Results 131 to 140 of about 37,102 (171)

Lipid-Laden Macrophages in Pulmonary Diseases. [PDF]

Cells
Zhu Y, Choi D, Somanath PR, Zhang D.
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Comparative analysis of reproductive hormones, serum biochemical indexes and ovarian metabolites in Muscovy breeder duck at different laying stages. [PDF]

Poult Sci
Yang W, Lang X, Song D, Xu H, Zhang C, Guo L, Chen X.   +6 more
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Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages. [PDF]

Microbiol Mol Biol Rev
de Crécy-Lagard V, Hutinet G, Cediel-Becerra JDD, Yuan Y, Zallot R, Chevrette MG, Ratnayake RMMN, Jaroch M, Quaiyum S, Bruner S.   +9 more
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Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms. [PDF]

Biochem Soc Trans
Tai MDS, Gamiz-Arco G, Martinez A.
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CD36 down regulation by the macrophage antioxidant 7,8-dihydroneopterin through modulation of PPAR-γ activity

Free Radical Research, 2022
CD36 is the key scavenger receptor driving the formation of cholesterol-loaded foam cells, the principal cellular component of atherosclerotic plaques. CD36 is down regulated by 7,8-dihydroneopterin, a potent superoxide and hypochlorite scavenging antioxidant generated by interferon-γ stimulated macrophages. 7,8-dihydroneopterin downregulates CD36 mRNA
Nooshin, Ghodsian, Anthony, Yeandle, Barry D, Hock, Steven P, Gieseg   +3 more
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Nucleoside transporters are critical to the uptake and antioxidant activity of 7,8-dihydroneopterin in monocytic cells

Free Radical Research, 2020
7,8-Dihydroneopterin protects cells intracellularly from oxidative stress-induced death, but its mode of transport across the cell membrane is unknown. Nucleosides, such as guanosine, are transported via nucleoside transporters of the equilibrative and concentrative forms.
Tejraj V. Janmale, Angus Lindsay, Steven P. Gieseg   +2 more
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Oxidation of 7,8-Dihydroneopterin by Hypochlorous Acid Yields Neopterin

Biochemical and Biophysical Research Communications, 2000
In vitro, interferon-gamma stimulates primate monocytes/macrophages to produce the pteridines neopterin and 7,8-dihydroneopterin. These pteridines are capable of modulating the oxidative potential of reactive species. Neopterin is pro-oxidative whereas 7, 8-dihydroneopterin is an effective antioxidant. In the presence of oxygen, 7,8-dihydroneopterin is
Bernhard Widner, Dietmar Fuchs, Christiane Mayr, Barbara Wirleitner   +3 more
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Formation of Oxygen Radicals in Solutions of 7,8-Dihydroneopterin

Biochemical and Biophysical Research Communications, 1999
Neopterin and 7,8-dihydroneopterin, two compounds which are secreted by activated macrophages, have been shown to interfere with radicals generated by cellular and certain chemical systems. Reduced pterins were reported to scavenge whereas aromatic pterins promoted or reduced radical mediated reactions or had no effect.
Barbara Wirleitner, Dietmar Fuchs, Tanja B. Grammer, Gabriele Baier-Bitterlich, Karl Oettl, Gilbert Reibnegger   +5 more
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Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterin

Free Radical Research, 2001
Neopterin and the reduced form, 7,8-dihydroneopterin (78NP) are pteridines released from macrophages when stimulated with gamma-interferon in vivo. The role of 78NP in inflammatory response is unknown though neopterin has been used clinically as a marker of immune cell activation, due to its very fluorescent nature.
Ghassan J. Maghzal, Steven P. Gieseg, Dylan M. Glubb   +2 more
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Neopterin formation through radical scavenging of superoxide by the macrophage synthesised antioxidant 7,8-dihydroneopterin

Free Radical Biology and Medicine, 2020
Clinical measurement of neopterin has been extensively used as a marker of inflammation but the in vivo mechanism generating neopterin is poorly understood. Neopterin is described as the oxidation product of 7,8-dihydroneopterin, a potent antioxidant generated by monocyte/macrophages in response to interferon-γ.
Barry D. Hock, Andrew Cousins, Nina Steyn, Steven P. Gieseg, Steven P. Gieseg, Steven P. Gieseg, Hannah M. Prebble, Anastasia A. Shchepetkina, Sean Cross, Gregory Baxter-Parker   +9 more
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