Results 41 to 50 of about 12,877,669 (294)

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +2 more sources

Facile One-Pot Parallel Synthesis of 3‑Amino-1,2,4-triazoles

, 2018
A 1,2,4-triazole motif is present in numerous commercialized and investigational bioactive molecules. Despite its importance for medicinal chemistry, there is a lack of convenient combinatorial approaches toward this molecular core.
Sergey E. Pipko (1514257), Andrey V. Bogolyubsky (5408150), Mykhailo Vybornyi (1486132), Volodymyr S. Brovarets (5408144), Anton V. Zhemera (1514260), Alexander V. Grishchenko (5408153), Anzhelika I. Konovets (1514263), Roman O. Doroshchuk (5408147), Dmytro N. Khomenko (5408156), Yurii S. Moroz (119826), Olena Savych (4721310)   +10 more
core   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Synthesis, Evaluation and Characterization of Some 1,3,4-Triazole-2-one Derivatives as Antimicrobial Agents

E-Journal of Chemistry, 2012
A series of novel compounds like 3[(phenyl substituted)-5-methyl-1(Benzosulphonylamine)]-1,3,4-triazole-2-ones II(a-f) were synthesized by treating 4-amino-1-phenyl-3-methyl-5-oxo-1,2,4-triazoles with benzene sulphonyl chloride using pyridine as solvent.
Mahabaleshwaraiah Neelgundmath, Oblennavar Kotresh   +1 more
doaj   +1 more source

Syntheses, Characterization and Biological Activity of Some 1, 2, 4‐Triazole Derivatives [PDF]

Journal of Chemistry, 2009
Syntheses of a series of 3‐alkyl‐4‐ amino‐5‐ cyanomethyl‐4H‐1, 2, 4‐triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa.
R. J. Singh, D. K. Singh
openaire   +2 more sources

Facile synthesis of copper(I) salicylate and its use in the selective synthesis of 1-acyloxy-1,2,3-triazoles and 1-sulfonyl-1,2,3-triazoles

, 2022
The straightforward synthesis of copper(I) salicylate from salicylic acid and copper(I) oxide is described for the first time and its identity confirmed by XPS and XRDP techniques.
Uvaldo Hernández-Balderas (12697926), Juan José García-Vanegas (12697920), David Morales-Morales (1737595), Alejandro Cervantes-Reyes (10823533), Gustavo Lopez-Téllez (12697923), Marco Antonio García-Eleno (12697929), Erick Cuevas-Yañez (544471)   +6 more
core   +1 more source

Enhanced Mechanical Recycling of Polymer Mixtures by a Trifunctional Dynamic Crosslinker

Advanced Materials, EarlyView.
A self‐catalyzed, trifunctional dynamic crosslinker that incorporates three desired properties into one system and is compatible with reactive extrusion can compatibilize waste plastic mixtures containing high Tm polymers and impart the recycled mixtures with superior thermoset properties such as enhanced creep resistance and thermomechanical stability
Xavier Westworth, Essa Shamsan, Yunpeng Gao, Nevaya Carr, Eugene Y.‐X. Chen   +4 more
wiley   +1 more source

Carbohydrate‐Directed Labeling Probes for UV‐Independent Chemoproteomic Profiling of Carbohydrate–Protein Interactions

Angewandte Chemie, EarlyView.
Modular carbohydrate‐directed labeling probes (CDLPs) convert weak carbohydrate–protein interactions into durable covalent tags in live cells without the need for multivalency or UV irradiation. Ligand binding triggers proximity‐enabled, glycan‐releasing acyl transfer to install a click handle for protein tagging and chemoproteomic profiling.
Matthew C. Russolillo, Wariya Nirachonkul, Nora Ross, Rahul M. Hedau, Zachary Clark, Michaella J. Rekowski, Michael P. Washburn, Mark P. Farrell   +7 more
wiley   +2 more sources

Fast and Efficient Synthesis of Fluoro Phenyl 1,2,3-Triazoles via Click Chemistry with Ultrasound Irradiation and Their Biological Efficacy Against Candida albicans

Organics
Several fluoro phenyl triazoles were synthesized using click chemistry between fluoro phenyl azides and phenyl acetylene. Under ultrasound irradiation, this synthetic procedure was performed with Cu (I) in the presence of 1,10-phenanthroline.
Elisa Leyva, Johana Aguilar, Silvia E. Loredo-Carrillo, Ismael Acosta-Rodríguez   +3 more
doaj   +1 more source

SYNTHESIS AND ANTIBACTERIAL EVALUATION OF CERTAIN 1,2,4- TRIAZOLE AND THIAZOLID INONE DERIVATIVES

Zagazig Journal of Pharmaceutical Sciences, 1993
The synthesis of certain 3 - (4- chloro - 3,5 - đimethyl - phenoxy ) methyl 4-alkyl or aryl -5 mercapto - 1,2,4 - triazoles ( 5a - e) is described.
Awatef Farag , Safinaz Abbas , Anwar Mikhael, Mona Abdel Messeh   +3 more
doaj   +1 more source