Results 81 to 90 of about 27,791 (179)
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.This graphical summary illustrates the efficacy and safety of brexpiprazole (2–4 mg) in patients with schizophrenia. The meta‐analysis demonstrates significant improvement in clinical outcomes, with reductions in Positive and Negative Syndrome Scale (PANSS) and Clinical Global Impression ‐ Severity scale (CGI‐S) scores, indicating better symptom ...
Sher Bano +14 more
wiley +1 more source
eLife, 2018 Background: Lysergic acid diethylamide (LSD) has agonist activity at various serotonin (5-HT) and dopamine receptors. Despite the therapeutic and scientific interest in LSD, specific receptor contributions to its neurobiological effects remain unknown ...
Katrin H Preller +11 more
doaj +1 more source
The effect of 5-HT2A receptor stimulation on morphine withdrawal symptoms in mice [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2023 Background and Aim: Serotonergic system has a role in morphine dependence and withdrawal symptoms via its receptors. On the other hand, the effect of 5-HT2A receptor on withdrawal symptoms has not been evaluated completely.
Nasrin Hashemi-Firouzi +4 more
doaj
Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems +5 more
wiley +1 more source
Dual role of endogenous serotonin in 2,4,6-trinitrobenzene sulfonic acid-induced colitis
Frontiers in Pharmacology, 2016 Background and Aims: Changes in gut serotonin content have been described in Inflammatory Bowel Disease and in different experimental models of colitis: the critical role of this monoamine in the pathogenesis of chronic gastrointestinal inflammation is ...
Alberto eRapalli +7 more
doaj +1 more source
Evidence of complex involvement of serotonergic genes with restrictive and binge purge subtypes of anorexia nervosa [PDF]
, 2010 Peer ...
Blundell, John E. +5 more
core +1 more source
Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1287-1308, May 2026.The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou +2 more
wiley +1 more source
Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans [PDF]
, 2018 Rationale: Binocular rivalry occurs when different images are simultaneously presented to each eye. During continual viewing of this stimulus, the observer will experience repeated switches between visual awareness of the two images.
Carter, Olivia +5 more
core
M3 muscarinic acetylcholine receptor facilitates the endocytosis of mu opioid receptor mediated by morphine independently of the formation of heteromeric complexes [PDF]
, 2017 Morphine inefficiency to induce the internalization of mu opioid (MOP) receptors observed in numerous experimental models constitutes a paradigm of G-protein coupled receptor (GPCR) functional selectivity.
Alvarez-Curto, Elisa +2 more
core +1 more source
Arthritis &Rheumatology, Volume 78, Issue 4, Page 985-992, April 2026.Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty +4 more
wiley +1 more source