Results 71 to 80 of about 1,351,533 (180)

Enantioselectivity in blood-cerebrospinal fluid barrier permeability of substituted p-phenylenediamine quinones in patients with leptomeningeal metastasis

Ecotoxicology and Environmental Safety
Substituted p-phenylenediamine quinones (PPD-Qs), widespread environmental contaminants arising from rubber antioxidants, exhibit documented toxicity and have been detected in human biological matrices.
Yuxiang Weng, Zebin Fang, Xiaoyi Wang, Sihan Mao, Feng Xiao, Luyuan Zhang, Weijian Fan, Chao Zhang, Ping Lan, Renya Zhan, Kaiyuan Huang, Qingsheng Xu   +11 more
doaj   +1 more source

6PPD-quinone aggravates airway inflammation in neutrophilic asthma: Evidence from network toxicology and in vivo validation

Ecotoxicology and Environmental Safety
N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-Q), an emerging tire-derived environmental contaminant, is widely detected in airborne particles, raising concerns about its respiratory health effects.
Nishan Deng, Miaojuan Zhu, Lijie Yang, Hanxiang Nie   +3 more
doaj   +1 more source

6PPD-quinone affects the photosynthetic carbon fixation in cyanobacteria by extracting photosynthetic electrons

The Innovation
Photosynthetic carbon fixation by cyanobacteria plays a pivotal role in the global carbon cycle but is threatened by environmental pollutants. To date, the impact of quinones, with electron shuttling properties, on cyanobacterial photosynthesis is ...
Xiuqi You, Ximin Chen, Yi Jiang, Huan Chen, Juan Liu, Zhen Wu, Weiling Sun, Jinren Ni   +7 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Off the Beaten Path: Are Unpaved Roads and Recycled Tire Materials Pathways for 6PPD-Q to Enter the Environment? [PDF]

Efforts to expand the operational lifespan of rubber tires have led to the addition of sacrificial antiozonants, including 6PPD, into the rubber material to reduce ozone-induced oxidative damage. Recent studies have demonstrated the acutely toxic effects
Bryshun, Leland T
core  

Mitochondrial DNA copy number mediates PPD-Qs-induced lipid level alterations in humans

Ecotoxicology and Environmental Safety
In recent years, human exposure to p-phenylenediamine-derived quinone (PPD-Qs) has attracted great attention due to their potential toxic effects on humans.
Zhenling Fu, Weili Mao, Jianli Qu, Xilin Wu   +3 more
doaj   +1 more source

Distribution and Environmental Risk Assessment of 6PPD/Q Across Global Water Bodies: Data Mining

The rubber antioxidant 6PPD and its toxic quinone transformation product 6PPD-Q are emerging aquatic contaminants with fragmented global occurrence data.
Menghui Li, Pengrong Huang, Xinyan Shao, Yaolin Zhang   +3 more
core   +1 more source

Characterisation of tire wear particles and their chemical markers: A case study along a German highway

Case Studies in Chemical and Environmental Engineering
This case study investigates tire wear particles (TWP) and their chemical markers (6PPD-Q, DPG, 2-OHBT) in road dust and roadside soils along a German highway.
Faith Chebet Tumwet, Karin Fester, Stanislava Vrchovecká, Traugott Scheytt   +3 more
doaj   +1 more source

P-phenylenediamines and their quinones in estuarine-coastal sediments of Zhejiang Province: Occurrence, prioritization, and risk assessment

Emerging Contaminants
As emerging contaminants of concern, p-phenylenediamines (PPDs) and their quinone transformation products (PPD-Qs) serve as critical indicators of pollutant inputs from urban runoff and tire wear to coastal ecosystems.
Zhou Wu, Zhongyong Yan, Yanpeng Liang, Qinglin Mu, Zhaochao Deng, Lijia Jiang, Mingzhi Liu, Guanghao Sun, Zenghui Xu, Zhendong Li, Chunfang Zhang, Yanhong Li, Hanghai Zhou   +12 more
doaj   +1 more source

First Report on the Occurrence of N‑(1,3-Dimethylbutyl)‑N′‑phenyl‑p‑phenylenediamine (6PPD) and 6PPD-Quinone as Pervasive Pollutants in Human Urine from South China

N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its quinone derivative, 6PPD-quinone (6PPD-Q), have been found to be prevalent in the environment, but there are currently no data on their presence in humans.
Bowen Liang (5339090), Liang-Ying Liu (1762489), Mingjie Shen (9379710), Lixi Zeng (1517923), Yi Li (1144), Bibai Du (2562277)   +5 more
core   +1 more source