Results 21 to 30 of about 11,679,551 (275)

4-Quinolone fused heterocyclic ring systems by intramolecular reactions of 4-quinolone-2-carboxamides [PDF]

open access: yesTetrahedron, 2014
Abstract A versatile synthetic route to new 4-quinolone-based polycyclic systems is described. TFA-catalyzed intramolecular reaction of N-unsubstituted quinolone-2-carboxylic acid amides gives structurally diverse compounds, depending on the length of the chain.
R. Cincinelli   +3 more
openaire   +2 more sources

Effect of Co-Existing Cations and Anions on the Adsorption of Antibiotics on Iron-Containing Minerals

open access: yesMolecules, 2022
The adsorption of antibiotics on minerals is an important process in their environment behavior. The adsorption behavior of antibiotics on iron-containing minerals and the effect of co-existing cations and anions were studied in this work.
Xiaoyu Guan   +6 more
doaj   +1 more source

The determination of six quinolone drug residues in milk tofu by high-performance liquid chromatography-tandem mass spectrometry

open access: yesZhongguo shipin weisheng zazhi, 2023
ObjectiveTo establish a high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the detection of 6 quinolones residues in milk tofu.MethodsThe milk tofu sample was extracted with 0.1 mmol/L EDTA-Mcllvaine buffer with 0.1 ...
WANG Xueqi   +5 more
doaj   +1 more source

Waltherione C and cleomiscosin from Melochia umbellata var. Degrabrata K. (Malvaceae), biosynthetic and chemotaxonomic significance [PDF]

open access: yes, 2014
Waltherione C, a 4-quinolinone secondary metabolite, and cleomiscosin have been isolated from Melochia umbellata (Malvaceae).A biosynthetic scheme incorporating the unique 4-pyridones and 4-quinolones isolated from Melochia and Waltheria spp.
Noor, Alfian, Soekamto, Nunuk H.
core   +1 more source

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]

open access: yes, 2017
Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio   +8 more
core   +2 more sources

The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]

open access: yes, 2003
Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E   +7 more
core   +1 more source

Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones

open access: yesMolecules, 2019
Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-c:5,6-c′]difuro[2,3-c:4,5-c′]-diquinoline-6,14(5H,12H)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[d]oxazol-2-yl)-3-hydroxy-1H ...
Ashraf A. Aly   +7 more
doaj   +1 more source

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. coli and K. pneumoniae, A. baumannii and P. aeruginosa: A Global Ecological Analysis

open access: yesAntibiotics, 2021
(1) Background: It is unclear what underpins the large global variations in the prevalence of fluoroquinolone resistance in Gram-negative bacteria. We tested the hypothesis that different intensities in the use of quinolones for food-animals play a role.
Chris Kenyon
doaj   +1 more source

Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion

open access: yesMolecules, 2022
Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical evolution, leading to death.
Amanda Rodrigues Pinto Costa   +8 more
doaj   +1 more source

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