Results 81 to 90 of about 12,458,805 (285)
BackgroundThe ongoing treatment modalities for breast cancer (BC) primarily rely on the expression status of ER, PR and HER-2 receptors in BC tissues. Our strategy of chemosensitization provides new insights to counter chemoresistance, a major obstacle ...
Sreekumar U. Aiswarya (11136633) +18 more
core +1 more source
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source
5-FU resistant CRC-PDX samples exhibit increased Rpl22L1 staining.
A. Representative picture from a TMA constructed using CRC PDX samples reveals that RPL22L1 is highly expressed in CRC PDX samples compared with normal colon (20X magnification).
Jens Hoffmann (222702) +8 more
core +1 more source
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Background. The aims of this study were to analyze the clinical characteristics of SPM in patients with well-differentiated thyroid cancer and to determine the long-term prognosis in patients with double malignancies. Materials and Methods.
Miaw-Jene Liou +4 more
doaj +1 more source
Transdermal delivery of 5-fluorouracil (5-FU) by 1-alkylcarbonyl-5-FU prodrugs
The members of a series of 1-alkylcarbonyl-5-FU prodrug derivatives have been characterized and evaluated for their abilities to deliver 5-FU into and through skin. There was no correlation of lipid solubility or partition coefficient with relative abilities of the members of the 1-alkylcarbonyl series to deliver 5-FU through skin. However, there was a
Department of Medicinal Chemistry, P.O. Box 100485, University of Florida, Gainesville, FL 32610, USA ( host institution ) +2 more
openaire +2 more sources
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
This study aimed to investigate the possible histopathological and immunohistochemical effects of bovine colostrum (BC) against the toxic effects of 5-fluorouracil (5-FU) on the liver, kidney, and heart of Wistar Albino rats.
Muhammet Bahaeddin Dörtbudak +4 more
doaj +1 more source
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau +8 more
wiley +1 more source
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source

