Results 11 to 20 of about 216 (131)

Time Course of Effects and Tissue Concentrations of 6PPDQ in Three Sensitive Salmonids with Additional Data for Two Centrarchid Species. [PDF]

Environ Sci Technol
Studies of 6PPD-quinone (6PPDQ) toxicity have identified both sensitive and resistant salmonid species at environmentally relevant concentrations. However, comparisons between species are complicated by varying testing conditions, which can limit the application to derivation of environmental quality guidelines.
Soucek DJ, Dorman RA, Candrl JS, Moody AH, Lane RF, Greer JB, Hansen JD, Steevens JA.   +7 more
europepmc   +5 more sources

Presence of N, N′-Substituted p-Phenylenediamine-Derived Quinones in Human Urine [PDF]

Toxics
Human exposure to various N,N′-substituted p-phenylenediamine-derived quinones (PPDQs) has been of increasing concern. Recent studies have examined N-phenyl-N′-(1,3-dimethylbutyl)-p-phenylenediamine-derived quinone (6PPDQ) in human urine to evaluate ...
Juxiu Huang, Hangbiao Jin, Yingying Zhu, Ruyue Guo, Lisha Zhou, Xiaoyu Wu   +5 more
doaj   +3 more sources

Alterations of gut microbiota and its metabolomics in children with 6PPDQ, PBDE, PCB, and metal(loid) exposure [PDF]

Journal of Hazardous Materials
The composition and metabolites of the gut microbiota can be altered by environmental pollutants. However, the effect of co-exposure to multiple pollutants on the human gut microbiota has not been sufficiently studied. In this study, gut microorganisms and their metabolites were compared between 33 children from Guiyu, an e-waste dismantling and ...
Ilja Nolte, Xiang Zeng, Xia Huo
exaly   +4 more sources

Child exposure to N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its derived quinone (6PPDQ) in e-waste areas: Urinary concentrations, sources, and health effect assessment [PDF]

Journal of Environmental Sciences
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPDQ) and its parent 6PPD are ubiquitous in the environment and may induce multi-endpoint toxicity. Electronic waste (e-waste) dismantling is an under-recognized source of 6PPD and 6PPDQ emissions, and there is a lack of epidemiological investigations into their presence and health effects in
Zongwei Cai, Hongli Tan
exaly   +4 more sources

Combined Toxicity Effects and Health Risks of Microplastics and Multiple Pollutants. [PDF]

J Toxicol
Microplastics, as emerging pollutants, are ubiquitously present globally and pose significant threats to both ecosystems and human health. These pollutants not only exert direct toxicity on the environment and living organisms but also influence the toxicity of other pollutants through mechanisms such as adsorption and carrier effects. The health risks
Wu L, Zhou Y, Xing M, Niu H, Li X, Chen Z, Lou X.   +6 more
europepmc   +2 more sources

Targeting the PI3K-AKT pathway to alleviate 6PPDQ-induced cognitive impairment associated with metabolic syndrome

Ecotoxicology and Environmental Safety
6PPD-quinone (6PPDQ), a derivative of the antioxidant 6PPD used in the rubber industry, has been implicated in environmental and public health risks. To explore its impact on metabolic and cognitive functions, we orally administered 6PPDQ to mice and ...
Leisheng Wang, Yifei Fu, Shiwei Xu, Enhong Chen, Shuo Zhang, Dongjie Yang, Youzhao He, Yuanlong Gu, Yong Mao, Fenglai Yuan, Hao Hu   +10 more
doaj   +3 more sources

6PPDQ promotes the malignant progression of colorectal cancer via enhancing EGF/EGFR signaling

Ecotoxicology and Environmental Safety
6PPD-quinone (6PPDQ), a transformation product of the rubber antioxidant 6PPD, is a newly identified pollutant found globally. Originating mainly from tire wear particles, it contaminates water bodies, the atmosphere, and the food chain, leading to ...
Zhang Yuan Fang, Hong Dan, Liu Sha, Liu Ya Wei, Song Lei, Wang Zhi Yu, Suo Si Yuan, Qin Yan, Zhang Lan, Tan Peng   +9 more
doaj   +2 more sources

Oxidative stress generated DNA damage by 6PPD and other tyre additives in A549 human lung epithelial cells [PDF]

Scientific Reports
Tyre additives such as p-phenylenediamines (PPDs) and benzothiazoles (BTs) are ubiquitous in the environment. They have been frequently detected in urban air and have been detected in the human body.
Samuel Hyman, Rea Bilić, Annie Jensen, Siriel Saladin, Yurii Tsybrii, Oleksii Nosko, David Topping, Adam Boies, Chiara Giorio, Martin Roursgaard, Peter Møller   +10 more
doaj   +2 more sources

What research exists on the presence of 6PPD-Q in different environmental media? A systematic map protocol [PDF]

Environmental Evidence
Background Automobiles are ubiquitous in the modern world, and chemicals leaching from car tires and from the tire wear particles produced during driving can be toxic to the environment, particularly in aquatic ecosystems.
Sultan Aljohani, Mary Engels, Kenneth E. Wallen   +2 more
doaj   +2 more sources

Urinary exposure level of emerging chemicals in Chinese pregnant women and their associations with oxidative stress

Emerging Contaminants
Emerging chemicals (ECs), including parabens, bisphenols, bisphenol diglycidyl ethers, N,N′-substituted p-phenylenediamines, and benzotriazoles/benzothiazoles (BTH/BTRs), are widely used in industrial and consumer products.
Henglin Zhang, Yuxian Liu, Yanan Zhao, Jiye Zhang, Luhan Yang, Guanglan Zhang, Yanpeng Cai, Lan Yang, Jianya Xi, Ziliang Wang, Hong Liang, Maohua Miao, Tao Zhang, Jingchuan Xue   +13 more
doaj   +2 more sources