Results 51 to 60 of about 25,084 (189)

Regioselective Synthesis of New Family of 2-Substituted 1,2,3-Triazoles and Study of Their Fluorescent Properties

Molecules, 2023
Modification of 5-aryl-4-trifluoroacetyltriazoles at the NH-moiety was investigated. Screening of the alkylation conditions revealed that using Na2CO3 as a base and DMF as a solvent of 2-substituted triazoles can be preferentially prepared in up to 86 ...
Vasiliy M. Muzalevskiy, Zoia A. Sizova, Valentine G. Nenajdenko   +2 more
doaj   +1 more source

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME (2-AMINO-5-THIOL-1, 3, 4-THIADIAZOLE DERIVATIVES [PDF]

, 2021
Five derivatives of thiadiazole were prepared with aldehydes and alkyl halides, compoundA: 2-amino-5-thiol-1,3,4- thiadiazole, compound B :2-(o-hydroxybenzylidine)amino-5-thiol-1,3,4-thiadiazole, compoundC: 2(2-butan-lidine)amino-5-thiol-1,3,4 ...
AL-Joubori, Sabiha F-, Saleh, Mohammed M., Thamiar, Boushra F A-   +2 more
core   +1 more source

The research of acute toxicity of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Introduction. The process of new drugs creating includes a plurality of stages, which allow their application in medical practice in the future. These studies are a guarantee of the effectiveness and safety of the test compounds.
I. I. Аksyonova-Seliuk, Ye. S. Pruglo, O. I. Panasenko, Ye. G. Knysh   +3 more
doaj   +1 more source

Analysis of the relationship between the predicted biological activity and the chemical structure of S-derivatives of 5-(5-bromofuran-2-yl)-4R-1,2,4-triazole-3-thiols

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
1,2,4-Triazole derivatives are actively used as components in the development of new drugs, plant protection products, polymeric materials, anti-corrosion agents and etc.
O. A. Bigdan
doaj   +1 more source

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 1, 2, 4-TRIAZOLE DERIVATIVES [PDF]

, 2014
Objectives: To synthesize, characterize and evaluate antimicrobial properties of some 1, 2, 4-triazole derivatives. Methods: A novel series of 1, 2, 4-Triazole derivatives (D-1-D-8) had been synthesized.
Maurya, Roopesh Kumar, Pal, Dilipkumar, Pandey, Desh Deepak, Singh, Vipul   +3 more
core  

Acute toxicity of 3-(2-, 3-fluorophenyl)-6-(aryl-, hetaryl)-[1,2,4]triazole[3,4-b][1,3,4]thiadiazoles

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Nowadays an attempt to create a number of new biologically active compounds by many scientific groups is being one of the topical issues in the domestic pharmaceutical industry.
O. A. Bihdan, V. V. Parchenko
doaj   +1 more source

Synthesis and Spectral Study of a New Family of 2,5-Diaryltriazoles Having Restricted Rotation of the 5-Aryl Substituent

Molecules, 2020
Efficient synthesis of 2,5-diaryl substituted 4-azido-1,2,3-triazoles by the reaction of sodium azide with dichlorosubstituted diazadienes was demonstrated.
Biligma Tsyrenova, Valentine Nenajdenko
doaj   +1 more source

Reaction strategies for synthesis of imidazole derivatives: a review [PDF]

, 2018
The development of a methodical directional synthesis of complex organic molecules with the aim of obtaining the physiologically active substance with selective action takes a central position in modern synthetic organic chemistry.
Atanasova-Stamova, Sylvia Yordanova, Georgieva, Maya Boyanova, Georgieva, Svetlana Fotkova   +2 more
core   +2 more sources

Fluorescent calix[4]triazole for selective fluoride anion sensing

RSC Advances
The selective recognition ability of pyrene-calix[4]triazole conjugate for F− was demonstrated through fluorescence quenching based on the PET mechanism.
Jihee Cho, Sanghee Kim
openaire   +2 more sources

Access to Substituted Tricyclic Heteroarenes by an Oxidative Cyclization Reaction and Their Antifungal Performance

Pharmaceuticals
Background/Objectives: Fungal pathogens are increasingly developing concerning resistance against the currently available antifungal drugs, which creates a constant demand for new antifungal agents.
Rehema Nakiwala, Noopur Dasgupta, Rebecca Wilson, Erika I. Lutter, Jeanne L. Bolliger   +4 more
doaj   +1 more source