1‑Iodobuta-1,3-diynes in Copper-Catalyzed Azide–Alkyne Cycloaddition: A One-Step Route to 4‑Ethynyl-5-iodo-1,2,3-triazoles [PDF]
, 2019 Cu-catalyzed 1,3-dipolar cycloaddition of iododiacetylenes with organic azides using iodotris(triphenylphosphine)copper(I) as a catalyst was found to be an efficient one-step synthetic route to 5-iodo-4-ethynyltriazoles. The reaction is tolerant to
Anastasia I. Govdi (6282167) +3 more
core +7 more sources
Synthesis and antibacterial evaluation of sulfonamide bridged disubstituted 1,2,3-triazoles [PDF]
, 2022 In the present study, a series of sulfonamide bridged 1,4-disubstituted 1,2,3-triazoles have been synthesized in good yield via click reaction between sulfonamide linked terminal alkynes and in situ prepared 2/3/4-azidobenzenesulfonamides.
C. P. Kaushik (7494545) +1 more
core +1 more source
Access to Fluoroalkylated Azoles and 2Acylaminoketones via Fluorinated Anhydride-Mediated Cleavage of NH-1,2,3-Triazoles [PDF]
, 2022 NH-1,2,3-Triazoles undergo a ring cleavage in reactions with fluorinated acid anhydrides (trifluoroacetic, difluoroacetic, chlorodifluoroacetic, and pentafluoropropionic anhydrides) by nitrogen acylation and acid-mediated triazole ring opening ...
Petr Beier (1748218) +3 more
core +1 more source
Metal-Free Synthesis of 1,5-Disubstituted 1,2,3-Triazoles [PDF]
, 2021 A three-component synthesis of 1,5-disubstituted 1,2,3-triazoles from α-acetyl-α-diazomethane sulfonamides, primary aliphatic amines, and aromatic aldehydes is presented.
Mikhail Krasavin +9 more
core +1 more source
Catalytic Asymmetric Synthesis of Atropisomeric N‑Aryl 1,2,4-Triazoles [PDF]
, 2023 The atroposelective synthesis of N-aryl 1,2,4-triazoles was developed. A cyclodehydration reaction was rendered asymmetric with the use of a chiral phosphoric acid catalyst to afford atropisomeric N-aryl 1,2,4-triazoles in up to 91:9 er ...
Sooyun Choi (13103816) +7 more
core +3 more sources
Generation of Functionalized Azepinone Derivatives via a (4 + 3)-Cycloaddition of Vinyl Ketenes and Imino Carbenes Derived from NSulfonyl-triazoles [PDF]
, 2022 An intermolecular RhII-catalyzed, formal (4 + 3)-cycloaddition between vinyl ketenes and N-sulfonyl-1,2,3-triazoles for the construction of azepinone products is described.
Brandon L. Ashfeld (1701802) +9 more
core +1 more source
Synthesis of 1‑Cyanoalkynes and Their Ruthenium(II)-Catalyzed Cycloaddition with Organic Azides to Afford 4‑Cyano-1,2,3-triazoles [PDF]
, 2018 A new method to convert terminal alkynes under relatively mild conditions to 1-cyanoalkynes using in situ formed cyanogen is described. 1-Cyanoalkynes have a higher reactivity than terminal alkynes in the ruthenium(II)-catalyzed regiospecific azide ...
Peiye Liu (3226191) +2 more
core +3 more sources
Design, synthesis, characterization and antimicrobial evaluation of amide tagged 1,4-disubstituted 1,2,3-triazoles [PDF]
, 2023 A series of amide tagged 1,4-disubstituted 1,2,3-triazole has been designed and synthesized in good yield through Cu (I) catalyzed click chemistry strategy.
C. P. Kaushik (7494545) +3 more
core +1 more source
Synthesis, characterization and antibacterial activity of the thioether linked 1,2,3-triazoles [PDF]
, 2021 A green synthetic approach for the expedite construction of thirty six thioether linked 1,2,3-triazoles was carried out using Cellulose supported CuI nanoparticles in water.
Jyoti Sangwan (7494548) +1 more
core +1 more source
p-Toluenesulfonic acid-promoted autocatalytic hydrolyzation of 1-tosyl-1,2,3-triazoles [PDF]
, 2018 The first example of autocatalytic hydrolyzation of 4-aryl-1-tosyl-1,2,3-triazoles induced by p-toluenesulfonic acid was reported, providing an effective and metal-free synthetic approach to deliver a broad range of new 4-aryl-2H-1,2,3-triazoles in good ...
Dongdong Zhang (644246) +7 more
core +1 more source