis(alkoxycarbonyl)-4-aryl-1,4-dihydropyridines. In total, 6 unpublished compounds were obtained and characterised.
Martins Rucins +6 more
doaj +1 more source
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger +9 more
wiley +1 more source
Selective Mono Bromination of 1,4-Dihydropyridines [PDF]
2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-
Yousef Rastgar Mirzaei +1 more
doaj
4-Oxo-N-phenyl-1,4-dihydropyridine-3-carboxamide
The title compound, C12H10N2O2, shows a nearly planar conformation. The crystal structure is sustained by hydrogen bonds between the NH and the carbonyl O function of the 4-oxo-1,4-dihydropyridine ring of the molecules, forming infinite chains along the ...
Xi Shu, Sihui Long
doaj +1 more source
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang +6 more
wiley +1 more source
اندازهگيری مبوديپين در مايعات بيولوژيک با روش HPLC و کاربرد اين دارو در مطالعه فارماکوکينتيک در موش صحرايی An HPLC Method for Determination of Mebudipine in Biological Fluids in Rats and its Application in Pharmacokinetic Study [PDF]
زمينه و هدف: داروی مبوديپين يک داروی کلسيم آنتاگونيست بوده با ساختمان 4/1 دیهيدروپيريدين میباشد که در درمان فشار خون میتواند موثر باشد. در اين مطالعه يک روش HPLC برای اندازهگيری اين ماده در سرم ابداع شده که برای مطالعه فارماکوکنيتک اين دارو پس از ...
بهلولی, شهاب +3 more
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