Results 81 to 90 of about 167,106 (231)
Dual role of endogenous serotonin in 2,4,6-trinitrobenzene sulfonic acid-induced colitis
Frontiers in Pharmacology, 2016 Background and Aims: Changes in gut serotonin content have been described in Inflammatory Bowel Disease and in different experimental models of colitis: the critical role of this monoamine in the pathogenesis of chronic gastrointestinal inflammation is ...
Alberto eRapalli +7 more
doaj +1 more source
The effect of 5-HT2A receptor stimulation on morphine withdrawal symptoms in mice [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2023 Background and Aim: Serotonergic system has a role in morphine dependence and withdrawal symptoms via its receptors. On the other hand, the effect of 5-HT2A receptor on withdrawal symptoms has not been evaluated completely.
Nasrin Hashemi-Firouzi +4 more
doaj
Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
British Journal of Pharmacology, Volume 183, Issue 14, Page 4006-4021, July 2026.Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 14, Page 4022-4047, July 2026.Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Serotonin receptor mechanisms in anti-depressant action
, 2003 Bibliography: leaves 221-270.Serotonin neurones have been implicated in the pathophysiology and treatment of clinical depression to a greater degree than any other neurotransmitter.
Quested, Digby John
core
Personalised Perception: The Effect of Personality on the Sensory Effects of Psychedelics
Drug and Alcohol Review, Volume 45, Issue 5, July 2026.ABSTRACT Introduction Psychedelics induce a wide range of sensory distortions and hallucinations (henceforth ‘distortions’). Yet, little is known about factors that influence the occurrence of certain distortions. Extra‐pharmacological variables including personality traits have been found to correlate with the occurrence of different subjective ...
Alexander Boardman +2 more
wiley +1 more source
Human Brain Mapping, Volume 47, Issue 9, June 15, 2026.To determine what drives the responses of the visual claustrum zone, we extracted physical features and collected participants' subjective ratings of naturalistic videos. Claustrum activity was associated with motion, but also with subjective ratings of arousal, valence, and interest, implying the human claustrum's role beyond sensory processing ...
Adam Coates +8 more
wiley +1 more source
Autism Research, Volume 19, Issue 6, June 2026.ABSTRACT Cortical thickness (CT) differences between autistic individuals (AI) and neurotypical controls have been consistently reported, yet the neurochemical mechanisms underlying these differences remain insufficiently understood. Neurotransmitter receptor systems exhibit distinct spatial distributions across the cortex and influence synaptic ...
Livio Tarchi +9 more
wiley +1 more source
Frontiers in NeuroscienceIntroductionStudies suggest that serotonin (5-HT) plays an important role in alcohol use disorder (AUD). While several receptor subtypes modulate the role of 5-HT in AUD, evidence suggests that 5-HT2A and 5-HT2C receptors may be directly involved in ...
Sandy C. Simões +15 more
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.This study reveals that 5‐hydroxytryptamine (5‐HT) synapses in the spinal cord and 5‐HT neurons in the brainstem of the SOD1‐G93A amyotrophic lateral sclerosis (ALS) mouse model are significantly altered, showing a decrease in pre‐symptomatic stages but a marked increase as the disease progresses.
Lijun Zhou +7 more
wiley +1 more source