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Occurrence of Substituted p-Phenylenediamine Antioxidants and Their Quinone Derivatives in the Pearl River Estuary Water System, China [PDF]
ToxicsSubstituted p-phenylenediamines (PPDs) and their quinone derivatives (PPD-Qs) are emerging contaminants associated with tire-related antioxidants and antiozonants and have raised increasing concern because of their potential environmental effects ...
Yihao Yin +8 more
doaj +2 more sources
Ecotoxicology and Environmental SafetyBackground: N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q), a transformation product of tire rubber antioxidants, has been increasingly recognized as an emerging environmental contaminant with potential reproductive toxicity ...
Xiya Jiang +10 more
doaj +2 more sources
6PPD and 6PPD-Q Induce Mitochondrial Dysfunction in <i>Saccharomyces cerevisiae</i>. [PDF]
Int J Mol SciN-(1,3-dimethylbutyl)-N′phenyl-p-phenylenediamine, more commonly known as 6PPD, is a tire antiozonant used to prevent rubber oxidation and degradation. When 6PPD reacts with ozone, it becomes 6PPD-Quinone (6PPD-Q).
Braun E, Metcalf M, Kim K.
europepmc +2 more sources
Oxidative stress generated DNA damage by 6PPD and other tyre additives in A549 human lung epithelial cells [PDF]
Scientific ReportsTyre additives such as p-phenylenediamines (PPDs) and benzothiazoles (BTs) are ubiquitous in the environment. They have been frequently detected in urban air and have been detected in the human body.
Samuel Hyman +10 more
doaj +2 more sources
6PPD and 6PPD-Quinone in the Urban Environment: Assessing Exposure Pathways and Human Health Risks
Urban ScienceIn recent years, tires have become a prominent concern for researchers and environmentalists in regard to their potential threat of tire-derived pollutants (TDPs) to human health. Among these pollutants, N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine
Stanley Chukwuemeka Ihenetu +5 more
doaj +2 more sources
Ecotoxicology and Environmental Safety6PPD-quinone (6PPD-Q), a transformation product of the tire antioxidant 6PPD, is an emerging traffic-related contaminant with well-documented ecotoxicity in aquatic species.
Aimei Lu +11 more
doaj +2 more sources
Unveiling the Molecular Mechanism of 6PPD and 6PPD-Q in Lipid-Metabolism-Related Diseases Through Network Toxicology and Experimental Validation. [PDF]
Int J Mol Sci6PPD and its ozonation product 6PPD-quinone (6PPD-Q) are ubiquitous tire-derived pollutants linked to environmental and potential human health risks.
Li Z, Luo Y, Zhao J, Wang S, Zhang Y.
europepmc +2 more sources
ChemosphereThe environmental ubiquity of tire and road wear particles (TRWP) underscores the need to understand the occurrence, persistence, and environmental effects of tire-related chemicals in aquatic ecosystems. One such chemical is 6PPD-quinone (6PPD-Q), a transformation product of the tire antioxidant 6PPD. In urban stormwater runoff 6PPD-Q can exceed acute
Justin B Greer +2 more
exaly +3 more sources
Environment International, 2022 As a ubiquitous tire antidegradant, N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) is persistently released into the environment. It is highly toxic to aquatic organisms, and its transformation product 6PPD-quinone (6PPD-Q), is “very highly ...
Shanshan Di +8 more
doaj +1 more source
Advanced Quantification of Tire Wear Additives: 6PPD-Q as an Example [PDF]
Tire wear particles (TWP), produced from mechanical release, are a large anthropogenic pollutant source. N,N’-substituted p-phenylenediamine (PPD) is a group of compounds used as an additive in commercial rubber. They increase durability and protect the tires against high temperature, pressure, oxygen and ozone. Along the discovery of the PPDs toxicity
Krog, Maren
openaire +2 more sources