Results 111 to 120 of about 2,273 (170)

Alkaptonuria and Cervical Disc Herniation: Case Report. [PDF]

open access: yesInt J Spine Surg
Sampaio Júnior FAU   +11 more
europepmc   +1 more source

Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria. [PDF]

open access: yesHum Mol Genet
Rutland DA   +8 more
europepmc   +1 more source

High-yield production of hydroxytyrosol through metabolic engineering of <i>Yarrowia lipolytica</i>. [PDF]

open access: yesSynth Syst Biotechnol
Chen B   +6 more
europepmc   +1 more source

Therapeutic adenine base editor with minimized off-target effects. [PDF]

open access: yesProtein Cell
Sun Y   +6 more
europepmc   +1 more source

Cardiovascular involvement in Alcaptonuria: a case report on ochronotic aortic valve. [PDF]

open access: yesJ Cardiothorac Surg
Yusifli A   +5 more
europepmc   +1 more source

Shikimate crosstalk enables record-level homogentisic acid production in <i>Yarrowia lipolytica</i>. [PDF]

open access: yesSynth Syst Biotechnol
Xu C   +6 more
europepmc   +1 more source

4-Hydroxyphenylpyruvate dioxygenase

Archives of Biochemistry and Biophysics, 2005
4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an Fe(II)-dependent, non-heme oxygenase that catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. This reaction involves decarboxylation, substituent migration and aromatic oxygenation in a single catalytic cycle.
Graham Moran
exaly   +3 more sources

On 4-hydroxyphenylpyruvate dioxygenase of adult frog liver

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1982
1. It has been reported that 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) activity in the liver from Rana esculenta is present only after autolysis of trypsin digestion, which releases a heat-and acid-stable inhibitor of low molecular mass. 2. Attempts to demonstrate similar effects with the liver enzyme from adult Rana pipiens were unsuccessful.
S, Lindstedt, B, Odelhög, M, Rundgren
openaire   +2 more sources

Novel Pyrazole Amides as Potential 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

Journal of Agricultural and Food Chemistry, 2022
4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an important target for the development of new herbicides. HPPD inhibitors can hinder photosynthesis and induce weed death with bleaching symptoms. To explore the novel skeleton of HPPD inhibitors, a series of novel pyrazole amide derivatives were synthesized and evaluated for their inhibitory effects on ...
Huanan Zeng   +5 more
openaire   +2 more sources

Human 4‐hydroxyphenylpyruvate dioxygenase

European Journal of Biochemistry, 1993
We report the primary structure of 4‐hydroxyphenylpyruvate dioxygenase [4‐hydroxyphenylpyruvate: oxygen oxidoreductase (hydroxylating, decarboxylating)]. The work is based on the isolation of cDNA clones from human liver λgt11 libraries. Several overlapping clones covering the coding sequence were characterized.
U, Rüetschi   +5 more
openaire   +2 more sources

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