Results 41 to 50 of about 90,592,261 (228)
Synthesis and Utility of Dihydropyridine Boronic Esters [PDF]
, 2016 When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine ...
Santanu Panda +9 more
core +1 more source
Selective Mono Bromination of 1,4-Dihydropyridines [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1997 2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-
Yousef Rastgar Mirzaei +1 more
doaj
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
A flavone 1,4-dihydropyridine calcium antagonist
, 1999 In the title compound, diethyl 2,6-dimethyl-4-(2-phenyl-4-oxo-4H-1-benzopyran-6-yl)-1,4-dihydropyridine-3,5-dicarboxylate, C28H27NO6, the 1,4-dihydropyridine ring exhibits a boat conformation. The benzopyran moiety of the flavone is nearly planar, and is
AYHAN, GÖKÇE +3 more
core +1 more source
, 2022 The novel compound diethyl 4-(anthracen-9-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (DHPA) was synthesized via the Hantzsch method. The synthesized compound was studied through FT-IR, FT-Raman, UV-Vis and NMR studies were compared with ...
Velraj G (13218114) +3 more
core +1 more source
Data in Brief, 2020 This data file describes the synthetic protocol for preparation of the original 2,6-di(bromomethyl)-3,5-bis(alkoxycarbonyl)-4-aryl-1,4-dihydropyridines. In total, 6 unpublished compounds were obtained and characterised.
Martins Rucins +6 more
doaj +1 more source
Diversity-Oriented Synthesis of 1‑Substituted 4‑Aryl-6-oxo-1,6-dihydropyridine-3-carboxamides.
, 2016 A simple five-step diversity-oriented synthesis of 1-substituted 4-aryl-6-oxo-1,6-dihydropyridine-3-carboxamides was developed. Treatment of dimethyl 2-((dimethylamino)methylidene)-3-oxopentanedioate with twenty primary amines gave 1-substituted methyl ...
Jurij Svete (1447174) +6 more
core +1 more source
Effective fabrication of poly(anilin-formaldehyde)-supported hybrid nanomaterial and catalytic synthesis of dihydropyridines [PDF]
Nanochemistry Research, 2019 In this study, Fe3O4@SiO2-PAF-SO3H nanocomposite was successfully fabricated by immobilization of sulfonic acid groups on the surface of poly(anilin-formaldehyde)-supported on magnetic Fe3O4@SiO2 nanoparticles through layer-by-layer assembly.
Mohammad Ali Bodaghifard +2 more
doaj +1 more source
A Systematic Review on 1, 4-Dihydropyridines and its Analogues: An Elite Scaffold
Biointerface Research in Applied Chemistry, 2021 1,4-Dihydropyridines are a group of pyridine-based molecules possessing a magnificent set of biological and therapeutic potentials. Belonging to the class of calcium channel blockers, they are known to be effective in the conditions, angina, hypertension, myocardial infarction and show vasodilatory and cardiac depressant effects.
openaire +1 more source
, 2016 Some novel dihydropyridine derivatives, viz., 4-(4-hydroxy-3-methoxyphenyl)-6-(2-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile, 4-(4-hydroxy-3-methoxyphenyl)-6-(4-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile, 6-(4-chlorophenyl)-4-(4 ...
Rahul M. Talaviya (2544049) +1 more
core +1 more source