Results 11 to 20 of about 11,679,551 (275)
Microwave assisted synthesis of 4-quinolones and N,N′-diarylureas
4-Quinolinones are an important class of alkaloids, widely used as conventional drugs to treat various infectious diseases. In this study, we report the synthesis of 4-quinolones in one step, under microwave irradiation and with diphenyl ether as a ...
Duarte Patricia D. +2 more
doaj +2 more sources
Evaluation of the Activity of 4‑Quinolones against Multi-Life Stages of Plasmodium spp. [PDF]
Yasmin Annunciato +31 more
doaj +2 more sources
Bacterial mntagenicity and the 4-quinolones [PDF]
Ian Phillips
openalex +3 more sources
DNA gyrase, topoisomerase IV, and the 4-quinolones
For many years, DNA gyrase was thought to be responsible both for unlinking replicated daughter chromosomes and for controlling negative superhelical tension in bacterial DNA. However, in 1990 a homolog of gyrase, topoisomerase IV, that had a potent decatenating activity was discovered.
K. Drlica, Xilin Zhao
semanticscholar +3 more sources
Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones [PDF]
To describe the chemical structure and characterize physico-chemical properties of organometallic complexes it is necessary to use a complex set of analysis methods. Thus, this review has been compiled as a relevant guide which includes the most commonly
Aura Rusu, Gabriel Hancu, Silvia Imre
doaj +1 more source
4-quinolones as noncovalent inhibitors of high molecular mass penicillin-binding proteins. [PDF]
Shilabin AG +4 more
europepmc +2 more sources
1-Phenyl-2-trifluoromethyl-4-quinolone [PDF]
In the title mol-ecule, C(16)H(10)F(3)NO, the N-bound phenyl ring is oriented nearly orthogonal to the quinolinyl ring in order to avoid steric clashes with the trifluoro-methyl substituent [dihedral angle 89.7 (1)°].
Sadr, Moayad Hossaini +3 more
openaire +4 more sources
4-Quinolone Alkaloids from Melochia odorata [PDF]
The methanol extract of Melochia odorata yielded three 4-quinolone alkaloids including waltherione A (1) and two new alkaloids, waltherione C (2) and waltherione D (3). Waltheriones A and C showed significant activities in an in vitro anti-HIV cytoprotection assay at concentrations of 56.2 and 0.84 μM and inhibition of HIV P24 formation of more than 50%
Raquel C. Jadulco +7 more
openalex +3 more sources
Quinolones are one of the most extensively used therapeutic families of antibiotics. However, the increase in antibiotic-resistant bacteria has rendered many of the available compounds useless.
Beatriz Suay-García +5 more
doaj +1 more source
Pd-NHC catalysed direct sulfenylation and selenylation of 3-iodo-4-quinolones has been developed. This protocol provides an alternative route for the construction of ipso-C–S and C–Se bond formation in 4-quinolones under aerobic conditions.
Prasanjit Ghosh, Sajal Das
doaj +1 more source

