Results 41 to 50 of about 320 (132)

Smith-Lemli-Opitz Syndrome

open access: yesPediatric Neurology Briefs, 1998
Two sibs, a male aged 3 years and female aged 7 months, with a variant of Smith-Lemli-Opitz (SLO) syndrome and atypical sterol metabolism are reported from the Kennedy Krieger Institute, Johns Hopkins University, Baltimore, MD.
J Gordon Millichap
doaj   +1 more source

Does the Combination of Abdominal Obesity and Vitamin D Deficiency Increase the Risk of Death in Individuals Aged 50 or Older? Evidence From the ELSA Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6607-6617, August 2026.
ABSTRACT Aims Despite the known association between abdominal obesity (AO) and vitamin D deficiency, it remains unclear whether this combination is associated with higher mortality risk. We investigated whether the coexistence of AO and vitamin D deficiency elevates the risk of death.
Joyce da Silva Milliati   +7 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

The Photochemical Dehydrogenation of Ergosterol and 7-Dehydrocholesterol [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1939
Abstract Ergopinacone and 7-dehydrocholesterol-pinacone have been prepared by two different methods, viz., the boiling method and the carbon dioxide method. The products obtained by the two methods as well as diacetates and dibenzoates derived from them have been compared.
openaire   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 8, Page 2511-2547, August 2026.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon   +2 more
wiley   +1 more source

Alliin Regulates Intracellular Cholesterol Metabolism Through the PCSK9/LDLR Axis in Ox‐LDL‐Induced HepG2 Cells: A Proteomics Study

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This study demonstrates that alliin reduces intracellular lipid accumulation and alters protein expression in ox‐LDL‐induced HepG2 cells. These effects are linked to cholesterol metabolism and the PPAR and PI3K/Akt signaling pathways. Mechanistically, alliin regulates the PCSK9/LDLR axis, indicating its role in maintaining intracellular cholesterol ...
Yuanyuan Tang, Xiaoshi Liu
wiley   +1 more source

Human Milk Bioactive Compounds and Psychomotor Outcomes in Infants and Children: A Systematic Review

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 14, 29 July 2026.
In our review, we assess the role of HM fatty acids, oligosaccharides, proteins, and carotenoids, on psychomotor development in children up to 18 years. Findings suggest that HM BCs, particularly n‐3 PUFAs and fucosylated HMOs, might contribute to a favorable psychomotor development in infancy, preschool age, and school age.
Lara Huber   +3 more
wiley   +1 more source

Occurrence of isomeric dehydrocholesterols in human plasma.

open access: yesJournal of Lipid Research, 1991
Three isomeric dehydrocholesterols were found in plasma from healthy subjects and patients with abnormal production or metabolism of cholesterol.
M Axelson
doaj   +1 more source

Alleviating Redox Imbalance Enhances 7-Dehydrocholesterol Production in Engineered Saccharomyces cerevisiae. [PDF]

open access: yesPLoS ONE, 2015
Maintaining redox balance is critical for the production of heterologous secondary metabolites, whereas on various occasions the native cofactor balance does not match the needs in engineered microorganisms.
Wan Su   +5 more
doaj   +1 more source

Ontogenetic Sequence of Differential Gene Expression in Predator‐Induced Daphnia pulex

open access: yesMolecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT In response to predators, many Daphnia species develop inducible morphological defenses. These traits are phenotypically plastic, meaning their production is suppressed in the absence of the predator. While previous studies have identified several neurohumoral factors and candidate genes involved in the development of the defenses, the ...
Andrey Rozenberg   +5 more
wiley   +1 more source

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