Results 91 to 100 of about 12,760,006 (203)

4-Hydroxyphenylpyruvate Dioxygenase (HPPD)-Inhibiting Herbicides: Past, Present, and Future [PDF]

, 2022
The 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicides are primarily used for weed control in corn, barley, oat, rice, sorghum, sugarcane, and wheat production fields in the United States. The objectives of this review were to summarize (1)
Norsworthy, Jason K., Jhala, Amit J., Burton, Paul M., Dale, Richard P., Dayan, Franck E., Yadav, Ramawatar, Jha, Prashant, Kumar, Vipan, Jugulam5, Mithila, Williams, Martin M., II, Hausman, Nicholas E.   +10 more
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Human 4-hydroxyphenylpyruvate dioxygenase. Primary structure and chromosomal localization of the gene

, 1993
We report the primary structure of 4-hydroxyphenylpyruvate dioxygenase [4-hydroxyphenyl-pyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)]. The work is based on the isolation of cDNA clones from human liver lambda gt11 libraries.
Lindstedt, Sven,, Rüetschi, Ulla,, Stenman, Göran,, Dellsén, A,, Sahlin, Pelle,, Rymo, Lars,   +5 more
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Hawkinsinuria clinical practice guidelines: a Mexican case report and literature review

Journal of International Medical Research, 2020
Hawkinsinuria is an autosomal dominant disorder of tyrosine metabolism. Mutations in the 4-hydroxyphenylpyruvate dioxygenase gene ( HPD ) result in an altered HPD enzyme, causing hawkinsin and tyrosine accumulation.
Héctor Cruz-Camino, Diana Laura Vazquez-Cantu, Alexandra Vanessa Zea-Rey, Jaime López-Valdez, Jorge Jiménez-Lozano, René Gómez-Gutiérrez, Consuelo Cantú-Reyna   +6 more
doaj   +1 more source

Novel bacterial bioassay for a high-throughput screening of 4-hydroxyphenylpyruvate dioxygenase inhibitors

, 2014
International audiencePlant 4-hydroxyphenylpyruvate dioxygenase (HPPD) is the molecular target of a range of synthetic β-triketone herbicides that are currently used commercially.
Bertrand, Cédric, Rocaboy-Faquet, Emilie, Romdhane, Sana, Noguer, Thierry, Barthelmebs, Lise, Dayan, Franck Emmanuel   +5 more
core   +1 more source

The use of medical foods and of an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (NTBC) to improve rickets in tyrosinaemia type 1

, 2001
The use of special foods and an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (NTBC) are discussed as crucial keys to improve rickets in a child with tyrosinaemia type
Rigante, D
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Mutations of Asn321 and Glu322 Improve Resistance of 4‑Hydroxyphenylpyruvate Dioxygenase SpHPPDm to Topramezone

, 2022
As a highly efficient 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicide, topramezone is an ideal target for herbicide-resistant genetic engineering. In this study, two mutants, K-19 (N321Y) and K-63 (Q166R/E322V), with topramezone resistance
Bin Liu (5899), Peng Lei (216846), Le Chen (1446445), Jian He (35118), Jianchun Zhu (10202656), Qin He (499660), Haiyan Wang (25821)   +6 more
core   +1 more source

The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake

Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide.
Zachary Thomas Stavrou-Dowd, George Parsons, Clair Rose, Faye Brown, Rosemary Susan Lees, Álvaro Acosta-Serrano, Lee Rafuse Haines   +6 more
doaj   +1 more source

The formation of homogentisate in the biosynthesis of tocopherol and plastoquinone in spinach chloroplasts [PDF]

, 1982
Homogentisate is the precursor in the biosynthesis of -tocopherol and plastoquinone-9 in chloroplasts. It is formed of 4-hydroxyphenylpyruvate of the shikimate pathway by the 4-hydroxyphenylpyruvate dioxygenase.
Soll, Jürgen, Jürgen Soll, Schultz, Gernot, Fiedler, Erich, Erich Fiedler, Gernot Schultz   +5 more
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HPDL Variant Type Correlates With Clinical Disease Onset and Severity

Annals of Clinical and Translational Neurology
Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic ...
Eun Hye Lee, Olivia Kim‐Mcmanus, Jennifer H. Yang, Richard Haas, Maha S. Zaki, Ghada M. H. Abdel‐Salam, Yuji Nakamura, Mohamed S. Abdel‐Hamind, Darius Ebrahimi‐Fakhari, Julian E. Alecu, Nicola Brunetti‐Pierri, Varunvenkat M. Srinivasan, Vykuntaraju K. Gowda, Stephanie Gross, Yasemin Alanay, Paria Najarzadeh Totbati, Manya Yadavilli, Liana Friedman, Naomi Meave Ojeda, Joseph G. Gleeson   +19 more
doaj   +1 more source

Novel Pyrazole Amides as Potential 4‑Hydroxyphenylpyruvate Dioxygenase Inhibitors

4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an important target for the development of new herbicides. HPPD inhibitors can hinder photosynthesis and induce weed death with bleaching symptoms.
Xiuhai Gan (3948902), Zhengxing Wang (8180718), Wei Zhang (405), Gang Feng (130630), Huanan Zeng (9671214), Wang Geng (12860179)   +5 more
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