Results 11 to 20 of about 9,465,904 (238)

Preparation and characterization of 6-mercaptopurine-coated magnetite nanoparticles as a drug delivery system [PDF]

Drug Design, Development and Therapy, 2013
Dena Dorniani,1 Mohd Zobir bin Hussein,1 Aminu Umar Kura,2 Sharida Fakurazi,2 Abdul Halim Shaari,3 Zalinah Ahmad4 1Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology, 2Vaccines and Immunotherapeutics Laboratory ...
Dorniani D, Hussein MZ, Kura AU, Fakurazi S, Shaari AH, Ahmad Z   +5 more
doaj   +3 more sources

Effects of 6-mercaptopurine in pressure overload induced right heart failure.

PLoS ONE, 2019
BackgroundSeveral antineoplastic drugs have been proposed as new compounds for pulmonary arterial hypertension treatment but many have cardiotoxic side effects.
Julie Birkmose Axelsen, Stine Andersen, Xiao-Qing Sun, Steffen Ringgaard, Janus Adler Hyldebrandt, Kondababu Kurakula, Marie-José Goumans, Frances S de Man, Jens Erik Nielsen-Kudsk, Harm-Jan Bogaard, Asger Andersen   +10 more
doaj   +2 more sources

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation. [PDF]

J Sci Food Agric
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Bencsik T, Balázs O, Vida RG, Zsidó BZ, Hetényi C, Valentová K, Poór M.   +6 more
europepmc   +2 more sources

Genetic risk variants in intestinal inflammatory disorders [PDF]

, 2010
PhDThis thesis includes work on the genetics of intestinal inflammatory disorders, concentrating on coeliac disease and Crohn’s disease. It explores how common genetic variants influence risk of complex phenotypes including immunological intolerance to
Dubois, Patrick Charles Alexander
core   +4 more sources

Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease [PDF]

, 2008
AIM:To investigate the efficacy of 6-mercaptopurine (6-MP) in cases of azathioprine (AZA) hypersensitivity in patients with inflammatory bowel disease. METHODS: Twenty nine previously confirmed Crohn’s disease (CD) (n = 14) and ulcerative colitis (UC)
Nagy, Ferenc, Lonovics, János, Farkas, Kaludia, Molnár, Tamás, Szepes, Zoltán, Nyári, Tibor András   +5 more
core   +1 more source

6-thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party [PDF]

, 2006
Recently, the suggestion to use 6-thioguanine (6-TG) as an alternative thiopurine in patients with inflammatory bowel disease (IBD) has been discarded due to reports about possible (hepato) toxicity. During meetings arranged in Vienna and Prague in 2004,
Seiderer, J., Merwe, S. W. van der, Ochsenkühn, Thomas, Almer, S., Petritsch, W, Mulder, C. J. J, Seiderer, J, Vogelsang, H., Mulder, CJJ, Teml, A, Van Bodegraven, A. A., Teml, A., Herrlinger, K. R., Schwab, M., de Boer, NKH, Knoflach, P, van der Merwe, SW, Schwab, M, Reinisch, W., Ochsenkuhn, T, Reinisch, W, Knoflach, P., Petritsch, W., De Boer, N. K.H., De Boer, N. K. H, Van Der Merwe, S. W., Almer, Sven,, Vogelsang, H, Lukas, M., Ochsenkühn, T., van Bodegraven, AA, Lukas, M, Herrlinger, KR, Mulder, C. J.J., Bodegraven, A. A. van   +34 more
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Experts opinion on the practical use of azathioprine and 6-mercaptopurine in inflammatory bowel disease [PDF]

, 2016
The relevance of azathioprine and 6-mercaptopurine therapy in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, has been challenged in recent publications.
Kessler-Brondolo, Vera, Seibold, F., Rogler, Gerhard, Juillerat, P., Mottet, Christian, Froehlich, Florian, Rogler, G., Seibold, Frank, Schoepfer, A.M., Froehlich, F., Michetti, P., Cosnes, Jacques, Vavricka, S.R., Juillerat, Pascal, Michetti, Pierre, Cosnes, J., Vavricka, Stephan R, Schoepfer, Alain M, Mottet, C., Kessler-Brondolo, V.   +19 more
core   +2 more sources

6-Mercaptopurine, Monocytes, and Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2010
Atherosclerosis, the underlying cause of heart attack and stroke, appears to be an inflammatory disease driven by retention of modified lipoproteins in the artery wall.1 Markers of inflammation, such as high sensitivity C-reactive protein, are independent predictors of cardiovascular (CV) events.2 If atherosclerosis truly is an inflammatory disease ...
Macrae F, Linton, Sergio, Fazio
openaire   +2 more sources

Detection of Hypoxanthine from Inosine and Unusual Hydrolysis of Immunosuppressive Drug Azathioprine through the Formation of a Diruthenium(III) System

Biosensors, 2021
Hypoxanthine (hpx) is an important molecule for both biochemistry research and biomedical applications. It is involved in several biological processes associated to energy and purine metabolism and has been proposed as a biomarker for a variety of ...
Marta Orts-Arroyo, Isabel Castro, José Martínez-Lillo   +2 more
doaj   +1 more source