Results 91 to 100 of about 52,894 (243)

Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer

International Journal of Endocrinology, 2016
Background. The aims of this study were to analyze the clinical characteristics of SPM in patients with well-differentiated thyroid cancer and to determine the long-term prognosis in patients with double malignancies. Materials and Methods.
Miaw-Jene Liou, Ngan-Ming Tsang, Chuen Hsueh, Tzu-Chieh Chao, Jen-Der Lin   +4 more
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Chimeric Antigen Receptor Cell Therapy: Empowering Treatment Strategies for Solid Tumors

Current Issues in Molecular Biology
Chimeric antigen receptor-T (CAR-T) cell therapy has demonstrated impressive efficacy in the treatment of blood cancers; however, its effectiveness against solid tumors has been significantly limited.
Tang-Her Jaing, Yi-Wen Hsiao, Yi-Lun Wang   +2 more
doaj   +1 more source

Influence of 5-fluorouracil-loaded microsphere formulation on efficient rat glioma radiosensitization [PDF]

, 2004
PURPOSE: To determine (i) the efficiency of radiosensitizing 5-FU-loaded microspheres and (ii) the impact of microparticle formulation on response to treatment.
E. Gamelin, J.P. Benoît, J.P. Cueyssac, L. Lemaire, M. Mege, M.C. Venier-Julienne, P. Menei, V.G. Roullin   +7 more
core   +4 more sources

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Comparative evaluation of the My5-FU™ immunoassay and LC-MS/MS in monitoring the 5-fluorouracil plasma levels in cancer patients [PDF]

, 2017
Background: Chemotherapies of solid tumors commonly include 5-fluorouracil (5-FU). With standard doses of 5-FU, substantial inter-patient variability has been observed in exposure levels and treatment response.
Aebi, Yolanda, Büchel, Barbara, Joerger, Markus, Largiadèr, Carlo R., Schürch, Stefan, Sistonen, Johanna   +5 more
core  

Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells [PDF]

, 2007
Background Hepatocellular carcinoma (HCC) is the most invasive and frequently diagnosed malignancy and the second leading cause of cancer death in many regions of Asia. The PI3K/Akt/mTOR signal pathway is involved in multiple cellular functions including
Xinxin Bu, Fengqi Jia, Weifeng Wang, Xianling Guo, Mengchao Wu, Lixin Wei, HB El-Serag, P Blume-Jensen, SR Datta, EJ Brown, MI Chiu, DM Sabatini, EJ Brown, PE Burnett, S Isotani, HB Jefferies, HB Jefferies, JC Lawrence Jr, D Rousseau, Y Shi, Y Shi, N Terada, FC Nielsen, IB Rosenwald, M Castedo, M Muller, CM Counter, C Mehle, GB Morin, CM Counter, NW Kim, JW Shay, K Nagao, T Gerelsaikhan, V Gorbunova, G Saretzki, E Erbay, L Shu, E Jacinto, RC Braun-Dullaeus, M Guba, JH Choi, PJ Houghton, AC Gingras, S Huang   +44 more
core   +2 more sources

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: a Southern Italy Cooperative Oncology Group phase III trial [PDF]

, 2005
The primary end point of this phase III trial was to compare the response rate (RR) of oxaliplatin (OXA) plus levo-folinic acid (l-FA) and 5-fluorouracil (5-FU) bolus with that of irinotecan (IRI) plus l-FA and 5-FU bolus in advanced colorectal ...
Buzzi, F, Comella, P, De Lucia, L, De Vita, F, Farris, A, Filippelli, G, Leo, S, Lorusso, V, Maiorino, L, Mancarella, S, Massidda, B, Natale, D, Palmeri, S, Roselli, M, Tafuto, S   +14 more
core   +3 more sources