Results 101 to 110 of about 167,106 (231)

Receptor interaction profiles of 4-alkoxy-2,6-dimethoxyphenethylamines (Ψ derivatives) and related amphetamines

Frontiers in Pharmacology
Background4-substituted 2,6-dimethoxyphenethylamines and the corresponding amphetamines (so-called pseudo [Ψ] derivatives) are a hitherto mostly unexplored group of psychedelics.
Karolina E. Kolaczynska, Karolina E. Kolaczynska, Daniel Trachsel, Marius C. Hoener, Matthias E. Liechti, Matthias E. Liechti, Dino Luethi, Dino Luethi   +7 more
doaj   +1 more source

The 5-HT2A receptor antagonist M100907 produces antiparkinsonian effects and decreases striatal glutamate

Frontiers in Systems Neuroscience, 2011
5-HT plays a regulatory role in voluntary movements of the basal ganglia and have a major impact on disorders of the basal ganglia such as Parkinson’s disease (PD).
Twum eAnsah, Marcus eFerguson, Tultul eNayyar   +2 more
doaj   +1 more source

Expression of 5-Hydroxytryptamine Receptors in Human Urinary Bladders with Benign Prostatic Hyperplasia [PDF]

, 2015
Introduction: This study investigated the mRNA expression pattern and distribution of 5-hydroxytryptamine (5-HT) receptors 5-HT2A, 5-HT2B, 5-HT3A, 5-HT4, and 5-HT7 within the urothelium and detrusor of normal bladder tissue and in the urothelium of ...
Minagawa, Tomonori, Nakazawa, Masaki, Ishizuka, Osamu, Yokoyama, Hitoshi, Kurizaki, Yoshiki, Hiragata, Shiro, Ishikawa, Masakuni, Imamura, Tetsuya, Ogawa, Teruyuki, Nishizawa, Osamu   +9 more
core   +1 more source

Vortioxetine–Lurasidone Augmentation for Compulsive Scratching Behavior in Prader–Willi Syndrome: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This graphical abstract illustrates a case of Prader–Willi syndrome with compulsive scratching behavior, in which augmentation with lurasidone following vortioxetine treatment resulted in marked symptom improvement. The case highlights a potential pharmacological approach for obsessive‐compulsive–related behaviors in Prader–Willi syndrome.
Yasuhide Nagoshi
wiley   +1 more source

Efficacy and safety of 2–4 mg brexpiprazole in the management of schizophrenia: A systematic review and meta‐analysis

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
This graphical summary illustrates the efficacy and safety of brexpiprazole (2–4 mg) in patients with schizophrenia. The meta‐analysis demonstrates significant improvement in clinical outcomes, with reductions in Positive and Negative Syndrome Scale (PANSS) and Clinical Global Impression ‐ Severity scale (CGI‐S) scores, indicating better symptom ...
Sher Bano, Aashan Ahmad, Abdul Haseeb Mohammed, Ismailova Rushana Nurbekovna, Saja Saad, Noor Fatima, Muhammad Bilal Akbar, Zainab Salahuddin, Sadikun Nabi, Mohammad Mustafa Ababneh, Laiba Ajmal, Sidra Hariss, Hiba Manaf, Farah Saleh, Raouf Khan   +14 more
wiley   +1 more source

Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems, Erin E. Sullivan, Ryan P. McGlynn, Praveen Kulkarni, Craig F. Ferris, Raymond G. Booth   +5 more
wiley   +1 more source

Behavioral Effects of Systemic, Infralimbic and Prelimbic Injections of a Serotonin 5-HT2A Antagonist in Carioca High- and Low-Conditioned Freezing Rats

Frontiers in Behavioral Neuroscience, 2017
The role of serotonin (5-hydroxytryptamine [5-HT]) and 5-HT2A receptors in anxiety has been extensively studied, mostly without considering individual differences in trait anxiety.
Laura A. León, Laura A. León, Laura A. León, Vitor Castro-Gomes, Santiago Zárate-Guerrero, Karen Corredor, Antonio P. Mello Cruz, Marcus L. Brandão, Fernando P. Cardenas, J. Landeira-Fernandez   +9 more
doaj   +1 more source

Harm avoidance and 5-HT2A receptors: A brain imaging study

European Psychiatry, 1998
no abstract ...
D'Haenen, Hugo, Baeken, Chris, Flamen, Patrick, Mertens, John, Terriere, Dirk, Chavatte, Kris, Boumon, Rony, Bossuyt, Axel   +7 more
openaire   +2 more sources

The therapeutic role of 5-HT1A and 5-HT2A receptors in depression

, 2004
Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC446220/[EN]The selective serotonin reuptake inhibitors (SSRIs) are the most frequently prescribed antidepressant drugs, because they are well tolerated and have no severe side effects.
Adell, Albert, Artigas, Francesc, Celada, Pau, Amargós-Bosch, Mercè, Puig, M. Victoria   +4 more
core  

Loop B is a major structural component of the 5-HT3 receptor [PDF]

, 2008
The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F).
Thompson, Andrew J., Thompson, A.J., M. Lochner, Lummis, S. C. R., Lummis, S.C.R., S. C. R. Lummis, Lochner, M., A. J. Thompson, Lochner, Martin, Thompson, Andrew James   +9 more
core   +1 more source