Results 11 to 20 of about 11,679,551 (275)

Microwave assisted synthesis of 4-quinolones and N,N′-diarylureas

open access: yesGreen Processing and Synthesis, 2013
4-Quinolinones are an important class of alkaloids, widely used as conventional drugs to treat various infectious diseases. In this study, we report the synthesis of 4-quinolones in one step, under microwave irradiation and with diphenyl ether as a ...
Duarte Patricia D.   +2 more
doaj   +2 more sources

Evaluation of the Activity of 4‑Quinolones against Multi-Life Stages of Plasmodium spp. [PDF]

open access: yesACS Omega
Yasmin Annunciato   +31 more
doaj   +2 more sources

DNA gyrase, topoisomerase IV, and the 4-quinolones

open access: yesMicrobiology and Molecular Biology Reviews, 1997
For many years, DNA gyrase was thought to be responsible both for unlinking replicated daughter chromosomes and for controlling negative superhelical tension in bacterial DNA. However, in 1990 a homolog of gyrase, topoisomerase IV, that had a potent decatenating activity was discovered.
K. Drlica, Xilin Zhao
semanticscholar   +3 more sources

Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2018
To describe the chemical structure and characterize physico-chemical properties of organometallic complexes it is necessary to use a complex set of analysis methods. Thus, this review has been compiled as a relevant guide which includes the most commonly
Aura Rusu, Gabriel Hancu, Silvia Imre
doaj   +1 more source

1-Phenyl-2-trifluoromethyl-4-quinolone [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2007
In the title mol-ecule, C(16)H(10)F(3)NO, the N-bound phenyl ring is oriented nearly orthogonal to the quinolinyl ring in order to avoid steric clashes with the trifluoro-methyl substituent [dihedral angle 89.7 (1)°].
Sadr, Moayad Hossaini   +3 more
openaire   +4 more sources

4-Quinolone Alkaloids from Melochia odorata [PDF]

open access: greenJournal of Natural Products, 2014
The methanol extract of Melochia odorata yielded three 4-quinolone alkaloids including waltherione A (1) and two new alkaloids, waltherione C (2) and waltherione D (3). Waltheriones A and C showed significant activities in an in vitro anti-HIV cytoprotection assay at concentrations of 56.2 and 0.84 μM and inhibition of HIV P24 formation of more than 50%
Raquel C. Jadulco   +7 more
openalex   +3 more sources

Synthesis of Quinolones and Zwitterionic Quinolonate Derivatives with Broad-Spectrum Antibiotic Activity

open access: yesPharmaceuticals, 2022
Quinolones are one of the most extensively used therapeutic families of antibiotics. However, the increase in antibiotic-resistant bacteria has rendered many of the available compounds useless.
Beatriz Suay-García   +5 more
doaj   +1 more source

Creation of 4-Quinolone Thioether and Selenoether Derivatives via Pd-NHC Catalysed Cross-Coupling Reaction

open access: yesSynOpen, 2020
Pd-NHC catalysed direct sulfenylation and selenylation of 3-iodo-4-quinolones has been developed. This protocol provides an alternative route for the construction of ipso-C–S and C–Se bond formation in 4-quinolones under aerobic conditions.
Prasanjit Ghosh, Sajal Das
doaj   +1 more source

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