Results 51 to 60 of about 824 (158)
Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective
Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities.
Faisal Omar +6 more
doaj +1 more source
A Case Report of Kratom-Induced Psychiatric Decompensation
Introduction Kratom (Mitragyna speciosa) is an herb found in South East Asia belonging to the Rubiacea family, the active constituents being Mitragynine and 7-hydroxymitragynine. Sold as a dietary supplement in the form of a leaf, tablet, and powder, it
E. Garrels +3 more
doaj +1 more source
Novel psychoactive substances of interest for psychiatry [PDF]
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John +3 more
core +1 more source
Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow +8 more
core +1 more source
Kratom Abuse Potential 2021: An Updated Eight Factor Analysis
Drugs are regulated in the United States (US) by the Controlled Substances Act (CSA) if assessment of their abuse potential, including public health risks, show such control is warranted.
Jack E. Henningfield +2 more
doaj +1 more source
This study aimed to determine the effects of different concentrations and combinations of the phytohormones 2,4‐dichlorophenoxy acetic acid (2,4‐D), kinetin, 6‐benzylaminopurine (BAP), and 1‐naphthaleneacetic acid (NAA) on callus induction and to demonstrate the role of elicitors and exogenous precursors on the production of mitragynine in a Mitragyna ...
Nor Nahazima Mohamad Zuldin +10 more
wiley +1 more source
An Alternative Paradigm for the Role of Antimalarial Plants in Africa
Most investigations into the antimalarial activity of African plants are centered on finding an indigenous equivalent to artemisinin, the compound from which current frontline antimalarial drugs are synthesized. As a consequence, the standard practice in ethnopharmacological research is to use in vitro assays to identify compounds that inhibit ...
Steven Maranz, Yasushi Shigeri
wiley +1 more source
Kratom use disorder as a gateway to an opioid use disorder
Introduction Kratom (Mitragyna speciosa) is a psychoactive substance native to Thailand and Southeast Asia with stimulant-like effects at lower doses and opioid-like effects at higher doses.
A. C. Borges, D. Machado
doaj +1 more source
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS
Mitragyna speciosa is a psychoactive plant known as “ketum” in Malaysia and “kratom” in Thailand. This plant is distinctly known to produce two important alkaloids, namely mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG) that can bind to opioid ...
Rubashiny Veeramohan +7 more
doaj +1 more source
Identification of “Kratom” (Mitragyna speciosa) Alkaloids in Commercially Available Products [PDF]
“Kratom” is the common name for the botanical mitragyna speciosa. It is a tree native to Southeast Asia in which leaves contain the psychoactive alkaloids mitragynine and 7-hydroxymitragynine. Kratom is often ingested as teas, chewed, or smoked.
Grzymkowski, Julia +2 more
core +1 more source

