Results 201 to 210 of about 48,547 (334)

Crystal structure of 1,3,5-tris(4-methoxyphenyl)-1H-1,2,4-triazole-2- oxide, C23H21N3O4 [PDF]

, 2005
Wolfgang Frey, J. Y. Lee, V. Jäger
openalex   +1 more source

Design and Synthesis of Triazole‐Based p‐tert‐Butylcalix[4]Arene Conjugates and Evaluation of Their Antimicrobial, Antibiofilm, and Anti‐Quorum‐Sensing Activities

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Macrocyclic calix[n]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p‐tert‐butylcalix[4]arene conjugates (AT10a and AT10b) and their p‐tert‐butylphenol analogs (AT10b and AT11b ...
Alfred Ngenge Tamfu, Selahattin Bozkurt, Ozgur Ceylan   +2 more
wiley   +1 more source

Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series

British Journal of Clinical Pharmacology, EarlyView.
Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen, Aurelia H. M. de Vries Schultink, Bas J. M. Peters, Dieuwertje Ruigrok, Rob H. J. Schönwetter, Esther V. Uijtendaal, Maaike A. Sikma   +6 more
wiley   +1 more source

Synthesis and Biological Activities of Some 2‐(Substituted‐phenyl)‐2‐methyl‐4‐ (1,2,4‐triazole‐1‐yl)methane‐1,3‐dioxolane Derivatives. [PDF]

, 2005
Fang‐Fang Jian, Hailian Xiao, Liang-Zhong Xu, Guan-Ping Yu   +3 more
openalex   +1 more source

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation

Cancer Communications, EarlyView.
Abstract Radiopharmaceuticals are reshaping the landscape of cancer therapy, offering a unique theranostic advantage that is becoming increasingly central to precision medicine. By labeling the same molecular scaffold with different radionuclides, these agents enable seamless integration of diagnostic imaging and targeted therapy.
Jing Li, Xuejun Wen, Rebeka Rita Reszegi, Hemavarshini Kamalrhaj, Wolfgang J. Parak, Xiaoyuan Chen, Jingjing Zhang   +6 more
wiley   +1 more source

Synthesis of Alkyl 1-(Substituted Pyridin-2-yl)-1H-1,2,3-triazole-4-carboxylates by ‘Ring Switching’ Transformation of 4-Oxo-4H-pyridino[1,2-a]pyrimidine-3-diazonium Tetrafluoroborates

, 2000
Branko Stanovnik, Simon Rečnik, Jurij Svete, Anton Meden   +3 more
openalex   +1 more source

Synthetic Studies Toward Aryl‐(4‐aryl‐4H‐[1,2,4]triazole‐3‐yl)‐amine from 1,3‐Diarylthiourea as Urea Mimetics. [PDF]

, 2005
Amarnath Natarajan, Yuhong Guo, Haribabu Arthanari, Gerhard Wagner, José A. Halperin, Michael Chorev   +5 more
openalex   +1 more source

Harnessing Nature: Computational and Experimental Insights Into Ipomoea obscura Metabolites for Bladder Cancer Therapy

Chemistry &Biodiversity, EarlyView.
ABSTRACT Ipomoea obscura (L.), a medicinal plant from the Convolvulaceae family, has been traditionally used to treat various ailments. This study evaluated the in vitro cytotoxicity of its ethanolic leaf extract against human bladder cancer T24 cells and investigated its phytochemical constituents through computational methods.
Saravana Prabha Poochi, Rajamanikandan Sundarraj, Manikandan Vani Raju, Meenakshi Kaniyur Chandrasekaran, Rathi Muthaiyan Ahalliya, Chella Perumal Palanisamy, Gopalakrishnan Velliyur Kanniappan, Benod Kumar Kondapavuluri, Muthu Thiruvengadam   +8 more
wiley   +1 more source

Design, Synthesis, and Molecular Docking of Triazole‐Coumarin Hybrids as Potent Breast Cancer Inhibitors Targeting Cell Cycle and Apoptosis

Chemistry &Biodiversity, EarlyView.
Triazole‐coumarin hybrids were synthesized as breast cancer inhibitors. Derivative 5f induced S‐phase arrest and apoptosis in cancer cells, with minimal toxicity to healthy cells, showing promise for anticancer drug development. ABSTRACT Breast cancer continues to pose a significant global health burden, highlighting the urgent need for novel ...
Murat Keser, Emre Menteşe, Suleyman Ilhan, Mustafa Emirik, Harika Atmaca   +4 more
wiley   +1 more source

Corrosion behavior and inhibition of nickel in sulfuric acid solutions using triazole derivatives: insights from electrochemical and surface analysis. [PDF]

Sci Rep
Saleh MGA, Alfaker M, Hawsawi H, Al-Juaid SS, Alabdali FH, Abdelfattah M, Abdallah M, El Wanees SA.   +7 more
europepmc   +1 more source