Results 21 to 30 of about 2,273 (170)

Pyomelanin produced by Streptomyces sp. ZL-24 and its protective effects against SH-SY5Y cells injury induced by hydrogen peroxide

Scientific Reports, 2021
A soluble melanin pigment produced by Streptomyces sp. ZL-24 was purified and named StrSM. The elemental analysis of StrSM showed it consists of carbon, hydrogen, and oxygen.
Yumei Li, Zhengmao Ye, Peng Lu, Lingchao Lu   +3 more
doaj   +1 more source

The mutation spectrum and ethnic distribution of non-hepatorenal tyrosinemia (types II, III)

Orphanet Journal of Rare Diseases, 2022
Background Different types of non-hepatorenal tyrosinemia are among the rare forms of tyrosinemia. Tyrosinemia type II and III are autosomal recessive disorders caused by pathogenic variants in the tyrosine aminotransferase (TAT), and 4-hydroxyphenyl ...
Zahra Beyzaei, Sara Nabavizadeh, Sara Karimzadeh, Bita Geramizadeh   +3 more
doaj   +1 more source

Bioinformatics analysis of 4Hppd gene in Sporothrix schenckii

Pifu-xingbing zhenliaoxue zazhi, 2020
Objective: To predict biological characterisics of 4-HppD, encoded by 4Hppd in Sporothrix schenckii. Methods: Mutiple bioinformatics online tools were used to analyse the sequence.
Xiao-yan WU, Jing ZHANG, Jia-min HUANG, Yao SUN, Xiao-wen HUANG, Wen-chao GAO, Rong WU, San-mei CHEN, Huai-qiu HUANG   +8 more
doaj   +1 more source

Discovery of tetrazolium nicotinamide derivatives as novel 4-Hydroxyphenylpyruvate dioxygenase inhibiting-based herbicides

Advanced Agrochem, 2023
4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD) is currently one of the popular targets of herbicide research, and herbicides targeting it have shown promising results in treating resistant weeds.
Li-Jun Chen, Guang-Yi Huang, Jin Dong, Zhuo-Mei Cai, Bao-Qing Ye, Qiong Chen, Hong-Yan Lin   +6 more
doaj   +1 more source

Characterization of 4‐hydroxyphenylpyruvate dioxygenase [PDF]

European Journal of Biochemistry, 1992
The primary structure of Pseudomonas 4‐hydroxyphenylpyruvate dioxygenase was determined. Sequence degradation of the intact protein and of peptides from three different digests of the carboxymethylated protein established a 357‐residue polypeptide chain with a free α‐amino group.
U, Rüetschi, B, Odelhög, S, Lindstedt, J, Barros-Söderling, B, Persson, H, Jörnvall   +5 more
openaire   +3 more sources

Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2‐dioxygenase deficiency in the liver is responsible for homogentisic acid‐derived ochronotic pigmentation

JIMD Reports, 2021
Alkaptonuria (AKU) is caused by homogentisate 1,2‐dioxygenase (HGD) deficiency. This study aimed to determine if HGD and other enzymes related to tyrosine metabolism are associated with the location of ochronotic pigment. Liver, kidney, skin, bone, brain,
Peter J. M. Wilson, Lakshminarayan R. Ranganath, George Bou‐Gharios, James A. Gallagher, Juliette H. Hughes   +4 more
doaj   +1 more source

Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress

Advanced Agrochem, 2022
The upregulation of 4-hydroxyphenylpyruvate dioxygenase (HPPD) can protect plants from adverse abiotic stress. Therefore, studying the changes of HPPD under abiotic stress is extremely valuable.
Xiaoyan Zeng, Yurou Huang, Jing Dong, Xiaoxie Ma, Jia-Xu Nan, Weijie Chen, Hong-Yan Lin, Wen-Chao Yang, Xiaogang Liu, Jun Yin, Guang-Fu Yang   +10 more
doaj   +1 more source

Synthesis and herbicidal activities of aryloxyacetic acid derivatives as HPPD inhibitors

Beilstein Journal of Organic Chemistry, 2020
A series of aryloxyacetic acid derivatives were designed and synthesized as 4-hydoxyphenylpyruvate dioxygenase (HPPD) inhibitors. Preliminary bioassay results reveal that these derivatives are promising Arabidopsis thaliana HPPD (AtHPPD) inhibitors, in ...
Man-Man Wang, Hao Huang, Lei Shu, Jian-Min Liu, Jian-Qiu Zhang, Yi-Le Yan, Da-Yong Zhang   +6 more
doaj   +1 more source

Vibrio splendidus virulence to Apostichopus japonicus is mediated by hppD through glutamate metabolism and flagellum assembly

Virulence, 2022
Vibrio splendidus is the main opportunistic pathogen that causes skin ulcer syndrome in Apostichopus japonicus. hppDIn the present study, mutant V. splendidus with an in-frame deletion of hppDV.s. (MTVs) was constructed.
Weikang Liang, Weiwei Zhang, Chenghua Li
doaj   +1 more source

Human 4-Hydroxyphenylpyruvate Dioxygenase Gene (HPD)

Genomics, 1997
Overlapping DNA fragments spanning approximately 21 kb of genomic DNA and encompassing the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) have been cloned by screening a human leukocyte genomic library and by PCR amplification of human fibroblastic DNA.
U, Rüetschi, L, Rymo, S, Lindstedt
openaire   +2 more sources