Results 81 to 90 of about 12,760,006 (203)
Vitiligo, alkaptonuria, and nitisinone—A report of three families and review of the literature
JIMD Reports, 2021 Four patients, from three families, with alkaptonuria receiving 4‐hydroxyphenylpyruvate dioxygenase‐inhibiting nitisinone therapy, which lowers homogentisic acid and increases tyrosine, developed vitiligo.
Lakshminarayan Ranganath +5 more
doaj +1 more source
Pest Management Science, Volume 82, Issue 2, Page 1842-1852, February 2026.Herbicides elicit a spectrum of responses in Nitrospirillum amazonense, ranging from the stimulation of metabolic functions (biological nitrogen fixation, IAA production) to significant growth inhibition and acute toxicity. Abstract BACKGROUND Herbicides can exert significant toxicity on nontarget organisms, including plant growth‐promoting bacteria ...
Luana Carolina Gomes Jonck +3 more
wiley +1 more source
Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione [PDF]
, 2009 Triketone herbicides are inhibitors of 4-hydroxyphenylpyruvate dioxygenase (HPPD), a key enzyme of the tyrosine transformation pathway, common for plants and animals.
Molchanov, Sergey, Gryff-Keller, Adam
core
The phytotoxic lichen metabolite, usnic acid, is a potent inhibitor of plant p-hydroxyphenylpyruvate dioxygenase [PDF]
, 2000 The lichen secondary metabolite usnic acid exists as a (−) and a (+) enantiomer, indicating a α or β projection of the methyl group at position 9b, respectively.
Nanayakkara, N.P.Dhammika +7 more
core +1 more source
A Case of Tyrosinemia Type III with Status Epilepticus and Mental Retardation
Advanced Biomedical Research, 2018 Tyrosinemia type III is an autosomal recessive disorder caused by the deficiency of 4- hydroxyphenylpyruvate dioxygenase (4-HPPD). It is characterized by elevated levels of blood tyrosine and massive excretion of its derivatives into the urine.
Reza Najafi +2 more
doaj +1 more source
JIMD Reports, Volume 67, Issue 1, January 2026.ABSTRACT Hereditary tyrosinemia type I (HT‐1) is a rare metabolic disorder treated by NTBC, requiring careful therapeutic and nutritional monitoring. While follow‐up traditionally relies on urinary succinylacetone, plasma NTBC and plasma amino acids, dried blood spot (DBS) methods have introduced alternative monitoring options.
Anne‐Sophie Adam +7 more
wiley +1 more source
EFSA Journal, Volume 24, Issue 1, January 2026.Abstract Genetically modified soybean GMB151 × DAS‐44406‐6 was developed by crossing to combine two single events: GMB151 and DAS‐44406‐6. The two‐event stack soybean expresses the Cry14Ab‐1, HPPD‐4, PAT, AAD‐12 and 2mEPSPS proteins to confer herbicide tolerance and resistance to plant parasitic nematodes.
EFSA Panel on Genetically Modified Organisms (GMO) +28 more
wiley +1 more source
, 2002 A comparative molecular field analysis (CoMFA) of alkanoic acid 3-oxo-cyclohex-1-enyl ester and 2-acylcyclohexane-1,3-dione derivatives of 4-hydroxyphenylpyruvate dioxygenase inhibitors has been performed to determine the factors required for the ...
Yang, D-Y. +4 more
core +1 more source
The Incidence of Transient Neonatal Tyrosinemia Within a Mexican Population
Journal of Inborn Errors of Metabolism and Screening, 2017 Transient neonatal tyrosinemia (TNT) is a form of hypertyrosinemia produced by the immaturity of 4-hydroxyphenylpyruvate dioxygenase (4-HPPD), a high intake of phenylalanine and tyrosine, and a relative ascorbic acid deficiency.
Alexandra V. Zea-Rey MD +5 more
doaj +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT The essential oil of Medicago marina was subjected to analysis at vegetative and reproductive stages of development, with a particular emphasis on its chemical composition, α‐amylase inhibition, and allelopathic activities. The results of the gas chromatography and molecular docking studies demonstrated alterations in oil yield and composition
Marwa Melliti +9 more
wiley +1 more source