Results 91 to 100 of about 2,253 (135)

Identification of a novel 4-hydroxyphenylpyruvate dioxygenase from the soil metagenome

Biochemical and Biophysical Research Communications, 2008
4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a Fe(II)-dependent, non-heme oxygenase that converts 4-hydroxyphenylpyruvate to homogentisate. Essential cofactors, such as plastoquinone and tocopherol, are produced by HPPD-dependent anabolic pathways in plants.
Chang-Muk, Lee, Yun-Soo, Yeo, Jung-Han, Lee, Soo-Jin, Kim, Jung-Bong, Kim, Nam Soo, Han, Bon-Sung, Koo, Sang-Hong, Yoon   +7 more
openaire   +2 more sources

Improving the herbicide resistance of 4-hydroxyphenylpyruvate dioxygenase SpHPPD by directed evolution

Enzyme and Microbial Technology, 2022
Topramezone, a highly efficient 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor herbicide, is an ideal target for herbicide-resistant genetic engineering. However, there is still a lack of HPPD gene that is highly resistant to topramezone. In previous studies, we obtained a topramezone-resistant HPPD (SpHPPDm) gene from Sphingobium sp.
Haiyan, Wang, Bin, Liu, Peng, Lei, Jianchun, Zhu, Le, Chen, Qin, He, Jian, He   +6 more
openaire   +2 more sources

Cypyrafluone, a 4-Hydroxyphenylpyruvate Dioxygenase Inhibitor to Control Weed in Wheat Fields

Journal of Agricultural and Food Chemistry, 2023
As a bleaching herbicide, cypyrafluone was applied postemergence in wheat fields for annual weed control; especially, this herbicide possesses high efficacy against cool-season grass weed species such as Alopecurus aequalis and Alopecurus japonicus.
Lei Lian, Hengzhi Wang, Fengwen Zhang, Weitang Liu, Xingtao Lu, Tao Jin, Jinxin Wang, Xiuhai Gan, Baoan Song   +8 more
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Design and Syntheses of Proherbicides Targeting 4-Hydroxyphenylpyruvate Dioxygenase

Journal of Agricultural and Food Chemistry
4-Hydroxyphenylpyruvate dioxygenase (HPPD, EC 1.13.11.27) is regarded as a crucial target in the domain of herbicide discovery. Herein, we adopted the proherbicides concept, based on the initially discovered lead compound II-aa. Our group has designed four derivatives by incorporating alkyl, carbonyl ester, sulfonyl ester, and phosphate ester fragments.
Bo He, Li-jun Chen, Yi-xuan Fu, Tian-zhu Zhang, Feng-xu Wu, Jin Dong, Liang-Kun Yu, Xian-Quan Wang, Hong-Yan Lin, Guang-Fu Yang   +9 more
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4-Hydroxyphenylpyruvate Dioxygenase Inhibitors: From Chemical Biology to Agrochemicals

Journal of Agricultural and Food Chemistry, 2017
The development of new herbicides is receiving considerable attention to control weed biotypes resistant to current herbicides. Consequently, new enzymes are always desired as targets for herbicide discovery. 4-Hydroxyphenylpyruvate dioxygenase (HPPD, EC 1.13.11.27) is an enzyme engaged in photosynthetic activity and catalyzes the transformation of 4 ...
Ferdinand Ndikuryayo, Behrooz Moosavi, Wen-Chao Yang, Guang-Fu Yang   +3 more
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Mechanism and Mechanism-Based Inactivation of 4-Hydroxyphenylpyruvate Dioxygenase

Bioorganic Chemistry, 1994
Abstract Six substrate analogs of 4-hydroxyphenylpyruvate, specifically pentafluorophenylpyruvate, 4-hydroxytetrafluorophenylpyruvate,2-thienylpyruvate, 3-thienylpyruvate, thiophenol oxalate, and p -thiocresoloxalate were synthesized and their interactions with porcine liver 4-hydroxyphenylpyruvate dioxygenase investigated.
B.J.R. Forbes, G.A. Gordon
openaire   +1 more source

Purification and Characterization of 4-Hydroxyphenylpyruvate Dioxygenase from Maize

Pesticide Science, 1996
The proposed target enzyme for benzoylcyclohexanedione herbicides, 4-hydroxyphenylpyruvate dioxygenase (HPPD) was purified from etiolated maize seedlings with a purification factor of 105. Enzyme activity was measured by detection of carbon dioxide formed from radiolabelled substrate. The enzyme has a pH optimum of 7.3 and an apparent molecular mass of
Istvan Cs. Barta, Peter Böger
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Advances in Understanding the Toxicity of 4-Hydroxyphenylpyruvate Dioxygenase-Inhibiting Herbicides

Journal of Agricultural and Food Chemistry
4-Hydroxyphenylpyruvate dioxygenase inhibiting herbicides (HIHs) represent a recent class (HRAC group 27) of herbicides that offer many advantages, such as broad-spectrum activity, crop selectivity, and low resistance rates. However, emerging studies have highlighted the potential toxicity of HIHs in the environment.
Ferdinand Ndikuryayo, Xue-Yan Gong, Wen-Chao Yang   +2 more
openaire   +2 more sources

4-Hydroxyphenylpyruvate Dioxygenase Inhibitors: From Molecular Design to Synthesis

Journal of Agricultural and Food Chemistry
Weed resistance is a critical issue in crop production. Among the known herbicides, 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors are crucial for addressing weed resistance. HPPD inhibitors constitute a pivotal aspect of contemporary crop protection strategies.
Tengfei Ma, Shuang Gao, Li-Xia Zhao, Fei Ye, Ying Fu   +4 more
openaire   +2 more sources

A Protocol for Activated Bioorthogonal Fluorescence Labeling and Imaging of 4-Hydroxyphenylpyruvate Dioxygenase in Plants

Angewandte Chemie - International Edition, 2023
Sheng Hua Liu, Guang-Fu Yang, Jun Yin
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