Results 31 to 40 of about 76,183,421 (152)

Avoiding False Identification of 7-Hydroxymitragynine in Kratom Products Using a Multicriteria LC-MS Confirmation. [PDF]

J Am Soc Mass Spectrom
Sheehan D, Li Y, Meckler E, Upton R, Zhang M.   +4 more
europepmc   +2 more sources

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Life, 2022
Mitragyna is a genus belonging to the Rubiaceae family and is a plant endemic to Asia and Africa. Traditionally, the plants of this genus were used by local people to treat some diseases from generation to generation.
Islamudin Ahmad, Wisnu Cahyo Prabowo, Muhammad Arifuddin, Jaka Fadraersada, Niken Indriyanti, Herman Herman, Reza Yuridian Purwoko, Firzan Nainu, Anton Rahmadi, Swandari Paramita, Hadi Kuncoro, Nur Mita, Angga Cipta Narsa, Fajar Prasetya, Arsyik Ibrahim, Laode Rijai, Gemini Alam, Abdul Mun’im, Sukanya Dej-adisai   +18 more
doaj   +1 more source

An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021

Clinical and Translational Science, Volume 16, Issue 6, Page 1002-1011, June 2023., 2023
Abstract Kratom is a widely used Asian botanical that has gained popularity in the United States due to a perception that it can treat pain, anxiety, and opioid withdrawal symptoms. The American Kratom Association estimates 10–16 million people use kratom.
Xiaotong Li, Patrick Ndungu, Sanya B. Taneja, Maryann R. Chapin, Susan B. Egbert, Krishi Akenapalli, Mary F. Paine, Sandra L. Kane‐Gill, Richard D. Boyce   +8 more
wiley   +1 more source

Drug testing for mitragynine and kratom: Analytical challenges and medico‐legal considerations

Drug Testing and Analysis, Volume 15, Issue 2, Page 213-219, February 2023., 2023
The use of kratom, that is, leaves from the Southeast Asian tree Mitragyna speciosa, has spread to the Western world. Kratom contain several alkaloids including mitragynine and its three diastereomers mitraciliatine, speciogynine and speciociliatine. In Sweden, only mitragynine is classified.
Anders Helander, Alexia Rylski
wiley   +1 more source

A systematic review of (pre)clinical studies on the therapeutic potential and safety profile of kratom in humans

Human Psychopharmacology: Clinical and Experimental, Volume 37, Issue 1, January 2022., 2022
Abstract Introduction Kratom (Mitragyna speciosa) is a tropical plant traditionally used as an ethnomedicinal remedy for several conditions in South East Asia. Despite the increased interest in its therapeutical benefits in Western countries, little scientific evidence is available to support such claims, and existing data remain limited to kratom's ...
Elisabeth Prevete, Kim Paula Colette Kuypers, Eef Lien Theunissen, Ornella Corazza, Giuseppe Bersani, Johannes Gerardus Ramaekers   +5 more
wiley   +1 more source

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder

Frontiers in Pharmacology, 2021
Background and Purpose:Mitragyna speciosa extract and kratom alkaloids decrease alcohol consumption in mice at least in part through actions at the δ-opioid receptor (δOR).
Anna M. Gutridge, Soumen Chakraborty, Balazs R. Varga, Elizabeth S. Rhoda, Alexander R. French, Alexander R. French, Arryn T. Blaine, Quinten H. Royer, Haoyue Cui, Jinling Yuan, Robert J. Cassell, Robert J. Cassell, Márk Szabó, Susruta Majumdar, Richard M. van Rijn, Richard M. van Rijn, Richard M. van Rijn   +16 more
doaj   +1 more source

Kratom Consumption can be Addictive and have Adverse Health Effects [PDF]

Novelty in Clinical Medicine, 2022
Kratom, also known as herbal speed, is the powdered leaves of the Asian kratom tree (Mitragyna speciosa Korth.). The consumption of kratom powder or kratom tea for diarrhea, inflammation, fever, and pain, but also for anxiety and depression is based on ...
Martin Hofmeister
doaj   +1 more source

Chromatograms of mitragynine (MG) and 7-hydroxymitragynine (7-OHMG) authentic standards identified using LC-MS.

, 2023
Chromatograms of mitragynine (MG) and 7-hydroxymitragynine (7-OHMG) authentic standards identified using LC-MS.
Rubashiny Veeramohan (14822709), Sharif Mahsufi Mansor (8071907), Kamalrul Azlan Azizan (6183800), Mohd Fauzi Abd Razak (14822712), Wan Mohd Aizat (6524270), Syarul Nataqain Baharum (6524273), Arief Izzairy Zamani (9358474), Nur Sabrina Mohd Yusof (14822715), Hoe-Han Goh (3559331), Chyan Leong Ng (3079596)   +9 more
core   +1 more source

Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance.

PLoS ONE, 2022
Leaves harvested from kratom [Mitragyna speciosa (Korth.)] have a history of use as a traditional ethnobotanical medicine to combat fatigue and improve work productivity in Southeast Asia. In recent years, increased interest in the application and use of
Mengzi Zhang, Abhisheak Sharma, Francisco León, Bonnie Avery, Roger Kjelgren, Christopher R McCurdy, Brian J Pearson   +6 more
doaj   +2 more sources

A Critical Review of the Neuropharmacological Effects of Kratom: An Insight from the Functional Array of Identified Natural Compounds

Molecules, 2023
Kratom (Mitragyna speciosa Korth. Havil) has been considered a narcotic drug for years, barred by the law in many parts of the world, while extensive research over the past few decades proves its several beneficial effects, some of which are still in ...
Rahni Hossain, Abida Sultana, Manit Nuinoon, Kunwadee Noonong, Jitbanjong Tangpong, Kazi Helal Hossain, Md Atiar Rahman   +6 more
doaj   +1 more source