Results 41 to 50 of about 9,315,415 (239)

Rapid, Greener and One-pot Four Component Synthesis of 1, 4-Dihydropyridine Derivatives

Analytical Chemistry Letters, 2022
In this current research framework, an efficient greener synthesis has been developed for new pyridine derivatives using one-pot four-component reaction. We have synthesized a new series of 1,4-dihydropyridine derivatives in excellent yield via telescopic multicomponent reaction among the aldehyde, malononitrile, anilines and diethyl ...
Jadeja, Kiranba F., Joshi, Hitendra S.
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Synthesis and antimicrobial activity of a new series of 1,4-dihydropyridine derivatives [PDF]

Journal of the Serbian Chemical Society, 2011
A series of 1,4-dihydropyridine derivatives (1a–g) were prepared from Hantzsch syntheses. The compounds 1a–g were reacted with thiosemicarbazide to give the new series of compounds 2a–g. IR, 1H-NMR, 13C-NMR, mass spectral and elemental analysis confirmed
RADHAKRISHNAN SURENDRA KUMAR, AKBAR IDHAYADHULLA, ABDUL JAMAL ABDUL NASSER, JOSEPH SELVIN   +3 more
doaj  

Facile and rapid synthesis of piperidinium-6-amino-4-aryl-3, 5-dicyano-1,4-dihydropyridine-2-thiolate

, 2019
A fast and convenient protocol for the synthesis of a new class of piperidin-1-ium 6-amino-4-aryl-3,5-dicyano-1,4-dihydropyridine-2-thiolate (piperidinium salt) derivatives is developed by the one-pot, three-component reactions of cyanothioacetamide ...
Milad Masoumi (5771438), Mohammad Bayat (3335955), Fahimeh Sadat Hosseini (4753608)   +2 more
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Alterations in dihydropyridine receptors in dystrophin-deficient cardiac muscle [PDF]

, 2006
The deficiency of dystrophin, a critical membrane stabilizing protein, in the mdx mouse causes an elevation in intracellular calcium in myocytes. One mechanism that could elicit increases in intracellular calcium is enhanced influx via the L-type calcium
Lu, Sai, Watson, M, Woolf, Peter James, Hoey, AJ, Cornford-Nairn, R, Holroyd, SM, Hoey, Andrew, Woolf, PJ, Cornford-Nairn, Renee, Hoey, Andrew J., Xiao, Xiao-Hui, Woolf, Peter J., Xiao, XH, Holroyd, Sean M., Watson, Michael, Cornford-Nairn, Renee A., Brown, Lindsay, Holroyd, Sean, Brown, L   +18 more
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Synthesis of 4-(2-Methylthiazol-4-yl)-Hexahydroquinoline and 1,4-Dihydropyrimidin Derivatives [PDF]

Journal of Sciences, Islamic Republic of Iran, 2011
A series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. Condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline
A. Shafiee
doaj  

Dihydropyridine-Based Multicomponent Reactions. Efficient Entry into New Tetrahydroquinoline Systems through Lewis Acid-Catalyzed Formal [4 + 2] Cycloadditions

, 2016
The three-component reaction of dihydropyridines, aldehydes, and p-methylaniline efficiently forms highly substituted tetrahydroquinolines in a stereoselective manner through a Lewis acid-catalyzed formal [4 + 2] cycloaddition. InCl3 and Sc(OTf)3 are the
José Luis Díaz (2516782), Inés Carranco (3027048), Rodolfo Lavilla (1892905), M. Carmen Bernabeu (3066654)   +3 more
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Cytotoxic effect of some 1, 4-dihydropyridine derivatives containing nitroimidazole moiety.

Iranian journal of pharmaceutical research : IJPR, 2011
The 1,4-dihydropyridine (DHP) derivatives are a known class of calcium channel blockers. Some derivatives of DHP showed significant cytotoxicity. It was shown that this effect may not be the result of interaction with Ca(2+) channels. In this study, we performed an investigation about the intrinsic cytotoxicity of some derivatives of DHP containing ...
Miri, Ramin, Javidnia, Katayoun, AmirGhofran, Zahra, Salimi, Seyyed Hossein, Sabetghadam, Zahra, Meili, Savis, Mehdipour, Ahmad Reza   +6 more
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Dimethyl 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Acta Crystallographica Section E, 2011
The title molecule, C17H19NO5, was prepared by a Hantzsch dihydropyridine synthesis from 4-hydroxybenzaldehyde, methyl acetoacetate and NH4HCO3.
Chun-Hua Zhang, Jing-Min Zhao, Bao-Guo Chen   +2 more
doaj   +1 more source

1, 4-Dihydropyridine Derivatives : Dihydronicotinamide Analogues—Model Compounds Targeting Oxidative Stress1, 4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues—Model Compounds Targeting Oxidative Stress

Oxidative medicine and cellular longevity, 2016
Many 1, 4-dihydropyridines (DHPs) possess redox properties. In this review DHPs are surveyed as protectors against oxidative stress (OS) and related disorders, considering the DHPs as specific group of potential antioxidants with bioprotective capacities. They have several peculiarities related to antioxidant activity (AOA).
Žarković, Neven, Gall Trošelj, Koraljka   +1 more
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A Systematic Review on 1, 4-Dihydropyridines and its Analogues: An Elite Scaffold

Biointerface Research in Applied Chemistry, 2021
1,4-Dihydropyridines are a group of pyridine-based molecules possessing a magnificent set of biological and therapeutic potentials. Belonging to the class of calcium channel blockers, they are known to be effective in the conditions, angina, hypertension, myocardial infarction and show vasodilatory and cardiac depressant effects.
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