Results 111 to 120 of about 32,766 (293)

Two new 2-alkylquinolones, inhibitory to the fish skin ulcer pathogen Tenacibaculum maritimum, produced by a rhizobacterium of the genus Burkholderia sp.

Beilstein Journal of Organic Chemistry, 2018
Exploration of rhizobacteria of the genus Burkholderia as an under-tapped resource of bioactive molecules resulted in the isolation of two new antimicrobial 2-alkyl-4-quinolones.
Dandan Li, Naoya Oku, Atsumi Hasada, Masafumi Shimizu, Yasuhiro Igarashi   +4 more
doaj   +1 more source

Studies on Compounds of Medicinal Interest [PDF]

, 2008
Not ...
Surani, Janak J.
core  

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Previous use of quinolones: A surrogate marker for first line anti-tuberculosis drugs resistance in HIV-infected patients?

Brazilian Journal of Infectious Diseases, 2012
Objectives: Drug resistant Mycobacterium tuberculosis causes much higher rates of treatment toxicity, failure or relapse, and mortality. We determined the drug resistant profile of Mycobacterium tuberculosis strains isolated from a population of HIV ...
Caroline Deutschendorf, Luciano Z. Goldani, Rodrigo Pires dos Santos   +2 more
doaj  

Environmental modification via a quorum sensing molecule influences the social landscape of siderophore production [PDF]

, 2017
Bacteria produce a wide variety of exoproducts that favourably modify their environment and increase their fitness. These are often termed ‘public goods’ because they are costly for individuals to produce and can be exploited by non-producers (‘cheats’).
College of Science and Engineering, Da Silva, Ana C., Diggle, Stephen P., Easton, Scott A.S., Harrison, Freya, McNally, Luke, Popat, Roman, School of Biological Sciences, SynthSys, Williams, Paul   +9 more
core   +3 more sources

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Alkaloids of the Australian Rutaceae: Lunasia quercifolia. IV. Identification of a minor constituent as 5-Hydroxy-1-methyl-2-phenyl-4-quinolone and the preparation of an angular isomer of ( - )-Lunine [PDF]

, 1968
NK Hart, SR Johns, JA Lamberton, JR Price   +3 more
openalex   +1 more source

Establishment and dietary risk assessment of UPLC-MS/MS detection method for 16 quinolone antibiotics in freshwater fish

Shipin yu jixie
Objective: This study aimed to establish a method for the simultaneous determination of 16 quinolones in freshwater fish by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and then analyze the effect of three different ...
GAO Yunkai, CHENG Chunqian, CHENG Xiaomei, ZHOU Lingyu, DEND Yinglin, YIN Qingchun   +5 more
doaj   +1 more source

Development of a copper-catalyzed amidation-base-promoted cyclization sequence for the synthesis of 2-aryl- and 2-vinyl1-4 quinolones [PDF]

, 2007
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2007.Vita.Includes bibliographical references (p. 45-48).A direct two-step method for the preparation of 2-aryl- and 2-vinyl-4-quinolones that utilizes a copper-catalyzed amidation
Jones, Carrie Preston
core  

Selective Targeting of Tumorigenic Cancer Cell Lines by Microtubule Inhibitors [PDF]

, 2008
For anticancer drug therapy, it is critical to kill those cells with highest tumorigenic potential, even when they comprise a relatively small fraction of the overall tumor cell population.
BA Teicher, G Schatten, GR Pettit, Gus R. Rosania, JN Weinstein, JW Hammond, K Chen, K Chen, KD Paul, Kerby Shedden, KJ Verhey, L Li, L Li, L Ricci-Vitini, M Al-Hajj, M Monga, MR Boyd, Newaj M. Abdullah, PG Wilson, RH Shoemaker, RM Warn, S Westermann, SC Kou, SK Singh, T Reya, Winston Hide, WW van Osdol, Y Xia, Y Xia   +28 more
core   +4 more sources